Tamoxifen

Longer treatment with Tamoxifen reduces risks of cancer recurrence

Friday, March 25th, 2011

New research has found that a 5-year course of the breast cancer drug Tamoxifen works better than a 2-year course of the drug. The study, the results of which were published online in the Journal of Clinical Oncology, was conducted by scientists at the Cancer Research UK. The results have once again pointed out the [...]

Discovery could enhance tamoxifen’s effectiveness

Friday, October 22nd, 2010

Source: MedWire News
UK researchers have identified a potential therapeutic target to enhance the sensitivity of estrogen receptor α (ERα)-positive breast cancers to endocrine therapy with drugs such as tamoxifen.
Targeting the protein RET (REarranged during Transfection) could also resensitize tamoxifen-resistant tumors to treatment with tamoxifen, report Clare Isacke (Institute of Cancer Research, London) and colleagues in [...]

Cognitive Function Is Superior In Breast Cancer Patients Treated With Letrozole Versus Tamoxifen

Friday, July 17th, 2009

Source: Medical News Today
New results show that postmenopausal women with breast cancer receiving adjuvant letrozole have better cognitive function than women being treated with tamoxifen. The data, from a recent meeting of the American Society of Clinical Oncology (ASCO), are drawn from a sub-study of the Breast International Group (BIG) 1-98 trial.
The trial, which enrolled [...]

Study finds many breast-cancer patients stop taking tamoxifen as prescribed.

Wednesday, December 17th, 2008

“Many breast cancer patients are risking their lives by failing to take the tamoxifen they are prescribed,” according to a study published in the British Journal of Cancer. Lead author Professor Alastair Thompson, of the University of Dundee, and colleagues, conducted an “analysis of more than 2,000 women’s prescription records.” The researchers found that “50 [...]