See also How to Use and Warning Sections
Before taking Wellbutrin SR (bupropion) 200mg, tell your doctor or pharmacist if you are allergic to it or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Wellbutrin SR (bupropion) 200mg should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: seizures, eating disorders (e.g., bulimia, anorexia nervosa).
Wellbutrin SR (bupropion) 200mg should not be used if you are suddenly stopping regular use of sedatives (e.g., benzodiazepines such as lorazepam) or alcohol, which can cause a higher risk of seizures.
Before using Wellbutrin SR (bupropion) 200mg, tell your doctor or pharmacist your medical history, especially of: personal or family history of psychiatric disorder (e.g., bipolar/manic-depressive disorder), personal or family history of suicide thoughts/attempts, head injury, brain tumor, liver problems, heart problems, high blood pressure, kidney problems, diabetes, alcohol/drug dependence, intention to quit smoking.
Wellbutrin SR (bupropion) 200mg may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely.
Limit or avoid consumption of alcoholic beverages. Alcohol can increase your risk of dizziness and seizures.
Do not take this medicine with any other product containing Wellbutrin SR (bupropion) 200mg (e.g., drugs to help quit smoking) since large doses of Wellbutrin SR (bupropion) 200mg are more likely to cause seizures.
Kidney function declines as you grow older. Wellbutrin SR (bupropion) 200mg is removed by the kidneys. Therefore, elderly people may be more sensitive to Wellbutrin SR (bupropion) 200mg and to side effects.
Wellbutrin SR (bupropion) 200mg should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. Infrequently, newborns whose mothers have used certain newer antidepressants during the last 3 months of pregnancy may develop symptoms including persistent feeding or breathing difficulties, jitteriness, seizures or constant crying. Promptly report any such symptoms to the doctor. However, do not stop taking Wellbutrin SR (bupropion) 200mg unless your doctor directs you to do so.
Wellbutrin SR (bupropion) 200mg passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.
Store at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture. Wellbutrin SR (bupropion) 200mg tablets may have a strange odor. This is normal and the medication is still okay to use. Do not store in the bathroom. Keep all medicines away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.
Read the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist before you start using Wellbutrin SR (bupropion) 200mg and each time you get a refill. If you have any questions regarding the information, consult your doctor or pharmacist.
Take Wellbutrin SR (bupropion) 200mg by mouth, usually twice daily with or without food. If nausea occurs, you may take Wellbutrin SR (bupropion) 200mg with food. It is important to take your doses at least 8 hours apart or as directed by your doctor to decrease your risk of having a seizure.
Do not crush or chew Wellbutrin SR (bupropion) 200mg. Doing so can release all of the drug at once, increasing the risk of side effects, including seizures. Also, do not split the tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing.
You may have trouble sleeping when you start taking Wellbutrin SR (bupropion) 200mg. Do not take your evening dose too close to bedtime. Let your doctor know if sleeplessness becomes a problem.
Your dosage is based on your medical condition and response to therapy. Your dose should be slowly increased to limit side effects such as sleeplessness and decrease the risk of seizures.
Do not take more or less medication than prescribed. Taking more than the recommended dose will increase your risk of having a seizure. The usual maximum dose is 300-400 milligrams per day (maximum single dose 150-200 milligrams).
Do not stop taking Wellbutrin SR (bupropion) 200mg without notifying your doctor. Use Wellbutrin SR (bupropion) 200mg regularly in order to get the most benefit from it. Remember to use Wellbutrin SR (bupropion) 200mg at the same time each day.
It may take 4 weeks or more before the full effects of Wellbutrin SR (bupropion) 200mg are noticed. Talk to your doctor if your condition persists or worsens.
See also the Warning section.
Dry mouth, sore throat, nausea, vomiting, stomach/abdominal pain, flushing, headache, loss of appetite, constipation, trouble sleeping, increased sweating, strange taste in mouth, muscle/joint aches, dizziness, or blurred vision may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.
Remember that your doctor has prescribed Wellbutrin SR (bupropion) 200mg because he or she has judged that the benefit to you is greater than the risk of side effects. Many people do not have serious side effects.
Tell your doctor immediately if any of these unlikely but serious side effects occur: fainting, chest pain, fast heartbeat, severe headache, uncontrolled movements (tremor), unusual weight loss or gain, ringing in the ears, mental/mood changes (e.g., agitation, anxiety, hallucinations, nervousness, confusion, restlessness).
Tell your doctor immediately if any of these rare but very serious side effects occur: muscle pain/tenderness/weakness, change in the amount of urine.
Wellbutrin SR (bupropion) 200mg may rarely cause seizures. Seek immediate medical attention if you have a seizure while taking Wellbutrin SR (bupropion) 200mg. If you have a seizure while taking Wellbutrin SR (bupropion) 200mg, you should not take Wellbutrin SR (bupropion) 200mg again.
A severe allergic reaction to Wellbutrin SR (bupropion) 200mg is unlikely, but seek immediate medical attention if it occurs. Symptoms of a severe allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
An empty tablet shell may appear in your stool. This is harmless.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Click here to view a more detailed list of Wellbutrin SR side effects.
If you miss a dose of Wellbutrin SR (bupropion) 200mg, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up. Taking too much of Wellbutrin SR (bupropion) 200mg can increase your chance of having a seizure.
The effects of some drugs can change if you take other drugs or herbal products at the same time. This can increase your risk for serious side effects or may cause your medications not to work correctly. These drug interactions are possible, but do not always occur. Your doctor or pharmacist can often prevent or manage interactions by changing how you use your medications or by close monitoring.
To help your doctor and pharmacist give you the best care, be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products) before starting treatment with this product. While using this product, do not start, stop, or change the dosage of any other medicines you are using without your doctor's approval.
Some products that may interact with Wellbutrin SR (bupropion) 200mg include: amantadine, diabetes medications (such as glyburide, glipizide, or insulin), certain x-ray dyes (including iomeprol), levodopa, nicotine products (such as patches, gum, or spray), regular use of sedatives (such as alprazolam), stimulants, tamoxifen, warfarin.
Avoid taking MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine) during treatment with Wellbutrin SR (bupropion) 200mg and for two weeks before and after treatment. In some cases a serious (possibly fatal) drug interaction may occur.
Other medications can affect the removal of Wellbutrin SR (bupropion) 200mg from your body, which may affect how Wellbutrin SR (bupropion) 200mg works. Examples include cyclophosphamide, orphenadrine, thiotepa, antiplatelet drugs (including clopidogrel, ticlodipine), anti-seizure drugs (such as carbamazepine, phenobarbital, phenytoin), HIV drugs (such as efavirenz, ritonavir), rifamycins (such as rifampin), among others.
Wellbutrin SR (bupropion) 200mg can speed up the removal of other drugs from your body, which may affect how they work. Examples of affected drugs include citalopram, antiarrhythmics (such as propafenone, flecainide), antidepressants (such as desipramine, paroxetine, fluoxetine, sertraline), antipsychotics (such as haloperidol, thioridazine), beta-blockers (such as metoprolol), among others.
Also report the use of drugs which might increase seizure risk (decrease seizure threshold) when combined with Wellbutrin SR (bupropion) 200mg, such as antipsychotics (e.g., chlorpromazine), tricyclic antidepressants (e.g., amitriptyline), corticosteroids (e.g., prednisone) or theophylline, among others. Consult your doctor or pharmacist for details.
Large amounts of caffeine and other stimulants, such as those found in weight loss and cold/sinus medications, can increase the chance of seizures with Wellbutrin SR (bupropion) 200mg. Check all nonprescription/prescription/herbal drug labels for caffeine and other stimulants (e.g., ephedra). Consult your doctor or pharmacist.
Wellbutrin SR (bupropion) 200mg may interfere with certain laboratory tests, possibly causing false test results. Make sure laboratory personnel and all your doctors know you use Wellbutrin SR (bupropion) 200mg.
This document does not contain all possible drug interactions. Keep a list of all the products you use. Share this list with your doctor and pharmacist to lessen your risk for serious medication problems.
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