Cholesterol
« Previous EntriesTriglycerides best lipid risk marker for ischemic stroke
Thursday, February 24th, 2011Source: MedWire News
Nonfasting triglyceride levels are strongly associated with risk for ischemic stroke, whereas total cholesterol levels are not, shows an analysis of the Copenhagen City Heart Study.
Marianne Benn (Copenhagen University Hospital, Denmark) and colleagues say this is most likely because high triglyceride levels reflect elevated lipoprotein remnant cholesterol, and thus a particularly atherogenic lipid [...]
Combination therapy effective for treating mixed dyslipidemia in women
Wednesday, February 2nd, 2011Source: MedWire News
Study findings suggest that a combination of fibrate and statin therapies should be considered as a treatment option for women with mixed dyslipidemia.
Anne Goldberg (Washington University School of Medicine, St Louis, Missouri, USA) and colleagues show that combination therapy with fenofibric acid plus a statin is significantly more effective for increasing levels of [...]
More ‘aggressive’ treatment needed to achieve optimal lipid targets
Monday, January 31st, 2011Source: MedWire News
Most patients with coronary artery disease (CAD) are achieving the minimal recommended low-density lipoprotein (LDL) cholesterol goal, but many still have elevated levels of triglycerides or low levels of high-density lipoprotein (HDL) cholesterol despite treatment, say researchers.
In addition, few high-risk patients are achieving more aggressive LDL cholesterol goals recommended by the National Cholesterol [...]
Lifestyle changes in youth may prevent dyslipidemia later in life
Thursday, January 6th, 2011Lifestyle changes between youth and adulthood may have an effect on blood lipid and lipoprotein levels later in life, results from an Australian study suggest.
“Beneficial changes in modifiable risk factors (smoking and adiposity) in the time between youth and adulthood have the potential to shift those with high-risk blood lipid and lipoprotein levels in youth [...]
Fenofibrate therapy reduces burden of oxidative stress
Thursday, December 30th, 2010Source: MedWire News
Treatment with fenofibrate leads to a reduction in biomarkers of oxidative stress, US researchers have shown.
Given the established role of oxidative stress in atherogenesis, the team hypothesizes that these observations “may partially explain the efficacy of fenofibrate in reducing cardiovascular events.”
Researchers led by Michael Tsai (University of Minnesota, Minneapolis, USA) measured levels of [...]
Alzheimer’s disease risk decreased by high levels of HDL cholesterol
Tuesday, December 14th, 2010Source: MedWire News
High levels of high-density lipoprotein (HDL) cholesterol may be associated with a decreased risk for Alzheimer’s disease in elderly individuals, research shows.
The team reports that high HDL cholesterol levels were associated with a 40% decreased risk for both probable and possible Alzheimer’s disease.
“In addition, higher levels of total cholesterol, non-HDL cholesterol, and low-density [...]
Need for ‘more intensive treatment’ of dyslipidemia in Canadian patients
Tuesday, November 23rd, 2010Source: MedWire News
Findings from the DYSlipidemia International Study (DYIS) suggest that treatment for dyslipidemia should be intensified in Canadian patients, especially among those who are at high risk.
Only 63% of all patients in the study met the low-density lipoprotein (LDL) cholesterol guideline levels, including just 55% of high-risk patients.
“The findings suggest the possibility that, in [...]
LDL cholesterol treatment ‘not satisfactory’
Monday, November 1st, 2010Source: MedWire News
Lipid-lowering treatment for patients at high risk for coronary heart disease (CHD) has improved, but is still not satisfactory, German researchers say.
In the journal Clinical Research in Cardiology, they report that only 43.8% of high-risk patients achieved the target low-density lipoprotein (LDL) cholesterol level of <100 mg/dl, as defined by the National Cholesterol Education [...]
Blood glucose promotes lipoprotein(a) oxidization
Wednesday, September 29th, 2010Source: MedWire News
Blood glucose levels influence the oxidization of lipoprotein(a), a molecule with potent atherosclerotic properties, research has found.
The study was undertaken by Kazuhiko Kotani (Jichi Medical University, Tochigi, Japan) and co-workers and aimed to investigate the association between circulating levels of oxidized Lp(a) [oxLp(a)] and cardiometabolic variables.
The study participants were 70 healthy women with [...]
Fenofibrate, niacin ‘largely comparable’ in atherogenic dyslipidemia
Tuesday, September 14th, 2010Source: MedWire News
Fenofibrate and niacin are “largely comparable” as treatments for patients with hypertriglyceridemia and low levels of high-density lipoprotein (HDL) cholesterol, a randomized trial has found.
However, the two treatments had different effects on glucose metabolism and inflammation, leading the authors to recommend an individualized approach to the pharmacologic treatment of atherogenic dyslipidemia.
A team led [...]
