Before taking Tolvaptan 15mg, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using Tolvaptan 15mg, tell your doctor or pharmacist your medical history, especially of: diabetes, liver disease, inability to make urine (anuria), use/abuse of alcohol.
To prevent loss of too much body water (dehydration) while taking Tolvaptan 15mg, you must be able to replace fluids by drinking. Before taking Tolvaptan 15mg, tell your doctor if you are not able to drink normally or if you cannot feel if you are thirsty. (See also How to Use section.)
Tolvaptan 15mg may infrequently make your blood sugar level rise, which can cause or worsen diabetes. If you have diabetes, be sure to check your blood sugar regularly. Your doctor may need to adjust your diabetes medication, exercise program, or diet.
During pregnancy, Tolvaptan 15mg should be used only when clearly needed. Discuss the risks and benefits with your doctor.
It is unknown if Tolvaptan 15mg passes into breast milk. Consult your doctor before breast-feeding.
Store at room temperature between 59-86 degrees F (15-30 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your medication.
Tolvaptan 15mg is used to treat low levels of salt (sodium) in the blood, which can result from conditions such as heart failure and certain hormone imbalances. Tolvaptan 15mg belongs to a class of drugs known as vasopressin receptor antagonists. It works by increasing the amount of urine you make, causing your body to get rid of extra water. This helps to slowly increase to normal levels of salt (sodium) in the blood.
Read the Medication Guide provided by your pharmacist before you start using Tolvaptan 15mg and each time you get a refill. If you have any questions, consult your doctor or pharmacist.
Take Tolvaptan 15mg by mouth with or without food, usually once daily or as directed by your doctor. You should not take Tolvaptan 15mg for longer than 30 days.
To prevent losing too much body water (dehydration), have water available to drink at all times while taking Tolvaptan 15mg. Drink when you are thirsty unless otherwise directed by your doctor.
Use Tolvaptan 15mg regularly to get the most benefit from it. To help you remember, take it at the same time each day. Do not stop and restart Tolvaptan 15mg on your own. You may need to go back to a hospital to restart Tolvaptan 15mg. Tell your doctor immediately if you stop taking Tolvaptan 15mg for any reason.
Avoid eating grapefruit or drinking grapefruit juice while using Tolvaptan 15mg unless your doctor instructs you otherwise. Grapefruit can increase the amount of Tolvaptan 15mg in your bloodstream. Consult your doctor or pharmacist for more details.
Dosage of Tolvaptan 15mg is based on your medical condition and response to treatment.
Thirst, dry mouth, loss of appetite, constipation, or weakness may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
Remember that your doctor has prescribed Tolvaptan 15mg because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using Tolvaptan 15mg do not have serious side effects.
Loss of too much body water (dehydration) can occur. The risk is increased if you have persistent vomiting or diarrhea, and cannot drink normally. Contact your doctor immediately if you notice any symptoms of dehydration, such as fast heartbeat or dizziness/lightheadedness.
People with severe liver disease (cirrhosis) may have increased risk of bleeding from the stomach or intestines while taking Tolvaptan 15mg. Tell your doctor immediately if you have any of the following symptoms: black/bloody stools, vomit that contains blood or looks like coffee grounds.
Tolvaptan 15mg may rarely cause serious (possibly fatal) liver disease. Get medical help right away if you have any symptoms of liver damage, including: dark urine, persistent nausea/vomiting/loss of appetite, stomach/abdominal pain, yellowing eyes/skin.
A very serious allergic reaction to Tolvaptan 15mg is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Click here to view a more detailed list of Tolvaptan side effects.
If you miss a dose of Tolvaptan 15mg, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
See also How to Use section.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
A product that may interact with Tolvaptan 15mg is: desmopressin.
Other medications can affect the removal of Tolvaptan 15mg from your body, which may affect how Tolvaptan 15mg works. Examples include azole antifungals (such as ketoconazole), HIV protease inhibitors (such as lopinavir, ritonavir), macrolide antibiotics (such as erythromycin), rifamycins (such as rifabutin), St. John's Wort, drugs used to treat seizures (such as carbamazepine, phenytoin), among others.
Treatment with Tolvaptan 15mg should be started or restarted in a hospital for proper monitoring. Too rapid correction of low levels of sodium in the blood may rarely result in a serious (rarely fatal) condition - osmotic demyelination syndrome (ODS). Tell your doctor immediately if you notice any of the following symptoms of ODS: trouble speaking/swallowing, mental/mood changes (such as confusion), weakness/involuntary movement in the arms/legs, or seizures.