Before using Efudex Cream (fluorouracil) 5%, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Efudex Cream (fluorouracil) 5% should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: a certain enzyme deficiency (dihydropyrimidine dehydrogenase - DPD).
Before using Efudex Cream (fluorouracil) 5%, tell your doctor or pharmacist your medical history, especially of: red/irritated/infected/open sores on skin.
Efudex Cream (fluorouracil) 5% may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when outdoors. After using Efudex Cream (fluorouracil) 5% cream, wait 2 hours before applying sunscreen or moisturizer to the treated area. Do not use other skin products including creams, lotions, medications, or cosmetics unless instructed by your doctor to do so.
Efudex Cream (fluorouracil) 5% must not be used during pregnancy. It may harm an unborn baby. If you become pregnant or think you may be pregnant, inform your doctor immediately. Consult your doctor for more details and to discuss reliable forms of birth control.
It is not known if Efudex Cream (fluorouracil) 5% passes into breast milk. Due to the potential risk to a nursing infant, breast-feeding is not recommended while using Efudex Cream (fluorouracil) 5%. Consult your doctor before breast-feeding.
Store at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.
Efudex Cream (fluorouracil) 5% is used on the skin to treat pre-cancerous and cancerous skin growths. Efudex Cream (fluorouracil) 5% belongs to a class of medications known as anti-metabolites. It works by blocking the growth of abnormal cells that cause the skin condition.
Read the Patient Information Leaflet provided by your pharmacist before you start using Efudex Cream (fluorouracil) 5% and each time you get a refill. If you have any questions, consult your doctor or pharmacist.
Use Efudex Cream (fluorouracil) 5% as directed by your doctor. Before you apply Efudex Cream (fluorouracil) 5% to the skin, clean the affected area and dry well. Wait 10 minutes, then apply a small amount of medication to the affected skin, using just enough to cover the area with a thin film. Wash your hands immediately after applying Efudex Cream (fluorouracil) 5%, even if you have used gloves.
The treated area may become unsightly during treatment and in some cases for several weeks after treatment. Do not cover the area with tight dressings or plastic bandages. Check with your doctor whether you may cover the treated area loosely with gauze.
Avoid applying Efudex Cream (fluorouracil) 5% in or around the eyes or eyelids. Also, do not apply Efudex Cream (fluorouracil) 5% inside the nose or mouth. If you do get the medication in these areas, rinse with plenty of water.
Use Efudex Cream (fluorouracil) 5% exactly as prescribed. Do not stop using Efudex Cream (fluorouracil) 5% without consulting your doctor. Do not increase your dose or use it more often than directed. Your condition will not clear faster, but side effects will be increased.
If your condition worsens or does not improve, consult your doctor or pharmacist promptly.
Skin irritation, burning, redness, dryness, pain, swelling, tenderness, or changes in skin color may occur at the site of application. Eye irritation (e.g., stinging, watering), trouble sleeping, irritability, temporary hair loss, or abnormal taste in the mouth may also occur.
If any of these effects persist or worsen, contact your doctor or pharmacist promptly.
Remember that your doctor has prescribed Efudex Cream (fluorouracil) 5% because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using Efudex Cream (fluorouracil) 5% do not have serious side effects.
Tell your doctor immediately if any of these rare but very serious side effects occur: stomach/abdominal pain, bloody diarrhea, vomiting, signs of infection (e.g., fever, chills, persistent sore throat), easy bruising/bleeding, mouth sores.
A very serious allergic reaction to Efudex Cream (fluorouracil) 5% is rare. However, seek immediate medical attention if you notice any of the following symptoms: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Click here to view a more detailed list of Efudex Cream side effects.
If you miss a dose of Efudex Cream (fluorouracil) 5%, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.
Before using Efudex Cream (fluorouracil) 5%, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use.
Keep a list of all your medications with you, and share the list with your doctor and pharmacist.