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Cholesterol Plays a Part in Development of Alzheimers

By jeremyc | May 12, 2018

In a new study, the researchers have found that cholesterol might be playing an important part in Alzheimer’s.

Alzheimer’s disease is the most common form of dementia. This neurodegenerative disease is believed to affect no fewer than 5 million Americans. The hallmark of this disease is formation of clumps of amyloid-beta, a kind of protein, in the brain. These clumps interfere with brain function. They also kill brain cells.

Cholesterol, on the other hand, is a sticky-like substance, best known for its role in development of heart disease, as well as stroke. Cholesterol is of two types: HDL (good cholesterol) and LDL (bad cholesterol). High levels of LDL increase the risk of developing heart disease. While cholesterol plays a role in heart disease, that’s not all that it does. It is also an important constituent of cell wall.

In this research, the scientists have found that when cholesterol is present, amyloid beta was able to clump 20 times more quickly.

However, it is likely that dietary cholesterol (that is, cholesterol which we derive from food we eat) mightn’t be playing a part in Alzheimer’s. The reason behind this is that dietary cholesterol doesn’t enter our brain through the bloodstream.

Of course, high intake of dietary cholesterol has other negative impacts, particularly for your heart health. Therefore, you should make efforts to restrict its intake.

According to the scientist who did this study, it is important that the focus of further studies is on finding ways to control the role of cholesterol in Alzheimer’s and not on how we can remove it from brain.

 

 

Topics: | Alzheimer's/Dementia | No Comments »

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