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Liver Drug Shows Potential in Treating Alzheimer Disease

By jeremyc | September 2, 2018

Latest research shows an existing liver drug can help in the treatment of Alzheimer’s disease. The name of the drug in question is ursodeoxycholic acid (UDCA) and targets Alzheimer’s at the cellular level.

It is estimated that no fewer than 5.7 million individuals in America are living with Alzheimer’s. Worldwide, there are 46.8 million Alzheimer’s patients.

Alzheimer’s disease, much like other forms of dementia, develops gradually but is progressive in nature. Symptoms include, among others, memory loss, disorientation, delusion, difficulty thinking and understanding, and forgetfulness.

Current treatments focus on reducing the rate at which some of these symptoms progresses. Precisely for this reason, researchers all over the world are busy finding a more targeted treatment, one which can heal the disease at the cellular level.

Now UK researchers have found that UDCA could help treat Alzheimer’s.

In previous research, this liver drug showed potential in stopping Parkinson’s disease progression. This it achieved by improving mitochondria’s functioning.

Mitochondria are the powerhouse of cells, providing them the energy they require to divide and grow.

Often, mitochondria dysfunction is a factor in Alzheimer’s disease. Such changes occur much before than the development of protein plaques in the brain.

In this new study, the researchers noted that UDCA improved mitochondrial function in tissues collected from Alzheimer’s patients.

According to the researchers, this is a huge finding and the first one to show a drug targeting Alzheimer’s at cellular level. While more research needs to be done on this, it is very much possible that this finding could ultimately pave way to a better treatment for Alzheimer’s.

Topics: | Alzheimer's/Dementia | No Comments »

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