Archive for January, 2010

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Poorly-controlled childhood asthma common despite consistent ICS use

Sunday, January 31st, 2010

Source: MedWire News
Many children with mild-to-moderate asthma do not achieve good control of their disease despite consistent use of inhaled corticosteroids (ICS), researchers have found.
Writing in the Annals of Asthma, Allergy and Immunology, Gregory Sawicki (Children’s Hospital Boston, Massachusetts, USA) and team explain: “Daily controller medication use is recommended for children with persistent asthma to achieve [...]

Big Pharma’s Practice of Charging Too Much for Drugs Continues

Friday, January 29th, 2010

Judge rules nine drugmakers overcharged New York City, counties for medicines.
Bloomberg News (1/29, O’Reilly) reports, “Merck & Co., Pfizer Inc., and seven other drugmakers overcharged New York City and 42 New York counties for medicines and may be liable for damages in millions of dollars in drug sales, a federal judge [...]

Intranasal steroids best for reducing hayfever nasal symptoms

Wednesday, January 27th, 2010

Treatment with intranasal steroids (INSs) produces the greatest reductions in nasal symptoms among patients with seasonal allergic rhinitis, results of a systematic review show.
Writing in the Annals of Asthma, Allergy and Immunology, Michael Benninger (Cleveland Clinic, Ohio, USA) and team explain that guidelines on the management of allergic rhinitis emphasize the importance of targeting nasal airway [...]

Aggressive statin therapy significantly improves endothelial function in CVD

Monday, January 25th, 2010

Source: MedWire News
Researchers report that aggressive lipid-lowering therapy may be better for endothelial function than less aggressive therapy in patients with cardiovascular disease (CVD).
Previous studies have demonstrated that statins, and the reduction in low-density lipoprotein cholesterol (LDL) cholesterol levels they bring about, improve clinical outcomes in patients with CVD.
Accordingly, guidelines in the EU and USA [...]

Heart Risk in One-Fifth of U.S. Teenagers Found by Lipid Tests

Thursday, January 21st, 2010

A risk of heart disease in one-fifth of U.S. teenagers was identified through tests of lipids in the blood, showing the importance of diet, exercise and screening, according to U.S. researchers.
Obese children were at the highest danger of abnormal lipid levels, with 43 percent testing outside the recommended ranges, according to today’s report by the U.S. Centers [...]

A third of BD patients receive inadequate maintenance treatment

Wednesday, January 20th, 2010

Source: MedWire News
Over one-third of bipolar disorder (BD) patients do not receive adequate provision or continuity of maintenance treatment during their first follow-up maintenance phase, indicate study findings.
Studies investigating maintenance treatment in BD have lacked agreement on how the longitudinal treatment phases should be defined, thus presenting inconsistent results.
Erkki Isometsä (Helsinki University Central Hospital, Finland) [...]

Certain antihypertensives may be associated with lower a-fib risk than other drugs.

Wednesday, January 20th, 2010

Source: DIA Daily
MedPage Today (1/19, Walsh) reported that “hypertensive patients treated with angiotensin-converting enzyme (ACE) inhibitors, angiotensin II-receptor blockers (ARBs), or beta-blockers have a lower risk for atrial fibrillation than those treated with calcium channel blockers,” according to research published in the Annals of Internal Medicine. Researchers found that, “compared [...]

Tailored statin treatment more effective for CAD prevention than treat-to-target

Tuesday, January 19th, 2010

Source: MedWire News
A tailored statin treatment strategy based on the individual patients needs is more effective for preventing coronary artery disease (CAD)-related events than treating to low-density lipoprotein (LDL) cholesterol targets, report researchers.
Rodney Hayward (University of Michigan Medical School, Ann Arbor, USA) and colleagues carried out a population level simulation using data from participants of [...]

Mail-order pharmacies deliver greater adherence

Tuesday, January 19th, 2010

Source: Pharmacy News
Patients who use mail-order pharmacies are more likely to have good medication adherence than patients who use local pharmacies, a US study has found.
Published in The American Journal of Managed Care, the study investigated the likelihood of good adherence to newly prescribed antiglycemic, antihypertensive, and lipid-lowering medications among 13,922 diabetic patients in California.
It found that compared [...]

Secondary prevention adherence falls rapidly after stroke

Monday, January 18th, 2010

Source: MedWire News
Many patients stop taking secondary prevention drugs within just 2 years after suffering a stroke, show results from a large Swedish study.
“To prevent new cardiovascular events after stroke, preventive drugs should be used continuously,” said lead researcher Eva-Lotta Glader (Umeå University Hospital, Sweden). “Yet the proportion of patients who were persistent users of [...]

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