Archive for August, 2010

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Report: Seniors Face Drug Cost Spikes.

Monday, August 30th, 2010

Source: DIA Daily

BusinessWeek /HealthDay (8/26) reported, “In 2009, the prices of the most popular brand-name drugs used by American seniors rose 8.3 percent, according to AARP researchers who looked at 217 brand-name drugs. They also noted that the price of those medications increased seven percent in 2008, and that the retail price [...]

Reduced Plavix Efficacy Associated With Specific Gene Variants Confirmed In Two New Analyses, But Not In A Third.

Monday, August 30th, 2010

Source: DIA Daily

The Wall Street Journal (8/30, Winslow) reports that for patients with acute coronary syndrome, physicians often turn to Sanofi-Aventis and Bristol-Myers Squibb’s Plavix (clopidogrel) to prevent clot-induced strokes and heart attacks. However, a significant number of patients carry genetic variations that impede the drug’s effectiveness. While some believe [...]

High intake of green leafy vegetables lowers Type 2 diabetes risk

Friday, August 20th, 2010

Source: MedWire News
A high consumption of green leafy vegetables, such as spinach, kale, and lettuce, significantly reduces the risk for developing Type 2 diabetes, results from a systematic review and meta-analysis suggest.
“The findings add to the growing body of evidence that lifestyle is key for the prevention of Type 2 diabetes,” lead study author Patrice [...]

Modest fat gain affects blood vessel function

Friday, August 20th, 2010

Source: MedWire News
Gaining modest amounts of fat causes endothelial dysfunction in normal-weight adults even if their blood pressure does not change, a study suggests.
Endothelial function was only impaired with increases in visceral and not subcutaneous fat, and normal blood vessel function was recovered after the fat was lost again, the researchers report.
“Our study provides evidence [...]

Untreated psychosis duration predicts non-remission

Thursday, August 19th, 2010

Source: MedWire News
Duration of untreated psychosis (DUP) predicts short- and long-term failure to achieve remission in first-episode psychosis patients, researchers have found.
“Non-remission of positive psychotic symptoms is quite common in first-episode, non-affective psychosis,” explain Erik Simonsen (University of Copenhagen, Denmark) and team.
To investigate factors associated with failure to achieve remission in first-episode psychosis, the researchers [...]

Anti-inflammatory effects of HDL revealed

Thursday, August 19th, 2010

High-density lipoprotein (HDL) particles interfere with the binding of T-cell microparticles (MPs) to human monocytes, new research suggests.
The net result is to inhibit the production of pro-inflammatory cytokines, meaning this is one mechanism by which HDL cholesterol exerts an anti-inflammatory effect.
The findings are reported by an Italian team in the open-access journal PLoS One.
Rakel Carpintero (University [...]

HRT breast cancer risk varies by personal characteristics

Wednesday, August 18th, 2010

Source: MedWire News
Breast cancer risk increases with increasing duration of hormone replacement therapy (HRT), with continuous combined estrogen-progestin therapy (EPT) users at the greatest risk for developing the disease, researchers report.
Women need detailed information regarding the risks associated with HRT to optimize their own risk-benefit assessments, say Giske Ursin (University of Oslo, Norway) and colleagues.
In [...]

Bills would ban drugmaker deals to delay cheap drugs

Wednesday, August 18th, 2010

Source: USA Today
Generic-drug makers in the past year have dropped a record number of patent lawsuits against brand-name pharmaceutical companies in exchange for compensation to delay getting money-saving drugs to market.
Legislation that has recently gained momentum in Congress threatens to end such deals.
The House has passed a bill limiting “pay for delay” settlements, and the [...]

Pill May Be Linked To Increases In Certain Brain Areas.

Wednesday, August 18th, 2010

Source: DIA Daily

The UK Telegraph (8/18, Jamieson) reports that after taking “high-resolution images of men, women taking the pill, and women not taking the pill,” Austrian researchers found the “contraceptive of choice of an estimated 3.5 million British women — a quarter of all 16 to 49-year-olds — increases the size of [...]

Low HDL, high triglycerides contribute to residual CHD risk

Tuesday, August 17th, 2010

Source: MedWire News
High levels of triglycerides and low levels of high-density lipoprotein (HDL) cholesterol have a “strong and synergistic” influence on coronary heart disease (CHD) risk in the presence of well-controlled low-density lipoprotein (LDL) cholesterol, US scientists believe.
Vincent Carey (Brigham and Women’s Hospital, Boston, Massachusetts) and colleagues sought to quantify the relative contributions of triglycerides [...]

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