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Artificial Sweeteners Linked to Weight Gain

By jeremyc | November 24, 2016

Several beverages, including diet soda, and prepared foods use Aspartame in place of sugar. Those trying hard to shed extra pounds commonly use Aspartame, for it reduces the total calorie intake. But new research reveals that this artificial sweetener might not help you lose weight. More disturbingly, the study hints it might have the contrary effect.

Some earlier studies had hinted that taking aspartame in acceptable amount, as directed by the FDA, might cause you to eat more and consequently gain weight.

On the other hand, some animal studies have revealed that artificial sweeteners, such as aspartame and saccharin, trigger weight gain, not weight loss.

While earlier studies debunked the claim that artificial sweeteners help weight loss, they couldn’t explain why they this was so. The researchers of this study took upon themselves to unearth the secret behind inefficacy of artificial sweeteners to promote weight loss.

The researchers found that the answer lay in one of metabolites of aspartame, called phenylalanine, which blocks the activity of intestinal alkaline phosphatase (or IAP for short).

IAP prevents symptoms that are linked to obesity, heart disease, and type 2 diabetes in rodents. So when aspartame is consumed, symptoms related to the aforesaid conditions become more prominent because of inhibition of IAP, and this in turn prevent weight loss and might lead to weight gain.

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