Archive for December, 2010

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Fenofibrate therapy reduces burden of oxidative stress

Thursday, December 30th, 2010

Source: MedWire News
Treatment with fenofibrate leads to a reduction in biomarkers of oxidative stress, US researchers have shown.
Given the established role of oxidative stress in atherogenesis, the team hypothesizes that these observations “may partially explain the efficacy of fenofibrate in reducing cardiovascular events.”
Researchers led by Michael Tsai (University of Minnesota, Minneapolis, USA) measured levels of [...]

Cerebrovascular disease highly prevalent in Type 2 diabetics

Thursday, December 30th, 2010

Source: MedWire News
Atherosclerotic plaques are present in the vast majority of patients with Type 2 diabetes mellitus, a state-of-the-art imaging study has found.
The study, which used dual-source computed tomography angiography (DSCTA), also reveals that plaque in these patients is typically noncalcified, nonobstructive, and distributed extensively throughout the carotid and cerebrovascular vasculature.
Zhi-gang Yang (West China Hospital [...]

Better strategies needed to ensure osteoporosis treatment compliance

Wednesday, December 22nd, 2010

Source: MedWire News
Nearly 80% of people who are prescribed combined calcium and vitamin D (CaVitD) supplements either eventually stop taking them completely or do not take them as prescribed, Spanish research shows.
These results “reinforce the need to establish educational programs… to improve the interaction of health-care professionals with patients regarding treatment adherence,” write Camil Castelo-Branco [...]

Calcification and inflammatory markers raised in Type 2 diabetes and IHD

Monday, December 20th, 2010

Source: MedWire News
A Danish study has revealed elevated levels of calcification and inflammatory markers in patients with Type 2 diabetes and ischemic heart disease (IHD).
Serum levels of the calcification marker Matrix γ-carboxyglutamate protein (MGP) and the inflammatory markers YKL-40 and high-sensitivity C-reactive protein (hsCRP) were higher among individuals with either Type 2 diabetes or IHD, [...]

1 in 2 seniors on antidepressants face drug interactions

Monday, December 20th, 2010

Source: MSNBC/Reuters
Resulting side effects caused many to stop their prescription, new study finds
More than half of older Americans taking an antidepressant for the first time were already taking another drug that could interact with it and cause side-effects, researchers reported on Friday.
And a quarter of patients who suffered side-effects stopped taking antidepressants altogether, the study [...]

Impact of osteoporosis on quality of life underestimated by physicians

Friday, December 17th, 2010

Source: MedWire News
Physicians significantly underestimate the impact of osteoporosis on patient quality of life, results of a multinational survey show.
In spite of this, the majority of physicians willingly endorse programs that encourage better communication or education for managing osteoporosis, report René Rizzoli (Geneva University Hospitals, Switzerland) and colleagues in the Archives of Osteoporosis.
The researchers carried out [...]

Online Pharmacies, the Obama Administration and Public Health

Tuesday, December 14th, 2010

By Gabriel Levitt and Margaret Rode of PharmacyChecker.com
http://pharmacycheckerblog.com/online-pharmacies-the-obama-administration-and-public-health
The Obama administration is taking actions to address the illegal sale of counterfeit prescription drugs online. These efforts can benefit patients who could fall victim to rogue online pharmacies, but may also limit access to safe and affordable medication provided by non-U.S. international online pharmacies, many based in Canada. Millions [...]

Alzheimers disease risk decreased by high levels of HDL cholesterol

Tuesday, December 14th, 2010

Source: MedWire News
High levels of high-density lipoprotein (HDL) cholesterol may be associated with a decreased risk for Alzheimer’s disease in elderly individuals, research shows.
The team reports that high HDL cholesterol levels were associated with a 40% decreased risk for both probable and possible Alzheimer’s disease.
“In addition, higher levels of total cholesterol, non-HDL cholesterol, and low-density [...]

Metformin treatment does not adversely affect CVD risk in Type 2 diabetics

Monday, December 13th, 2010

Results from a systematic review and meta-analysis suggest that metformin treatment for Type 2 diabetes does not increase cardiovascular disease (CVD) risk and may in fact reduce it.
However, the analysis did show that concomitant use with sulfonylureas resulted in significantly reduced survival, which the researchers say “deserves further investigation.”
Edoardo Mannucci (Azienda Ospedaliero-Universitaria Careggi, Florence, Italy) [...]

Exenatide addition to insulin lowers glucose and weight in Type 2 diabetes

Thursday, December 9th, 2010

Study results show that adding exenatide to insulin glargine for the treatment of patients with uncontrolled Type 2 diabetes is effective for achieving good glycemic control and weight loss.
“This study may be the best result ever for patients whose diabetes is inadequately controlled on a combination of pills and insulin,” said study author John Buse [...]

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