Artemether/Lumefantrine 80/480mgGeneric Alternative to Coartem
What is a generic medication?
Generic medications are significantly discounted copies of brand name medication that have the same active ingredients, intended use, dosage, side effects, effects, and route of administration as the original brand name medication. In other words, generic medications have the same pharmacological effects as their brand-name counterparts. Over half of all prescribed medications are for generic medications.
Artemether/Lumefantrine Drug Information
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You can easily place an order on our website in under 5 minutes. First you need to set up an account with us, create a payment method, and send us your prescriptions. Alternatively, you can order by downloading our order form or by placing an order over the phone. Delivery can take approximately 2 weeks to North America, and 4 weeks to other countries.
Artemether/Lumefantrine 80/480mg is used to treat malaria in adults and children. The two ingredients in Artemether/Lumefantrine 80/480mg belong to a class of drugs known as antimalarials. Malaria is an infection caused by mosquito bites received while traveling or living in regions of the world where malaria is common. Malaria parasites enter the body, and live in body tissues such as red blood cells or the liver. Artemether/Lumefantrine 80/480mg is used to kill the malaria parasites living inside red blood cells. In some cases, you may need to take a different medication (such as primaquine) to kill the malaria parasites living in the liver. Both treatments may be needed for a complete cure and to avoid the return of infection (relapse). Artemether/Lumefantrine 80/480mg is not used to prevent malaria. The United States Centers for Disease Control provide updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Discuss the most recent information with your doctor before starting treatment with Artemether/Lumefantrine 80/480mg.
How to Use Artemether/Lumefantrine
Read the Patient Information Leaflet if available from your pharmacist before you start taking Artemether/Lumefantrine 80/480mg and each time you get a refill. If you have any questions regarding the information, ask your doctor or pharmacist. Take Artemether/Lumefantrine 80/480mg by mouth, with food, exactly as prescribed by your doctor. Artemether/Lumefantrine 80/480mg is usually taken twice a day with a meal for 3 days (6 doses) or as directed by your doctor. On your first day of treatment, take your first dose with food, followed by your second dose 8 hours later. Then each day for the next 2 days, take one dose in the morning and one dose in the evening. It is important to take every dose of Artemether/Lumefantrine 80/480mg with food or milk, infant formula, pudding, porridge, or broth. Food helps Artemether/Lumefantrine 80/480mg work better. Tell your doctor if you are unable to eat. If you or your child cannot swallow tablets, the artemether/lumefantrine tablets may be crushed and mixed with one or two teaspoons (5 to 10 milliliters) of water in a clean container at the time your dose is due. Do not crush tablets or mix with water in advance. Follow the dose of medication with food or drink (such as whole milk, formula, pudding, broth, or porridge). If you or your child vomits within 1 to 2 hours of taking Artemether/Lumefantrine 80/480mg, repeat this dose and contact your doctor right away. You will need to make sure you have enough tablets to complete your full course of therapy. If you vomit 2 doses, you may need to be treated with a different medication. The Dosage of Artemether/Lumefantrine 80/480mg is based on your medical condition, weight, and response to treatment. It is very important to continue taking Artemether/Lumefantrine 80/480mg exactly as prescribed by your doctor. Do not take more or less of Artemether/Lumefantrine 80/480mg than prescribed. Do not skip any doses. Continue to take Artemether/Lumefantrine 80/480mg until the full prescribed amount is finished, even if symptoms disappear after a few doses. Skipping doses or stopping the medication too early may make the infection more difficult to treat and result in a return of the infection. Artemether/Lumefantrine 80/480mg works best when the amount of drug in your body is kept at a constant level. Therefore, take Artemether/Lumefantrine 80/480mg at evenly spaced intervals. To help you remember, take it at the same times each day. Avoid eating grapefruit or drinking grapefruit juice while using Artemether/Lumefantrine 80/480mg unless your doctor instructs you otherwise. Grapefruit can increase the amount of Artemether/Lumefantrine 80/480mg in your bloodstream. Consult your doctor or pharmacist for more details. Seek immediate medical attention if your symptoms of malaria (such as fever, chills, headache, other flu-like symptoms), persist or worsen after 1 to 2 days of taking Artemether/Lumefantrine 80/480mg. If your fever returns after completing this prescription, contact your doctor so that he/she can determine whether the malaria has returned. Quick treatment of malaria is needed to prevent serious, possibly fatal, outcomes.
Before taking artemether/lumefantrine, tell your doctor or pharmacist if you are allergic to artemether or lumefantrine; or if you have any other allergies. Artemether/Lumefantrine 80/480mg may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using Artemether/Lumefantrine 80/480mg, tell your doctor or pharmacist your medical history,recent use (within the past month) of any medication to prevent or treat malaria (such as halofantrine, quinine, or quinidine), kidney problems, liver problems. Artemether/lumefantrine may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away. The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation. Before using artemether/lumefantrine,certain heart problems (heart failure, slow heartbeat, QT prolongation in the EKG), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death). Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your doctor about using artemether/lumefantrine safely. Artemether/Lumefantrine 80/480mg may make you feel dizzy or tired or weak. Alcohol or marijuana (cannabis) can make you more dizzy or tired. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis). Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Older adults may be more sensitive to the side effects of Artemether/Lumefantrine 80/480mg, especially QT prolongation (see above). During pregnancy, Artemether/Lumefantrine 80/480mg should be used only when clearly needed. Discuss the risks and benefits with your doctor. It is unknown if Artemether/Lumefantrine 80/480mg passes into breast milk. Consult your doctor before breast-feeding.
If you miss a dose of Artemether/Lumefantrine 80/480mg, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.
See also How to Use section. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Be sure to tell your doctor about all medications you take for malaria within the 4 weeks before, during, and after treatment with artemether/lumefantrine. Some antimalarial drugs (such as halofantrine) should not be used within one month of treatment with artemether/lumefantrine. In some cases a serious (possibly fatal) drug interaction may occur. Many drugs besides artemether/lumefantrine may affect the heart rhythm (QT prolongation), including other antimalarial drugs (such as quinine, quinidine), antiarrhythmic drugs (such as amiodarone, sotalol, procainamide, disopyramide), antipsychotics (such as pimozide, ziprasidone), macrolide antibiotics (such as erythromycin), quinolone antibiotics (such as ciprofloxacin, moxifloxacin), among others. Other medications can affect the removal of artemether/lumefantrine from your body, which may affect how Artemether/Lumefantrine 80/480mg works. Examples include some anti-seizure drugs (such as carbamazepine, phenobarbital, phenytoin), azole antifungals (such as ketoconazole, itraconazole), mefloquine, HIV NNRTIs (such as delavirdine, efavirenz), HIV protease inhibitors (such as nelfinavir, ritonavir), rifamycins (such as rifabutin, rifampin), St. John's wort, among others. Artemether/Lumefantrine 80/480mg can speed up or slow down the removal of other medications from your body, which may affect how they work. Examples of affected drugs include clomipramine, flecainide, certain beta blockers such as metoprolol, certain tricyclic antidepressants (such as amitriptyline and imipramine), among others. Artemether/Lumefantrine 80/480mg may decrease the effectiveness of hormonal birth control such as pills, patch, or ring. This could cause pregnancy. Discuss with your doctor or pharmacist if you should use additional reliable birth control methods while using Artemether/Lumefantrine 80/480mg. Also tell your doctor if you have any new spotting or breakthrough bleeding, because these may be signs that your birth control is not working well.
Artemether/Lumefantrine Side Effects
What are Artemether/Lumefantrine side effects?
Side effects are physical, mental or emotional symptoms which occur in addition to or outside of the desired effect of a therapeutic treatment such as an over-the-counter or prescribed drug or medication. Side effects from Artemether/Lumefantrine may occur at the beginning or at the end of treatment and may also depend on the length of time an individual remains on the treatment. Side effects, also known as adverse effects, are generally more likely to occur when starting treatment. Individuals may also experience side effects from Artemether/Lumefantrine as a result of an interaction with other medications.
Side Effects of Artemether/Lumefantrine
The side effects of Artemether/Lumefantrine may vary in number and intensity for many different reasons. Factors such as age, weight, gender and ethnicity may influence the side effects of Artemether/Lumefantrine. Also, an individual’s state of general physical health and seriousness of the disease or illness as well as an increase or decrease in dosage may lead to side effects. Further, side effects from Artemether/Lumefantrine may also occur as a result of an interaction with certain herbal supplements, foods or drinks.
Prescription drug side effects can be serious and may cause patients to stop the treatment. However, when side effects from the use of a prescription drug, such as Artemether/Lumefantrine, do occur a patient should consult their physician. A physician may prescribe an additional treatment in order to control the symptoms or an adjustment in the dosage may be made. In addition, changes to diet, exercise or other lifestyle activities may help to lessen the side effects of Artemether/Lumefantrine.
By understanding side effects and the factors which may influence the occurrence of side effects patients are empowered to take an active role in their care. Patients who have specific questions about the side effects of Artemether/Lumefantrine, or any other medication, should contact their physician. General information about Artemether/Lumefantrine and the side effects associated with Artemether/Lumefantrine are described in the following:
Common Artemether/Lumefantrine Side Effects
- headache disorder
- general weakness
- sleep disorder
Less Frequent Artemether/Lumefantrine Side Effects
- acute abdominal pain
- pruritus of skin
- skin rash
- back pain
Rare or Very Rare Artemether/Lumefantrine Side Effects
- prolonged QT interval
- peptic ulcer
- abnormal hepatic function tests
- thrombocytopenic disorder
- bullous dermatitis
- hypersensitivity drug reaction
- acquired hemolytic anemia
Store at room temperature away from light and moisture. Do not store in bathroom. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard Artemether/Lumefantrine 80/480mg when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
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