Archive for November, 2010

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Statins reduce CVD risk in Chinese Type 2 diabetes patients by up to 50%

Friday, November 26th, 2010

Source: MedWire News
Statins can reduce the risk for cardiovascular disease (CVD) by 40-50% in Chinese patients with Type 2 diabetes, research suggests.
The study also showed that high levels of low-density lipoprotein (LDL) cholesterol and low levels of high-density lipoprotein (HDL) cholesterol predicted incident CVD. In contrast, triglycerides had no significant predictive value.
The findings come from [...]

High-protein, low-glycemic index diet aids weight maintenance in overweight adults

Thursday, November 25th, 2010

Source: MedWire News
Diets that are high in protein and low in glycemic index effectively minimize weight regain and promote further weight loss in obese patients after a successful weight-loss diet, a study suggests.
Among overweight adults who had successfully lost at least 8% of their initial body weight on a low calorie 8-week diet (800 kcal [...]

Fenofibrate may delay renal impairment progression in diabetics

Wednesday, November 24th, 2010

Source: MedWire News
Fenofibrate therapy may slow down the progression of albuminuria and glomerular filtration rate (GFR) impairment in patients with Type 2 diabetes, study results indicate.
Previous studies have reported a rise in plasma creatinine associated with fenofibrate use, and this has led to concerns over the safety of the drug.
However, Rudee Ting (University of Sydney, [...]

Lipid levels predict CHD risk in elderly patients receiving statins

Wednesday, November 24th, 2010

Source: MedWire News
In elderly patients, lipid levels are stronger predictors of coronary heart disease (CHD) among those receiving statins than those who are not receiving lipid-lowering therapy, researchers say.
Céline Straczek (Paris Descartes University, France) and colleagues show that standard lipid measures, non-high-density lipoprotein (non-HDL) cholesterol, and apolipoprotein (apo)B100 are all independent predictors of CHD among [...]

Long-term efficacy of anastazole demonstrated in breast cancer patients

Tuesday, November 23rd, 2010

Source: MedWire News
Results of the Arimidex, Tamoxifen, Alone or in Combination (ATAC) trial at 10 years confirm the long-term superiority of anastrazole over tamoxifen as initial adjuvant therapy for postmenopausal women with hormone-sensitive early breast cancer, researchers report.
The number of patients who were disease- and recurrence-free at 10-years was significantly greater in the anastrazole (n=3125) [...]

Need for more intensive treatment of dyslipidemia in Canadian patients

Tuesday, November 23rd, 2010

Source: MedWire News
Findings from the DYSlipidemia International Study (DYIS) suggest that treatment for dyslipidemia should be intensified in Canadian patients, especially among those who are at high risk.
Only 63% of all patients in the study met the low-density lipoprotein (LDL) cholesterol guideline levels, including just 55% of high-risk patients.
“The findings suggest the possibility that, in [...]

PhRMA quietly spends big in 2010

Tuesday, November 16th, 2010

The drug industry spent at least $25 million protecting its friends in Congress this year, but PhRMA chief John Castellani doesn’t really want to talk about it.
The trade group was instrumental in several close Democratic Senate contests, spending millions to successfully protect embattled Majority Leader Harry Reid and seven figures to help Sen. Patty Murray [...]

Out-of-pocket spend and dispensing limits, barriers to contraception

Tuesday, November 16th, 2010

Source: MedWire News
Women pay a substantial amount of money out-of-pocket for oral contraception (OC) and, although they are improving, dispensing limits still remain, report US researchers.
“More work needs to be done to remove any barriers that prevent women from obtaining as many pills packs as they want,” suggest Su-Ying Liang, from the University of California [...]

Diagnostic delays, poor treatment adherence linked to frequent BD episodes

Tuesday, November 16th, 2010

Source: MedWire News
Delays in diagnosis and poor treatment adherence are associated with a high frequency of mood episodes in patients with bipolar disorder (BD), research shows.
Among patients with BD, “the frequency of affective disorder (episode frequency) can range from once in lifetime to many per year,” explain Luis Gutiérrez-Rojas and colleagues from the University of [...]

Intensive statin therapy reduces CV risk

Wednesday, November 10th, 2010

Source: MedWire News
Patients at high risk for cardiovascular (CV) events may benefit from intensive lipid-lowering therapy, even if their baseline level of low-density lipoprotein (LDL) cholesterol is already less than 2 mmol/l (77.3 mg/dl), research suggests.
Writing in The Lancet, two research groups (Study of the Effectiveness of Additional Reductions in Cholesterol and Homocysteine [SEARCH] and Cholesterol [...]

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