Use NSAIDs only for a valid indication, experts advise

By jeremyc | March 25, 2017

Non-steroidal anti-inflammatory drugs like ibuprofen are available without prescription and are commonly used for pain and other reasons. However, past research has shown NSAIDs to increase the risk of heart attack, stroke, heart failure, and arrhythmia. A latest study confirms ibuprofen to increase the risk of cardiac arrest.

Following this finding, the researchers are asking whether it would be much safer to impose restrictions on ibuprofen and other over-the-counter NSAIDs.

The present study was conducted by Danish researchers. For this study, the researchers analyzed records of 28,947 individuals who had experienced a cardiac arrest (defined as a sudden stopping of the heart’s functioning) outside hospital. It was found that over 3,000 of these people had used an NSAID in 30 days prior to cardiac arrest.

The researchers found that Diclofenac increased the risk of cardiac arrest by 50 percent. In the U.S., Diclofenac can be bought only with a prescription. Prescription-strength ibuprofen was found to increase the risk of cardiac arrest by 31 percent.

According to health experts, it is important that NSAIDs should only be used only for a sound indication. People diagnosed with cardiovascular disease shouldn’t use NSAIDs, nor should people with an increased risk of heart disease.

Topics: Cardiovascular | No Comments »

New studies show how broccoli helps against cancer

By jeremyc | March 24, 2017

Past studies have hinted at sulforaphane being an anti-cancer agent. It has been hailed as a natural compound that can help prevent cancer as well as slow the speed at which cancer spreads. A new study might have found how sulforaphane does it.

Sulforaphane is found in the highest amount in broccoli. Other cruciferous vegetables also contain it in high amounts.

In the present study, the researchers found that sulforaphane lowers the expression of lncRNAs and this in turn affected the ability of cancer cells to metastasize.

Scientists had earlier labeled lncRNAs as “junk DNA” because they thought it has no important function to play. However, recent research shows that lncRNAs play a significant role in development of many cancers, such as lung, stomach, prostate, and breast cancer.

Studies have hinted at IncRNAs possessing the ability to regulate gene expression. Scientists believe when IncRNAs is out of order, diseases get a favorable environment to develop.

In addition to showing the important role that lncRNAs play in cancer development, the recent study supports the claim of sulforaphane being useful in cancer prevention which previous studies had made.

According to the researchers, with sulforaphane’s anti-cancer properties coming to light once again, in future we could have new drugs, dietary strategies, and foods that can be used for cancer prevention or treatment.

 

Topics: Cancer | No Comments »

Six Unsaturated Fatty Acids Linked to Alzheimers, New Research Says

By jeremyc | March 23, 2017

The exact cause of Alzheimer’s is not known. However, to gain better insight into development of this neurodegenerative disorder, researchers are analyzing a range of causes, from genetic to lifestyle and environmental. In a recent research, scientists examined certain key parts of the brain known to be associated with Alzheimer’s and found six fatty acids are linked with it.

Alzheimer’s is the most common form of dementia accounting for up to 80 percent of all dementia cases. Data suggests that one in every three elderlies have Alzheimer’s.

For this study, the researchers examined the effect of fatty acid metabolites on the cognitive abilities of seniors. Forty-three people participated in this study. Out of forty-three individuals, fourteen older adults had healthy, normal brain, fifteen had tau tangles or amyloid plaque buildup (both key characteristics of Alzheimer’s), and fifteen had Alzheimer’s disease.

When the researchers examined the metabolite levels in those parts of the brain that are associated with Alzheimer’s, they found six fatty acids (eicosapentaenoic acid, oleic acid, docosahexaenoic acid, linolenic acid, arachidonic acid, and linoleic acid) to be associated with Alzheimer’s.

Topics: Dementia | No Comments »

Peptide Hi1a Offers Protection against Brain Damage By Stroke

By jeremyc | March 22, 2017

New research has found the peptide Hi1a to be effective in helping prevent brain damage because of stroke.

The peptide Hi1a is obtained from the venom of the funnel web spider. It works by blocking ion channels present in the patient’s brain. These channels play an important role in brain damage after ischemic stroke, which accounts for more stroke cases than any other type of stroke. In ischemic stroke, blood is not able to flow to the brain.

It is estimated that nearly 800,000 individuals in the U.S. suffer a stroke every year. Stroke causes more cases of disability than any other health condition in the U.S. Stroke survivors commonly experience speech problems and behavioral changes. Weakness in one side of the body or paralysis is also common. All these things occur because of injury to some part of the brain because of stroke.

As of now, there’s no medication that can offer protection against this type of brain damage. However, authors of this study suggest Hi1a could be a viable protective agent. In this animal study, the researchers found that the peptide offer some degree of protection to central region of the brain that’s affected most because of lack of oxygen. This part of brain is rarely recovered because of rapid cell death due to stroke.

Topics: Stroke | No Comments »

Vitamin E and Selenium Do not Prevent Dementia, New Study Reveals

By jeremyc | March 21, 2017

Several studies have linked oxidative stress with neurodegenerative conditions like Parkinson’s disease and Alzheimer’s. That’s why antioxidant supplements are hailed as preventive agents for neurodegenerative disorders. However, a recent trial, in which researchers examined the efficacy of Vitamin E and selenium on older men, found no such evidence. According to the new trial, neither provides any therapeutic benefit.

In case of Parkinson’s, Alzheimer’s, and other neurodegenerative conditions, brain cells die gradually but irreversibly.  The exact cause of dementia is not known. However, scientists do know that oxidative stress contributes to the development of neurodegenerative disorders, including dementia.

Oxidative stress occurs when free radicals accumulate. Increase in the levels of free radicals is indicative of the body’s inability to keep a balance between antioxidants and free radicals. Presence of free radical in huge numbers leads to damage of the body’s DNA, proteins, and lipids, which in turn increases the risk of several diseases.

Some previous studies state that the balance of antioxidants and free radicals in the body might be restored by intake of antioxidants from dietary supplements. In this study, the researchers examined if Vitamin E and Selenium, both are antioxidant in nature, can help keep oxidative stress at bay and consequently offer protection against dementia in older men.

However, the researchers found that neither of the two prevents dementia.

 

 

Topics: Dementia | No Comments »

Obese Youth Two Times More Likely To Develop Liver Disease Later

By jeremyc | March 20, 2017

Obesity is linked with a higher risk of diabetes, heart disease, certain cancers, osteoarthritis, and gallbladder disease. Some studies have also linked obesity in youth to a greater risk of serious liver disease. However, until now, this link had not been analysed in depth.

Now a new study, in which data of 1.2 million men was analyzed, has confirmed that people with a high BMI (BMI stands for body mass index and it is a marker of obesity) in young years are at a greater risk of severe liver disease later.

Obesity is a huge public concern. Millions of people in the U.S. are obese. In fact, in some states, over 35 percent of people are obese. Over the years, obesity rate has significantly increased. What’s alarming is that health experts predict that obesity rate will continue to rise in future. It is estimated that nearly 1 billion people in the world will come in the category of obese by 2030.

In this study, the researchers found that young obese men were two times more likely to suffer from a liver disease in later years compared to young men with normal weight. According to researchers, earlier interventions as well as additional screening can prove highly beneficial in case of people with a greater risk of liver disease.

Topics: liver disease | No Comments »

Omega-3 Supplements Not Effective In Preventing Heart Disease in Healthy Individuals

By jeremyc | March 19, 2017

Omega-3 supplements are said to be beneficial for people who’ve had a heart attack. A new study backs this claim. However, many people with no diagnose of heart disease also take fish oil supplements or other omega-3 supplements believing omega-3s help in preventing heart disease. The recent study, however, has found no basis for this claim.

A type of polyunsaturated fatty acids, omega-3s play a key role in many bodily functions. They are involved in the process that produces hormones and are part of cell membranes.

Unlike other fats, our body is unable to produce omega-3s itself. We can only get them from foods, like nuts, fish, oil, flax seeds, and green vegetables.

As omega-3s plays an important role in functioning of the human body, many health benefits have been linked to them. They are thought to be extremely beneficial for heart health. They seem to offer protection against arrhythmias and high blood pressure and improve blood vessel function.

In this study, the researchers set out to investigate if omega-3 supplements can help prevent heart disease.

The researchers analyzed many randomized trials done to assess omega-3s effect on heart health. They also examined randomized trials which assessed the potential of fish oil supplements to manage and prevent heart disease, stroke, and several other conditions.

The researchers found that omega-3 supplements are beneficial for people who’ve had a heart failure or attack. However, they were unable to gather sufficient evidence to say convincingly that omega-3s help in prevention of heart disease in people who don’t have any heart condition.

Topics: Cardiovascular | No Comments »

Statins Increase Risk of Developing Diabetes in Older Women

By jeremyc | March 18, 2017

Statins are commonly prescribed for elderly women who have high blood cholesterol levels. However, how statins affect this group has not been thoroughly studied. A recent study suggests the risk of diabetes might be considerably higher in older women who take statins.

Statins belong to the class of drugs that lower cholesterol levels in blood. The liver is the main organ responsible for producing cholesterol. Statins work by reducing the amount of cholesterol the liver produces. It also assists the liver in removing excess cholesterol in blood.

An important compound, cholesterol is needed for many bodily functions. However, too much of cholesterol spells bad news. Excess cholesterol deposit itself in form of plaque on the walls of arteries. Plaque buildup is a serious risk factor for heart disease, which causes more deaths than any other health condition in the U.S.

For this study, the researchers went through data of more than 8,000 older women.

The researchers found that women who took statins were 33 percent more likely to develop diabetes than those who don’t use statins. The risk of developing diabetes in this group increased with higher doses of statins. Women taking statin in highest dosage were found to have a 51 percent greater risk of diabetes.

Topics: Diabetes | No Comments »

Eating vegetables and fruits linked to lower risk of stress in women

By jeremyc | March 17, 2017

A new study gives one more reason to eat several servings of fruits and vegetables daily. According to the study, the risk of stress in middle-aged women eating moderate quantity of vegetables and fruits is lower than their counterparts who eat fewer servings of fruits and vegetables.

Stress has become a universal phenomenon. It affects both physical as well as mental health. Studies have linked stress to several diseases. Recently a study revealed that risk of obesity is greater in people with chronic stress. Other studies have shown that there’s a link between stress and diabetes, high blood pressure, and heart disease.

In today’s age, avoiding stress completely is more of a wishful thinking than a possibility. Everybody experiences stress at some point in their lives, whether because of money-related issues, emotional worries, family problems, or something else.

The latest study suggests an easy yet effective way to lower the risk of stress: eating more vegetables and fruits daily.

For their research, scientists analyzed data of more than 60,000 men and women. The age of participants was 45 or more.

The researchers found that higher intake of vegetables of fruits lowered the risk of stress in both men and women. However, greater benefit was noted in women

Overall, adults eating 3-4 servings of vegetables and fruits showed a 12 percent lower risk of stress compared with adults who ate 0-1 serving. Whereas, adults who ate 5-7 servings of vegetables and fruits daily were 14 percent likely to experience stress than adults consuming 0-4 servings daily.

Women eating 5-7 servings of vegetables and fruits daily were found to be 23 percent likely to experience stress than women with an intake of 0-1 serving a day.

Topics: General Health News | No Comments »

Erectile Dysfunction Drugs Might Improve Heart Health

By jeremyc | March 16, 2017

According to a new study, male heart attack patients taking medication for erectile dysfunction medication might have lower risk of hospitalization because of heart failure compared with male heart attack patients who don’t take erectile dysfunction drugs.

Erectile dysfunction (ED for short) is typically defined as inability to achieve or sustain an erection that’s firm or long enough for sex. It is a fairly common health problem in men and can be caused by physical as well as psychological conditions. It is estimated that about 10 percent of American males aged between 40 and 70 years have erectile dysfunction.

The incidence rate of ED increases with age. While the prevalence rate of ED in men who are about 40 years of age is 22 percent, the incidence rate in 70 year old men is close to 50 percent. PDE5 inhibitors, like Viagra, Cialis, Stendra, and Levitra, are most commonly prescribed for ED.

In a recent study, the researchers looked at the effect of ED drugs on cardiovascular health of men who’ve had a heart attack. The researchers analyzed two ED drugs, PDE5 and alprostadil. In men, the risk of experiencing a heart attack increases after crossing 45.

The researchers found that the risk of being admitted to hospital for heart failure was 40 percent lower in men who were using ED drugs compared to those who weren’t.

Topics: Cardiovascular | No Comments »

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