Progesterone Might Help Reduce Preterm Birth Risk

By jeremyc | November 20, 2017

A recent study provides further support for using vaginal progesterone for lowering the risk of neonatal complications and preterm birth, as well as of infant death in those pregnant women who have a short cervix. According to experts, a short cervix predicts preterm birth more accurately than any other predictor.

These are substantial findings and medical experts are excited about it. This is because preterm birth causes more number of deaths among children who are less than 5 years old than any other condition.

In the U.S., preterm birth rate has increased for two consecutive years, 2015 and 2016. Before that, for several years preterm birth rate had declined.

When a baby is born before 37th week of pregnancy, it is called preterm birth. The cervix becomes thin and shorter during pregnancy. This is a natural phenomenon as a woman’s body prepares itself for birth. However, in case of some women, cervix thins and becomes shorter earlier than usual.

Previous research found that inserting progesterone into vagina as a tablet or gel was linked to a lower preterm birth risk linked to short cervix.

The researchers analyzed data of 974 women to confirm the effectiveness of progesterone. All of these women had a shortened cervix, but only some were given vaginal progesterone. In comparison to women who had received no treatment or a placebo, women who were given vaginal progesterone recorded considerable reduction in preterm birth risk.

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Research Suggest Resolvin E1 Might Help Prevent and Treat Atherosclerosis

By jeremyc | November 19, 2017

Previous research has shown that when Resolvin E1 is applied topically on gum tissue then it helps prevent as well as treat gum disease. New research shows that Resolvin E1 benefits might extend further. The researchers have noted that Resolvin E1 reduces the chances of rupturing of advanced arterial atherosclerotic plaques and forming dangerous blood clots. Our body produces this molecule naturally from omega-3 fish oil.

According to experts, this is a significant result and can pave the way for effective treatments without serious side effects in individuals who have cardiovascular disease with or without gum disease.

Latest evidence, gathered from several research groups, suggests chronic inflammatory conditions, including heart disease, diabetes, kidney disease, rheumatoid arthritis, pulmonary diseases, colitis, Alzheimer’s disease, and cancer can gain from use of lipoxins and resolvins, both of which are pro-resolving lipid mediators.

To check how effective lipid mediators actually are in case of advanced atherosclerosis treated one group of experimental model of advanced atherosclerosis with a solution containing Resolvin E1. This solution was topically applied on gum. On the other hand, salt water was used to treat the second group.

Minimal atherosclerosis was observed in Resolvin E1 group. Rupturing of plaque in aortic artery was also reduced in this group. In comparison, atherosclerosis became more severe in the group treated with salt water.

 

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Vitamin D Levels Might Affect Success Rate of Fertility Treatment

By jeremyc | November 18, 2017

According to a recent meta-analysis, women with adequate vitamin D levels have a better success rate with their fertility treatment.

A distressing issue, infertility is now quite common and is estimated to affect no fewer than 6.1 American couples. More and more couples are now seeking fertility treatment, including fertility medication and IVF. The success rates of fertility treatment now are better than before.

IVF success rates in America are between 13 to 43 percent. Initially the success rates of fertility treatment improved because of better methods of selecting out those embryos which had the maximum chances of survival. However, recently, the success rates of fertility treatment have become more or less stagnant.

That’s why researchers are focusing on potential factors that can help improve this. One potential factor that’s come under focus is vitamin D.

In a few animal studies, the researchers noted that deficiency of vitamin D was linked to poorer fertility. In humans, deficiency of vitamin D has been linked to increased risk preeclampsia, gestational diabetes, low birthweight, and gestational hypertension.

Spurred on by these observations, the researchers decided to perform a meta-analysis of 11 studies. These studies were done on women undergoing fertility treatment.

The researchers noted the chance of giving a live birth was 33 percent greater in women who had adequate levels of vitamin D, compared to women with vitamin D deficiency.

 

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FDA Approves Sutent for Lowering Risk of Kidney Cancer Recurring

By jeremyc | November 17, 2017

The FDA has given approval for Sutent to be used for adjuvant treatment of adult patients in whom the risk of kidney cancer recurring is high after surgical removal of a kidney. Adjuvant treatment is defined as a therapy which is started after a patient has had a surgical removal to reduce the chances of cancer returning.

This drug comes in the category of kinase inhibitors and works by inhibiting several enzymes which play a key role in cell growth. In 2006, Sutent was initially approved for treating certain patients having gastrointestinal stromal tumors and advanced renal cell carcinoma. This drug was also given approval for patients having certain kind of cancer of the pancreas. With this approval, Sutent use has been expanded.

Incidentally, Sutent is the first drug to be approved as adjuvant treatment for renal cell carcinoma patients. According to experts, this is a significant development because renal cell carcinoma patients who have had a surgical removal of a kidney are usually at greater risk of cancer returning.

Like other drugs, Sutent might cause side effects. Common side effects of this drug include diarrhea, fatigue, nausea, mucositis, reduced appetite, abdominal pain, vomiting, hypertension, altered taste, bleeding events, and indigestion.

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Owning a Dog Linked with Lower All Cause Mortality

By jeremyc | November 16, 2017

There’s some great news for people who own dogs. Owning a dog might significantly lower the risk of premature death, according to a new study.

Many people love dogs—and that’s good for them. In this study, the researchers analyzed data of over 3.4 million people and noticed that individuals who kept a dog had a reduced risk of all-cause mortality and cardiovascular death over a period of 12 years, compared to those who don’t have a dog.

Many studies in recent times have stated that dogs are beneficial for our overall health. While one recent study linked dogs with reduced childhood stress, another said that people who let their dog sleep in their room experience better sleep quality.

For this study, researchers studied data of 3,432,153 adults, none of whom had cardiovascular disease at the start of the study. The average follow-up period was 12 years.

The researchers noted that the risk of all-cause mortality in multi-person households who owned a dog was 11 percent lower than multi-person households without a dog. The benefit was even greater in case of one-person households with a dog. Their risk of all-cause mortality was 33 percent lower.

In addition, the risk of cardiovascular death was 36 percent lower in one-person households who owned a dog and 15 percent lower in multi-person households with a dog.

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Diabetes Risk Increases with Increase in Psoriasis Severity

By jeremyc | November 15, 2017

Psoriasis is linked with type 2 diabetes. However, for the first time a study has shown that the risk of diabetes increases with the severity of psoriasis.

A severe medical condition, psoriasis is believed to affect approximately 7.5 million individuals in America. The condition develops because of immune system transmits faulty signals, disrupting normal biology of joints and skin.

People who have psoriasis are more likely to develop other medical conditions, such as diabetes, a condition which develops when the body is unable to properly use insulin, a hormone produced by beta cells in the pancreas to convert sugar into energy. It is estimated that diabetes type 2 accounts for nearly 90-95 percent of all diabetes cases.

For this study, the researchers studied data of two groups of participants. One group included 8,124 adults, all of whom had psoriasis. The other group had 76,599 people with diabetes.

The researchers noted that risk of developing diabetes was 21 percent more in psoriasis patients with BSA of 2 or lower, compared to those without psoriasis. BSA is used for measuring the severity of psoriasis.

When BSA was 10 percent or more, the risk of diabetes type 2 was found to be 64 percent more than people who didn’t have psoriasis. Additionally, the risk of diabetes increases by 20 percent for every 10 percent increase above 10 percent BSA, compared to non-psoriasis individuals.

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Coffee is good for liver health

By jeremyc | November 14, 2017

Do you enjoy your daily cup of joe, like million others in the world? If yes, there’s some good news for you and all coffee lovers. A latest report has linked coffee drinking with lower risk of liver disease. According to this report, coffee intake might lower liver disease risk by 70 percent.

All over the world, people love coffee. Now this report suggests our livers too like coffee.

Chronic liver disease causes thousands of death every year in the U.S. What’s worse is that the incidence of chronic liver disease in western world is on the rise. Contributing factors to this disturbing trend include excess alcohol, fat, and calorie intake.

The latest report shows an easy way to protect liver health. The finding reveals that compared to those who don’t drink coffee, people who drink coffee are 40 percent less likely to develop liver cancer.

Many health experts believe that some existing liver problem leads to development of liver cancer. Therefore, reduced liver cancer risk linked with coffee drinking is likely to be because of protective effect of coffee on liver.

Some studies have also linked coffee drinking to better liver health. They have hinted at 25-70 percent lower risk of developing liver cirrhosis. Some studies investigated the effect of coffee on non-alcoholic fatty liver disease. The results were encouraging. Coffee drinking was linked with reduced risk of non-alcoholic fatty liver disease.

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Diet Rich in Leafy Greens & Whole Grain Foods Linked to Reduced Risk of Heart Failure

By jeremyc | November 13, 2017

People who predominately follow plant-based diet—a lot of vegetables, especially leafy greens, and whole grain foods—have a lower risk of developing heart failure.

When heart failure occurs, the heart is not able to pump blood adequately around the body. It is estimated that in 5.7 American adults are living with heart failure, a condition which is usually incurable and can be managed on long-term basis only through appropriate treatment. For this reason only, scientists are constantly trying to identify risk factors of heart failure and methods to avoid them.

Previous research has suggested that diet affects risk of developing atherosclerosis, a condition in which arteries become narrow because of plaque buildup. Atherosclerosis is a big risk factor for heart failure, heart attack, and stroke.

Encouraged by these findings, the researchers set out to check if there’s a link between diet and heart failure risk, and monitored data of more than 15,000 individuals. All of these individuals had participated in another study and didn’t have heart failure or coronary heart disease at the start of that study. The participants were divided into different groups based on their dietary habits.

The researchers noted that people who followed plant-based diet had the lowest risk of heart failure.

 

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Regular Exercise Might Reduces Glaucoma Risk

By jeremyc | November 12, 2017

According to new research, moderate intensity exercise, like jogging or brisk walking, might reduce the risk of developing glaucoma.

In glaucoma, the optic nerve of the eye gets damaged, leading to vision loss. There are many different types of glaucoma, the most common being open-angle glaucoma. This condition is marked by increased eye pressure.

Glaucoma is the number one cause of non-reversible blindness. At present, glaucoma is incurable. However, the good news is that if the condition is diagnosed early, treatments are available which reduce the progression rate of the disease and helps preserve vision.

Glaucoma is quite a common condition. It is estimated that no fewer than 3 million individuals in America have glaucoma.

People with diabetes are at an increased risk of developing glaucoma. When glaucoma has set in, certain lifestyle factors can help minimize vision loss. These are maintaining healthy weight, exercising regularly, and keeping blood pressure under control. All of these factors also reduce risk of diabetes, which, as said previously, is linked to glaucoma.

Many health experts have long believed lifestyle choices have no bearing on glaucoma itself. However, a few latest studies have revealed that lifestyle factors affect eye pressure, which in turn is linked to glaucoma.

In this study, the researchers noted that people who are physically active are less likely to develop glaucoma than those who aren’t. In fact regular exercise can reduce glaucoma risk by as much as 73 percent.

 

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Excessive TV Viewing Increases Risk of Venous thromboembolism

By jeremyc | November 11, 2017

According to a new study, people who watch TV very often have a greater risk of developing venous thromboembolism, compared those who hardly watch TV.

Venous thromboembolism (or VTE for short) is used to refer different conditions involving blood clots in veins. The term includes pulmonary embolism (or PE for short) as well as deep vein thrombosis (or DVT for short).

When blood clots develop in veins like pelvis, arms, or legs, it is called DVT. On the other hand, when a blood clot enters the arteries of lungs, it is called PE.

VTE is the third most common vascular condition, the first two being heart attacks and strokes. This is the first study in which TV viewing was linked to greater risk of VTE.

In this study, the researchers study data of more than 15,000 people, all of whom were asked to categorize their TV viewing in any of the 4 categories: “very often,” “never or rarely,” “often,” and “sometimes”.

Compared to individuals in “never or rarely” category, people who reported watching TV  very often showed a 1.7 times greater risk of developing VTE.

What’s more, this risk was the same for individuals in the “very often” group reported who reported exercising regularly.

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