Atorvastatin
Atorvastatin therapy may have antithrombotic effect in Type 1 diabetes
Wednesday, August 4th, 2010Source: MedWire News
Atorvastatin increases fibrin network permeability and may therefore have an antithrombotic effect in patients with Type 1 diabetes, a Swedish study suggests.
In the journal Thrombosis Research, Sara Tehrani, from Danderyd Hospital in Stockholm, and colleagues say: “Atorvastatin therapy potentially has antithrombotic effects that are unrelated to the lipid-lowering effects of the drug, supporting the [...]
Atorvastatin Appears To Trump Rosuvastatin In Protecting Diabetic, Nondiabetic Kidney Function.
Tuesday, July 6th, 2010Medscape (7/2, Keller) reported that new research coming out of the Netherlands has “found atorvastatin (ATV) protective and rosuvastatin (RSV) unprotective, and possibly harmful, in diabetic and nondiabetic patients.” In fact, “high-dose ATV significantly reduced proteinuria and did not affect renal function, whereas RSV was associated with a significant decline in [...]
Single-pill amlodipine/atorvastatin offers ‘rapid, significant benefits’
Tuesday, June 1st, 2010Source: MedWire News
Single-pill amlodipine/atorvastatin therapy is well tolerated and associated with significant improvements in a range of cardiovascular (CV) risk factors, study findings suggest.
The investigators say that a multifactorial approach is effective in achieving blood pressure and lipid targets, and reducing global cardiovascular risk in people with hypertension and other CV risk factors.
Richard Grimm (Berman [...]
Moderate-dose atorvastatin aids coronary regeneration after AMI
Monday, May 17th, 2010Source: MedWire News
Atorvastatin therapy in patients with acute myocardial infarction (AMI) is associated with a dose-dependent improvement in coronary flow reserve (CFR), study findings indicate.
The research, by a Korean team, showed that this effect was driven by mobilization of circulating angiogenic cells together with a suppression of inflammatory cytokines and low-density lipoprotein (LDL) cholesterol.
The study, [...]
CENTAURUS suggests early apoB/apoA-1 ratio effect with rosuvastatin
Wednesday, April 14th, 2010Source: MedWire News
Treatment for 1 month with rosuvastatin 20 mg decreases the ratio of apolipoprotein (apo)B to A-1 more than does of atorvastatin 80 mg in patients with non-ST-elevation acute coronary syndromes (NSTE-ACS), trial findings suggest.
Both statins reduced apoB/apoA-1 ratio to a similar extent at the primary endpoint of 3 months in the Comparison of [...]
Addition of omega-3 fatty acids to atorvastatin improves lipid levels
Friday, February 5th, 2010Source: MedWire News
Taking prescription omega-3-acid ethyl esters (P-OM3) plus atorvastatin improves lipid levels to a significantly greater extent than atorvastatin plus placebo, report researchers.
“Unfortunately, a substantial proportion of patients with elevated non-high-density lipoprotein (HDL) cholesterol and triglyceride levels do not achieve non–HDL cholesterol level goals despite the use of statins,” say Harold Bays (Louisville Metabolic [...]
Research suggests high dose of atorvastatin prior to PCI may benefit chronic statin users.
Friday, July 3rd, 2009MedPage Today (7/1, Neale) reported that “patients on chronic statin therapy who re-loaded with high-dose atorvastatin (Lipitor) before percutaneous coronary intervention showed improved clinical outcomes in a randomized trial,” the findings of which were published online in the Journal of the American College of Cardiology. Since “most patients who show up in the cath lab [...]
More patients across the world lowering ‘bad’ cholesterol
Tuesday, June 23rd, 2009The percentage of patients lowering their elevated “bad” cholesterol to within target levels nearly doubled in the last decade, according to a multi-national survey reported in Circulation: Journal of the American Heart Association.
In the Lipid Treatment Assessment Project (L-TAP) 2 — a survey of nearly 10,000 patients (average age 62) from nine countries undergoing cholesterol-lowering [...]
Seniors warned about mixing OTC and prescription drugs
Monday, December 29th, 2008Seniors warned about mixing OTC and prescription drugs
According to researchers in the United States about 2.2 million seniors put themselves at high risk for drug interactions - they say many non-prescription medication, which are bought over-the-counter (OTC) can produce a harmful drug interactions.
The researchers from the University of Chicago Medical Center say more attention is [...]
