Plavix
« Previous EntriesHigh Doses Of Plavix May Be Good For Some Patients, But Not All.
Tuesday, September 14th, 2010Source: DIA Daily
HealthDay (9/1, Reinberg) reported that “more isn’t necessarily better when prescribing the two drugs commonly used to treat patients who are in danger of having a heart attack, Plavix (clopidogrel) and aspirin,” according to a study. Two separate “reports on the data,” one published online in The Lancet and the [...]
Reduced Plavix Efficacy Associated With Specific Gene Variants Confirmed In Two New Analyses, But Not In A Third.
Monday, August 30th, 2010Source: DIA Daily
The Wall Street Journal (8/30, Winslow) reports that for patients with acute coronary syndrome, physicians often turn to Sanofi-Aventis and Bristol-Myers Squibb’s Plavix (clopidogrel) to prevent clot-induced strokes and heart attacks. However, a significant number of patients carry genetic variations that impede the drug’s effectiveness. While some believe [...]
Early dual antiplatelet therapy cuts microemboli risk after cerebral stenosis
Wednesday, May 5th, 2010Source: MedWire News
Early combination antiplatelet therapy results in fewer microemboli relative to aspirin monotherapy in patients with symptomatic cerebral or carotid artery stenosis, show results of the CLAIR study.
“Clinical trials are now warranted to investigate whether this combination treatment also results in a reduction in stroke incidence,” write the CLAIR (Clopidogrel plus aspirin versus aspirin [...]
Plavix May Reduce Death Risk In Patients With Certain Heart Conditions.
Tuesday, March 23rd, 2010HealthDay (3/22, Preidt) reported that “Plavix [clopidogrel] is of modest benefit in cutting the odds of death in patients with heart failure and heart attack who don’t undergo angioplasty,” according to a study published in the Journal of the American College of Cardiology. In the study, “there were 812 deaths (32.2 [...]
New anti-clotting drug performs better than Plavix in study.
Thursday, January 14th, 2010Source: DIA Daily
MedPage Today (1/13, Peck) reported that, “among patients who underwent planned stenting for treatment of acute coronary syndromes, those treated with the investigational antiplatelet agent ticagrelor (Brilinta) had fewer cardiovascular events than patients who received clopidogrel (Plavix).” This “finding emerged from a prespecified subset analysis of the PLATO [...]
PPIs and Plavix — Confusion Reigns Supreme
Wednesday, November 18th, 2009By Burt Cohen
Patients taking Plavix (a.k.a. clopidogrel) — and that would be all stent patients — sometimes experience a side effect of gastric upset, heartburn or even bleeding. So they are given a Proton Pump Inhibitor (PPI) with a brand name of Prilosec, Nexium, Prevacid or Protonix to alleviate these symptoms.
In the past a number of [...]
Double dose of Plavix better for certain angioplasty patients
Tuesday, September 29th, 2009HealthDay (9/28, Edelson) reported that “cardiologists are looking at the next generation of clot-busters that could replace Plavix [clopidogrel].” In a study “published in the Oct. 6 issue of the Journal of the American College of Cardiology,” researchers “found that a 600-milligram dose of Plavix is more effective than a 300-milligram [...]
Heart Patients Safely Combine Plavix, Heartburn Pills
Monday, August 31st, 2009Heart patients can safely take drugs to prevent blood clots from forming with pills to protect the stomach against heartburn and ulcers, a study found.
The results should ease concerns that mixing the medications may reduce the effectiveness of Bristol-Myers Squibb Co. and Sanofi-Aventis SA’s Plavix blood thinner, used daily by millions of people to [...]
Research suggests adding Plavix to aspirin may reduce heart risks in atrial fibrillation patients.
Wednesday, April 1st, 2009The Wall Street Journal (4/1, D5, Loftus) reports that “adding the anticlotting drug Plavix [clopidogrel] to aspirin in people with” atrial fibrillation “modestly reduced the combined risk of strokes and related disease versus aspirin alone,” according to a study presented at the American College of Cardiology conference and published online in the New England Journal [...]
US FDA seeks more data on bloodthinner PlavixUS FDA seeks more data on bloodthinner Plavix
Tuesday, January 27th, 2009US FDA seeks more data on bloodthinner Plavix
U.S. health regulators are reviewing the effectiveness in some patients of the widely used blood thinner Plavix, made by Sanofi-Aventis SA and Bristol-Myers Squibb Co.
The move comes after several studies found the blockbuster drug did not work as well in certain people possibly because patients metabolized it differently depending [...]
