Before taking Malarone (atovaquone/proguanil), tell your doctor or pharmacist if you are allergic to either atovaquone or proguanil; or if you have any other allergies.
Usually, Malarone (atovaquone/proguanil) should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: severely decreased kidney function (creatinine clearance less than 30 milliliters per minute).
However, your doctor may choose to use this for treatment of a malaria attack and monitor you closely, even if you have severely decreased kidney function.
Before using Malarone (atovaquone/proguanil), tell your doctor or pharmacist your medical history, especially of: current diarrhea, current vomiting, liver problems.
Malarone (atovaquone/proguanil) may make you dizzy. Use caution while driving, using machinery, or doing any activity that requires alertness. Limit alcoholic beverages.
During pregnancy, Malarone (atovaquone/proguanil) should be used only when clearly needed. While you are pregnant, travel to an area with malaria places you and your infant at a much higher risk for death and other problems. Discuss the risks and benefits of malaria prevention with your doctor.
The proguanil in Malarone (atovaquone/proguanil) passes into breast milk. Consult your doctor before breast-feeding.
IMPORTANT NOTE: The preceding information is intended to heighten awareness of health information and does not suggest diagnosis or treatment. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Store at room temperature at 77 degrees F (25 degrees C) away from light and moisture. Brief storage between 59-86 degrees F (15-30 degrees C) is permitted. Do not store in the bathroom. Keep all medicines away from children and pets.
Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.
IMPORTANT NOTE: The preceding information is intended to heighten awareness of health information and does not suggest diagnosis or treatment. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Take Malarone (atovaquone/proguanil) by mouth with food or a milky drink (e.g., milk, milkshake). For prevention of malaria, take Malarone (atovaquone/proguanil) usually once daily at the same time each day. Start Malarone (atovaquone/proguanil) 1-2 days before you enter the malaria area, and continue for 7 days after leaving.
For treatment of an attack of malaria, take Malarone (atovaquone/proguanil) usually once daily for 3 days. Usually, this dose will be larger than the dose used to prevent malaria.
If you have trouble swallowing tablets, Malarone (atovaquone/proguanil) may be crushed and mixed with condensed milk. Take the entire mixture immediately. Do not save for future use.
If you vomit within 1 hour of taking a dose, repeat the dose. If you have persistent vomiting after taking Malarone (atovaquone/proguanil), contact a doctor immediately for another medication.
Dosage of Malarone (atovaquone/proguanil) is based on your weight, medical condition, and response to treatment.
It is very important to continue taking Malarone (atovaquone/proguanil) exactly as prescribed by your doctor. Malarone (atovaquone/proguanil) works best when the amount of drug in your body is kept at a constant level. Therefore, take Malarone (atovaquone/proguanil) at evenly spaced intervals. To help you remember, take it at the same time each day for the entire prescribed time.
Do not take more or less of Malarone (atovaquone/proguanil) than prescribed. Do not stop taking Malarone (atovaquone/proguanil) before completing the full treatment unless directed to do so by your doctor, even if you feel better or do not feel sick. Skipping or changing your dose without approval from your doctor may cause prevention treatment to be ineffective, cause the amount of parasite to increase during treatment of a malaria attack, make the infection more difficult to treat (resistant), or worsen side effects.
No drug treatment is completely effective in preventing malaria. Seek immediate medical attention if you develop symptoms of malaria (e.g., fever, chills, headache, other flu-like symptoms), especially for 2 months after completing this prescription.
It is important to prevent mosquito bites (e.g., using appropriate insect repellents, wearing clothes that cover most of the body, remaining in air-conditioned or well-screened areas, using mosquito nets, using insect-killing sprays). Buy insect repellent before traveling. The most effective insect repellents contain diethyltoluamide (DEET). Ask your doctor or pharmacist to recommend an appropriate strength of mosquito repellant for you/your children.
IMPORTANT NOTE: The preceding information is intended to heighten awareness of health information and does not suggest diagnosis or treatment. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
The side effects are usually less severe for the dose used to prevent malaria than the higher dose used to treat attacks of malaria.
Side effects may include nausea, vomiting, abdominal pain, headache, diarrhea, weakness, loss of appetite, and dizziness. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
Remember that your doctor has prescribed Malarone (atovaquone/proguanil) because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using Malarone (atovaquone/proguanil) do not have serious side effects.
Tell your doctor immediately if this unlikely but serious side effect occurs: sensitivity to sunlight (easily sunburned).
Tell your doctor immediately if any of these rare but very serious side effects occur: signs of serious liver problems (e.g., persistent/severe nausea and vomiting, abdominal pain, unexplained tiredness, dark urine, yellowing eyes/skin), signs of anemia (e.g., worsening tiredness, rapid breathing, pale skin/lips/nails, fast heartbeat while resting), signs of severe infection (e.g., high fever, severe chills, body aches, sore throat).
A very serious allergic reaction to Malarone (atovaquone/proguanil) is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching, swelling, severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
Click HERE to learn more about Malarone side effects.
IMPORTANT NOTE: The preceding information is intended to heighten awareness of health information and does not suggest diagnosis or treatment. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
If you miss a dose of Malarone (atovaquone/proguanil), take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
IMPORTANT NOTE: The preceding information is intended to heighten awareness of health information and does not suggest diagnosis or treatment. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.
Malarone (atovaquone/proguanil) should not be used with the following medication because very serious interactions may occur: penicillamine.
If you are currently using the medication listed above, tell your doctor or pharmacist before starting Malarone (atovaquone/proguanil).
Before using Malarone (atovaquone/proguanil), tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: tetracycline, metoclopramide, rifampin, rifabutin.
This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
IMPORTANT NOTE: The preceding information is intended to heighten awareness of health information and does not suggest diagnosis or treatment. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.