Before using Differin XP Gel (Adapalene) 0.3%, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using Differin XP Gel (Adapalene) 0.3%, tell your doctor or pharmacist your medical history, especially of: eczema.
Differin XP Gel (Adapalene) 0.3% may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Weather extremes such as wind or cold may also be irritating to the skin. Use a sunscreen daily and wear protective clothing when outdoors. Wait until your skin has completely recovered from a sunburn before using Differin XP Gel (Adapalene) 0.3%.
Avoid electrolysis, waxing and chemical depilatories for hair removal on the treated areas while using this product.
If you have recently used products containing sulfur, resorcinol or salicylic acid, use Differin XP Gel (Adapalene) 0.3% with caution. Wait until the effects of such products on the skin have decreased before using Differin XP Gel (Adapalene) 0.3%.
Differin XP Gel (Adapalene) 0.3% should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.
It is not known whether Differin XP Gel (Adapalene) 0.3% passes into breast milk. Consult your doctor before breast-feeding.
Store at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture. Different forms of Differin XP Gel (Adapalene) 0.3% may have different storage requirements. Read the package labeling or ask your pharmacist for the storage requirements for the product you are using. Gel preparations are flammable. Do not expose to heat or fire sources. Do not smoke during use. Keep all medicines away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.
Differin XP Gel (Adapalene) 0.3% is used to treat acne. It may decrease the number and severity of acne pimples and promote quick healing of pimples that do develop. Differin XP Gel (Adapalene) 0.3% belongs to a class of medications called retinoids. It works by affecting the growth of cells and decreasing swelling and inflammation.
Wash your hands before applying Differin XP Gel (Adapalene) 0.3%. Gently clean the affected skin with a mild or soapless cleanser and pat dry. Use your fingertips to apply a small amount of medication in a thin layer, usually once daily at bedtime, or as directed by your doctor. A gauze pad or cotton swab can be used to apply the solution.
Use Differin XP Gel (Adapalene) 0.3% on the skin only. Do not apply to the inner lip area or inside the nose/mouth. Do not apply to cut, scraped, sunburned, or eczema-affected skin.
Avoid getting Differin XP Gel (Adapalene) 0.3% in your eyes. If Differin XP Gel (Adapalene) 0.3% gets into your eyes, flush with large amounts of water. Call your doctor if eye irritation develops. Wash your hands after using the medication to avoid accidentally getting it in your eyes.
During the first few weeks of using Differin XP Gel (Adapalene) 0.3%, your acne might appear worse because the medication is working on pimples forming inside the skin. It may take up to 8-12 weeks to notice results from Differin XP Gel (Adapalene) 0.3%.
Use it regularly in order to get the most benefit from it. To help you remember, use it at the same time each day. Do not use a larger amount or use it more frequently than recommended. Your skin will not improve any faster, and it will increase the risk of developing redness, peeling and pain.
Differin XP Gel (Adapalene) 0.3% is available in different strengths and forms (e.g., gel, cream, solution). The best type of medication for you to use will depend on the condition of your skin and your response to therapy. Inform your doctor if your condition persists or worsens.
A brief sensation of warmth or stinging may occur immediately after applying the medication. Skin redness, dryness, itching, scaling, mild burning, or worsening of acne may occur during the first 2-4 weeks of using the medication. These effects usually decrease with continued use. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Your doctor may want you to decrease how often you use Differin XP Gel (Adapalene) 0.3%, change the strength, or have you stop using it.
Remember that your doctor has prescribed Differin XP Gel (Adapalene) 0.3% because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using Differin XP Gel (Adapalene) 0.3% do not have serious side effects.
Tell your doctor immediately if any of these unlikely but serious side effects occur: very red/irritated skin, an intense burning sensation, eye redness and watering (conjunctivitis), eyelid swelling, skin discoloration.
A very serious allergic reaction to Differin XP Gel (Adapalene) 0.3% is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Click here to view a more detailed list of Differin XP Gel side effects.
If you forget to use Differin XP Gel (Adapalene) 0.3%, use it as soon as you remember if you remember the same day. If you don't remember until morning, wait until your next dose is scheduled.
See also Precautions section.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
Some products that may interact with Differin XP Gel (Adapalene) 0.3% include: products containing alpha hydroxy acids, products containing glycolic acid, hair perming solutions, alcohol/lime/menthol-containing products (such as astringents, toners, shaving lotions), medicated or abrasive soaps and cleansers, products containing sulfur, resorcinol or salicylic acid, soaps and cosmetics with a strong drying effect, other drugs that may increase your sensitivity to sunlight (e.g., fluoroquinolones such as ciprofloxacin, tetracyclines, thiazide water pills such as hydrochlorothiazide, sulfa drugs such as sulfamethoxazole, phenothiazines such as chlorpromazine).