Before taking Xenical (Orlistat) 120mg, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using Xenical (Orlistat) 120mg, tell your doctor or pharmacist your medical history, especially of: a certain digestive problem (chronic malabsorption syndrome), a certain gall bladder problem (cholestasis), underactive thyroid (hypothyroidism), kidney stones/problems (such as calcium oxalate kidney stones, hyperoxaluria), certain eating disorders (anorexia nervosa/bulimia).
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
If you are diabetic, weight loss may improve your blood sugar control. Be sure to check your blood sugar regularly and tell your doctor the results. Your doctor may need to adjust your diabetes medication, exercise program, or diet.
Xenical (Orlistat) 120mg must not be used during pregnancy. Weight loss offers no potential benefit to a pregnant woman and may harm an unborn baby. If you become pregnant or think you may be pregnant, tell your doctor immediately.
It is unknown if Xenical (Orlistat) 120mg passes into breast milk. Consult your doctor before breast-feeding.
Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.
Xenical (Orlistat) 120mg is used along with a doctor-approved reduced-calorie diet, exercise, and behavior modification program to help significantly overweight (obese) persons lose weight. Taking Xenical (Orlistat) 120mg can also help prevent you from regaining the weight you have lost. Losing weight and keeping it off can reduce the many health risks that obesity causes, including heart disease, diabetes, high blood pressure, some forms of cancer, certain breathing problems, and a shorter life span.
Dietary fats need to be broken down into smaller pieces before the body can absorb them. Xenical (Orlistat) 120mg works by blocking the enzyme that breaks down fats in your diet. This undigested fat then passes out of your body in your bowel movement. Xenical (Orlistat) 120mg does not block the absorption of calories from sugar and other non-fat foods, so you still need to restrict your total intake of calories.
If you are taking the over-the-counter product to self-treat, read all directions on the product package before taking Xenical (Orlistat) 120mg.
If your doctor has prescribed Xenical (Orlistat) 120mg, read the Patient Information Leaflet if available from your pharmacist before you start taking Xenical (Orlistat) 120mg and each time you get a refill. Take Xenical (Orlistat) 120mg as directed by your doctor, by mouth with liquid sometime during each meal that contains fat or within 1 hour after the meal, usually 3 times daily. If you miss a meal or your meal contains no fat, skip that dose of the medication. To decrease the chance of unpleasant side effects, it is very important that no more than 30% of the calories in your diet come from fat. Your daily intake of fat, protein, and carbohydrates should be evenly spread over 3 main meals.
Do not increase your dose or use Xenical (Orlistat) 120mg more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase.
Because Xenical (Orlistat) 120mg can interfere with the absorption of certain vitamins (fat-soluble vitamins including A, D, E, K), a daily multivitamin supplement containing these nutrients is recommended. Take the multivitamin at least 2 hours before or 2 hours after taking Xenical (Orlistat) 120mg (such as at bedtime).
If you take cyclosporine, take it at least 3 hours before or after Xenical (Orlistat) 120mg to make sure the full dose of cyclosporine is absorbed into your bloodstream. If you take levothyroxine, take it at least 4 hours before or after Xenical (Orlistat) 120mg.
You should see some weight loss within 2 weeks after you start Xenical (Orlistat) 120mg. Tell your doctor if your condition does not improve or if it worsens.
Changes in your bowel function often occur because of the unabsorbed fat. Fatty/oily stool, oily spotting, intestinal gas with discharge, a feeling of needing to have a bowel movement right away, increased number of bowel movements, or poor bowel control may occur. These side effects may get worse if you eat more fat than you should. If these effects persist or worsen, notify your doctor promptly.
If your doctor has directed you to use Xenical (Orlistat) 120mg, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using Xenical (Orlistat) 120mg do not have serious side effects.
Stop taking Xenical (Orlistat) 120mg and tell your doctor immediately if any of these rare but serious side effects occur: symptoms of liver disease (such as persistent nausea/vomiting, severe stomach/abdominal pain, dark urine, yellowing eyes/skin), symptoms of kidney stones (such as back pain, pain when urinating, pink/bloody urine).
A very serious allergic reaction to Xenical (Orlistat) 120mg is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Click here to view a more detailed list of Xenical side effects.
If you miss a dose of Xenical (Orlistat) 120mg, take it as soon as you remember unless it has been more than 1-2 hours since your meal. In that case, skip the missed dose since most of the fat from your meal will already have been absorbed and the medication will not work. Do not double the dose to catch up.
See also How to Use section.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
Some products that may interact with Xenical (Orlistat) 120mg include: "blood thinners" (such as warfarin).