See also Warning section.
Before taking Tasmar (tolcapone), tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.
Tasmar (tolcapone) should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: liver problems, history of a certain muscle problem (rhabdomyolysis), fever and confusion caused by any drug.
Before using Tasmar (tolcapone), tell your doctor or pharmacist your medical history, especially of: alcoholism, low blood pressure, severe kidney problems, Parkinson's with severe movement problems.
To avoid dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.
Tasmar (tolcapone) may make you dizzy or drowsy. Use caution while driving, using machinery, or doing any activity that requires alertness. Avoid alcoholic beverages.
Caution is advised when using Tasmar (tolcapone) in the elderly because they may be more sensitive to the effects of the drug, especially drowsiness and confusion.
During pregnancy, Tasmar (tolcapone) should be used only when clearly needed. Discuss the risks and benefits with your doctor.
It is not known if Tasmar (tolcapone) passes into breast milk. Consult your doctor before breast-feeding.
IMPORTANT NOTE: The preceding information is intended to heighten awareness of health information and does not suggest diagnosis or treatment. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Store at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.
Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.
IMPORTANT NOTE: The preceding information is intended to heighten awareness of health information and does not suggest diagnosis or treatment. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Take Tasmar (tolcapone) by mouth with or without food, usually 3 times daily or as directed by your doctor. You will start on a lower dose. Your doctor may increase your dosage after 3 weeks if he or she thinks that you will benefit from the higher dose.
Dosage of Tasmar (tolcapone) is based on your medical condition and response to therapy.
Use Tasmar (tolcapone) regularly to get the most benefit from it. To help you remember, take it at the same times each day. Do not suddenly stop taking Tasmar (tolcapone) unless instructed to do so by your doctor. Doing so may cause your Parkinson's symptoms to become much worse.
Inform your doctor if your condition persists or worsens (e.g., your Parkinson's symptoms are not controlled).
IMPORTANT NOTE: The preceding information is intended to heighten awareness of health information and does not suggest diagnosis or treatment. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Nausea/vomiting, increased abnormal/uncontrolled/fast movements, dizziness upon standing, fainting, headache, sleepiness, trouble sleeping, increased number of dreams, abnormal sweating, tiredness, muscle cramps, dry mouth, constipation, gas, and abdominal pain may occur. Diarrhea may occur between 2-12 weeks after you start the medication. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
Remember that your doctor has prescribed Tasmar (tolcapone) because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using Tasmar (tolcapone) may develop serious side effects, but with frequent visits to your doctor, this risk can be minimized.
Your urine may change color (e.g., increased yellow color). This effect is harmless.
Tell your doctor immediately if any of these unlikely but serious side effects occur: mental/mood changes (e.g., confusion, hallucinations, depression, hostility, nervousness), fever, muscle stiffness, problems urinating, lower/mid-back pain, uncontrolled urination, fast/irregular heartbeat.
Tell your doctor immediately if any of these rare but very serious side effects occur: easy bleeding/bruising, sore/painful/weak muscles, breathing problems, cough, pain with breathing.
A very serious allergic reaction to Tasmar (tolcapone) is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching, swelling, severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
Click HERE to learn more about Tasmar side effects.
IMPORTANT NOTE: The preceding information is intended to heighten awareness of health information and does not suggest diagnosis or treatment. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
If you miss a dose of Tasmar (tolcapone), take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
IMPORTANT NOTE: The preceding information is intended to heighten awareness of health information and does not suggest diagnosis or treatment. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.
Tasmar (tolcapone) should not be used with the following medications because very serious interactions may occur: certain MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, tranylcypromine).
If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting Tasmar (tolcapone).
Before using Tasmar (tolcapone), tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: isoproterenol, epinephrine, norepinephrine, dopamine, dobutamine, methyldopa, apomorphine, isoetharine, bitolterol, probenecid, cholestyramine, erythromycin, rifampicin, ampicillin, chloramphenicol.
Tell your doctor or pharmacist if you also take drugs that may cause drowsiness or lower your blood pressure such as: antihistamines that cause drowsiness (e.g., diphenhydramine), anti-anxiety drugs (e.g., diazepam), anti-seizure drugs (e.g., carbamazepine), medicine for sleep (e.g., sedatives, hypnotics), muscle relaxants, other narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., phenothiazines such as chlorpromazine, tricyclics such as amitriptyline), tranquilizers.
This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
IMPORTANT NOTE: The preceding information is intended to heighten awareness of health information and does not suggest diagnosis or treatment. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.