Before taking Pradaxa (Dabigatran) 150mg, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using Pradaxa (Dabigatran) 150mg, tell your doctor or pharmacist your medical history, especially of: mechanical heart valve, kidney disease, bleeding problems (such as bleeding of the stomach/intestines, bleeding in the brain), blood disorders (such as anemia, hemophilia, thrombocytopenia), liver disease, recent major injury/surgery, stroke, frequent falls/injuries.
It is important that all your doctors and dentists know that you take Pradaxa (Dabigatran) 150mg. Before having surgery or any medical/dental procedures, tell your doctor or dentist that you are taking Pradaxa (Dabigatran) 150mg and about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Your doctor may tell you to stop Pradaxa (Dabigatran) 150mg before surgery. Follow your doctor's directions carefully.
Avoid getting injections into the muscles. If you must have an injection into the muscle (for example, a flu shot), ask for it to be given in the arm. This way, it will be easier to check for bleeding and/or apply pressure bandages.
Pradaxa (Dabigatran) 150mg may cause stomach bleeding. Daily use of alcohol while using this medicine may increase your risk for stomach bleeding. Limit or avoid alcoholic beverages.
Pradaxa (Dabigatran) 150mg can cause heavy bleeding. To lower the chance of getting cut, bruised, or injured, use caution with sharp objects like razors and nail cutters, and avoid activities such as contact sports. Use an electric razor when shaving and a soft toothbrush when brushing your teeth. If you fall or injure yourself, especially if you hit your head, call your doctor right away. Your doctor may need to check you.
Older adults may be at greater risk for bleeding while using Pradaxa (Dabigatran) 150mg.
During pregnancy, Pradaxa (Dabigatran) 150mg should be used only when clearly needed. Discuss the risks and benefits with your doctor.
It is unknown if Pradaxa (Dabigatran) 150mg passes into breast milk. Consult your doctor before breast-feeding.
See also How To Use section.
Store at room temperature away from light and moisture. Do not store in the bathroom. Open only one bottle at a time, and once the bottle is opened, the medication must be thrown away after 4 months. If your capsules are in a blister package, then keep the capsules in the blister package until you are ready to take the medication. Keep all medications away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
Pradaxa (Dabigatran) 150mg is used to prevent blood clots from forming because of a certain type of irregular heartbeat (atrial fibrillation). Preventing these blood clots helps to reduce the risk of a stroke. Pradaxa (Dabigatran) 150mg is an anticoagulant that works by blocking a certain substance (a type of clotting protein called thrombin) in your blood.
Pradaxa (Dabigatran) 150mg should not be used to prevent blood clots from forming after mechanical heart valve replacements. If you had heart valve surgery, talk to your doctor about the best medication for you. Do not stop taking any medication, including Pradaxa (Dabigatran) 150mg, without talking to your doctor first.
See also Warning section.
Read the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist before you start taking Pradaxa (Dabigatran) 150mg and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
Take Pradaxa (Dabigatran) 150mg by mouth with or without food as directed by your doctor. Swallow the capsules whole. Do not crush, chew, or break open the capsules. Doing so can release all of the drug at once, increasing the risk of side effects. Do not put Pradaxa (Dabigatran) 150mg in a pill box or medication reminder box. It must be kept tightly closed in the original bottle (or blister package) to protect it from moisture. See also Storage section for more important details.
Pradaxa (Dabigatran) 150mg is usually taken once a day to prevent clots after surgery or twice a day to prevent clots from irregular heartbeat (atrial fibrillation). Avoid antacids within 24 hours after surgery, or Pradaxa (Dabigatran) 150mg may not work as well. It is very important to take it exactly as directed. Do not increase the dose, take it more frequently, or stop taking it unless directed by your doctor.
The dosage is based on your medical condition, kidney function, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
Use Pradaxa (Dabigatran) 150mg regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day.
See also Warning section.
Easy bruising or minor bleeding (such as nosebleed, bleeding from cuts) may occur. If either of these effects persists or worsens, tell your doctor or pharmacist promptly.
Remember that your doctor has prescribed Pradaxa (Dabigatran) 150mg because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using Pradaxa (Dabigatran) 150mg do not have serious side effects.
Pradaxa (Dabigatran) 150mg can cause serious bleeding if it affects your blood clotting proteins too much. Tell your doctor right away if you have any signs of serious bleeding, including: unusual pain/swelling/discomfort, unusual/easy bruising, prolonged bleeding from cuts or gums, persistent/frequent nosebleeds, unusually heavy/prolonged menstrual flow, pink/dark urine, coughing up blood, vomit that is bloody or looks like coffee grounds, severe headache, dizziness/fainting, unusual or persistent tiredness/weakness, bloody/black/tarry stools.
Tell your doctor right away if you have any serious side effects, including: stomach/abdominal pain, severe heartburn/nausea/vomiting.
Get medical help right away if you have any very serious signs of bleeding, including: vision changes, confusion, slurred speech, weakness on one side of the body.
A very serious allergic reaction to Pradaxa (Dabigatran) 150mg is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Click here to view a more detailed list of Pradaxa side effects.
If you miss a dose of Pradaxa (Dabigatran) 150mg, take it as soon as you remember. If it is less than 6 hours until the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
Some products that may interact with Pradaxa (Dabigatran) 150mg include: mifepristone, other drugs that can cause bleeding/bruising (including antiplatelet drugs such as clopidogrel, "blood thinners" such as warfarin or enoxaparin).
Other medications can affect the removal of Pradaxa (Dabigatran) 150mg from your body, which may affect how Pradaxa (Dabigatran) 150mg works. Examples include dronedarone, ketoconazole, rifampin, and St. John's wort, among others.
Aspirin, aspirin-like drugs (salicylates), and nonsteroidal anti-inflammatory drugs (NSAIDs such as ibuprofen, naproxen, celecoxib) may have effects similar to Pradaxa (Dabigatran) 150mg. These drugs may increase the risk of bleeding problems if taken during treatment with Pradaxa (Dabigatran) 150mg. Carefully check all prescription/nonprescription product labels (including drugs applied to the skin such as pain-relieving creams) since the products may contain NSAIDs or salicylates. Talk to your doctor about using a different medication (such as acetaminophen) to treat pain/fever. If you have been prescribed low-dose aspirin and related drugs (such as clopidogrel, ticlopidine) for specific medical reasons such as heart attack or stroke prevention, ask your doctor if you should continue taking them or if your prescription should be changed. Consult your doctor or pharmacist for more details.