Ibuprofen Side Effects

What are Ibuprofen side effects?

Side effects are physical, mental or emotional symptoms which occur in addition to or outside of the desired effect of a therapeutic treatment such as an over-the-counter or prescribed drug or medication. Side effects from Ibuprofen may occur at the beginning or at the end of treatment and may also depend on the length of time an individual remains on the treatment. Side effects, also known as adverse effects, are generally more likely to occur when starting treatment. Individuals may also experience side effects from Ibuprofen as a result of an interaction with other medications.

Side Effects of Ibuprofen

The side effects of Ibuprofen may vary in number and intensity for many different reasons. Factors such as age, weight, gender and ethnicity may influence the side effects of Ibuprofen. Also, an individual’s state of general physical health and seriousness of the disease or illness as well as an increase or decrease in dosage may lead to side effects. Further, side effects from Ibuprofen may also occur as a result of an interaction with certain herbal supplements, foods or drinks.

Prescription drug side effects can be serious and may cause patients to stop the treatment. However, when side effects from the use of a prescription drug, such as Ibuprofen, do occur a patient should consult their physician. A physician may prescribe an additional treatment in order to control the symptoms or an adjustment in the dosage may be made. In addition, changes to diet, exercise or other lifestyle activities may help to lessen the side effects of Ibuprofen.

By understanding side effects and the factors which may influence the occurrence of side effects patients are empowered to take an active role in their care. Patients who have specific questions about the side effects of Ibuprofen, or any other medication, should contact their physician. General information about Ibuprofen and the side effects associated with Ibuprofen are described in the following:

Common Ibuprofen Side Effects


  • skin rash

Less Severe

  • dizziness
  • nausea
  • heartburn

Less Frequent Ibuprofen Side Effects


  • body fluid retention
  • tinnitus
  • pruritus of skin
  • edema

Less Severe

  • gastric acid hypersecretory conditions
  • constipation
  • anorexia
  • headache disorder
  • vomiting
  • flatulence
  • diarrhea
  • Acute Abdominal Pain
  • Nervousness
  • Irritability
  • dyspepsia

Rare or Very Rare Ibuprofen Side Effects


  • non-infective meningitis
  • hemolytic anemia
  • pancytopenia
  • aplastic anemia
  • anemia
  • thrombocytopenic disorder
  • agranulocytosis
  • leukopenia
  • neutropenic disorder
  • eosinophilia
  • acute confusion
  • mood changes
  • depression
  • peripheral neuropathy
  • diplopia
  • scotomata
  • blurred vision
  • visual changes
  • conjunctivitis
  • dry eye
  • toxic amblyopia
  • hypertension
  • acute myocardial infarction
  • cardiac arrhythmia
  • chronic heart failure
  • cerebrovascular accident
  • vasculitis
  • Rhinitis
  • Laryngeal Edema
  • bronchospastic pulmonary disease
  • aphthous stomatitis
  • esophageal ulcer
  • gastric ulcer
  • peptic ulcer
  • gastrointestinal perforation
  • gastrointestinal ulcer
  • gastritis
  • hepatitis
  • drug-induced hepatitis
  • acute pancreatitis
  • bloody stools
  • gastrointestinal hemorrhage
  • nephrotoxicity
  • renal tubular necrosis
  • renal failure
  • renal papillary necrosis
  • kidney disease with reduction in GFR
  • cystitis
  • hematuria
  • abnormal vaginal bleeding
  • allergic dermatitis
  • bullous dermatitis
  • Erythema Multiforme
  • toxic epidermal necrolysis
  • Stevens-Johnson Syndrome
  • exfoliative dermatitis
  • urticaria
  • lupus-like syndrome
  • altered mental status
  • hallucinations
  • Jaundice
  • epistaxis
  • wheezing
  • dyspnea
  • chest tightness
  • bloody vomit
  • polyuria
  • abnormal hepatic function tests
  • Anaphylaxis
  • angioedema
  • serum sickness
  • chest pain
  • Worsening of Chronic Heart Failure
  • hyperkalemia

Less Severe

  • hearing loss
  • xerostomia
  • mouth irritation
  • skin photosensitivity
  • drowsy
  • insomnia
  • flushing
  • tachycardia
  • palpitations
  • ecchymosis
  • symptoms of anxiety