Before taking Azasite Ophthalmic (azithromycin) 1%, tell your doctor or pharmacist if you are allergic to it; or to other antibiotics (such as erythromycin, clarithromycin, telithromycin); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using Azasite Ophthalmic (azithromycin) 1%, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease, a certain muscle disease (myasthenia gravis).
Azithromycin may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can infrequently result in serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away.
The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation. Before using Azasite Ophthalmic (azithromycin) 1%, tell your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain heart problems (heart failure, slow heartbeat, QT prolongation in the EKG), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death).
Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your doctor about using Azasite Ophthalmic (azithromycin) 1% safely.
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
Older adults may be more sensitive to the side effects of Azasite Ophthalmic (azithromycin) 1%, especially QT prolongation (see above).
During pregnancy, Azasite Ophthalmic (azithromycin) 1% should be used only when clearly needed. Discuss the risks and benefits with your doctor.
Azasite Ophthalmic (azithromycin) 1% passes into breast milk. Consult your doctor before breast-feeding.
Store in the refrigerator or at room temperature. Do not store in the bathroom. Discard after 10 days. Keep all medications away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
Azithromycin is used to treat a wide variety of bacterial infections. It is a macrolide-type antibiotic. It works by stopping the growth of bacteria.
Azasite Ophthalmic (azithromycin) 1% will not work for viral infections (such as common cold, flu). Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness.
Read the Patient Information Leaflet if available from your pharmacist before you start taking Azasite Ophthalmic (azithromycin) 1% and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
Take Azasite Ophthalmic (azithromycin) 1% by mouth as directed by your doctor, usually once daily with or without food. You may take Azasite Ophthalmic (azithromycin) 1% with food if stomach upset occurs. The dosage is based on your medical condition and response to treatment. For children, the dose is also based on weight.
Shake the suspension well before using. Carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose. If your child vomits the 1-day treatment dose within 30 minutes, call your doctor to see if you need to repeat the dose.
Antibiotics work best when the amount of medicine in your body is kept at a constant level. Therefore, take Azasite Ophthalmic (azithromycin) 1% at the same time each day.
Continue to take Azasite Ophthalmic (azithromycin) 1% until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping the medication too early may allow bacteria to continue to grow, which may result in a return of the infection.
Antacids containing aluminum or magnesium may decrease the absorption of Azasite Ophthalmic (azithromycin) 1% if taken at the same time. If you take an antacid that contains aluminum or magnesium, wait at least 2 hours before or after taking Azasite Ophthalmic (azithromycin) 1%.
Tell your doctor if your condition persists or worsens.
Stomach upset, diarrhea/loose stools, nausea, vomiting, or abdominal pain may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
Remember that your doctor has prescribed Azasite Ophthalmic (azithromycin) 1% because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using Azasite Ophthalmic (azithromycin) 1% do not have serious side effects.
Tell your doctor right away if any of these unlikely but serious side effects occur: hearing changes (such as decreased hearing, deafness), eye problems (such as drooping eyelids, blurred vision), difficulty speaking/swallowing, muscle weakness, signs of liver problems (such as unusual tiredness, persistent nausea/vomiting, severe stomach/abdominal pain, yellowing eyes/skin, dark urine).
Get medical help right away if any of these rare but serious side effects occur: fast/irregular heartbeat, severe dizziness, fainting.
Azasite Ophthalmic (azithromycin) 1% may rarely cause a severe intestinal condition (Clostridium difficile-associated diarrhea) due to a resistant bacteria. This condition may occur during treatment or weeks to months after treatment has stopped. Do not use anti-diarrhea products or narcotic pain medications if you have any of the following symptoms because these products may make them worse. Tell your doctor immediately if you develop: persistent diarrhea, abdominal or stomach pain/cramping, blood/mucus in your stool.
Use of Azasite Ophthalmic (azithromycin) 1% for prolonged or repeated periods may result in oral thrush or a new yeast infection. Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge, or other new symptoms.
A very serious allergic reaction to Azasite Ophthalmic (azithromycin) 1% is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
An allergic reaction to Azasite Ophthalmic (azithromycin) 1% may return even if you stop the drug. If you have an allergic reaction, continue to watch for any of the above symptoms for several days after your last dose.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Click here to view a more detailed list of Azasite Ophthalmic side effects.
If you miss a dose of Azasite Ophthalmic (azithromycin) 1%, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
See also How to Use section.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
Some products that may interact with Azasite Ophthalmic (azithromycin) 1% include: live bacterial vaccines.
Although most antibiotics probably do not affect hormonal birth control such as pills, patch, or ring, some antibiotics may decrease their effectiveness. This could cause pregnancy. Examples include rifamycins such as rifampin or rifabutin. Be sure to ask your doctor or pharmacist if you should use additional reliable birth control methods while using this antibiotic.
Many drugs besides Azasite Ophthalmic (azithromycin) 1% may affect the heart rhythm (QT prolongation), including amiodarone, disopyramide, dofetilide, dronedarone, ibutilide, pimozide, procainamide, quinidine, sotalol, among others.