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Could NSAIDs Reduce Risk of Early Metastatic Relapse Post Surgery

By jeremyc | April 14, 2018

Following cancer surgery, there’s a strong chance of experiencing recurrence of tumor early. This is particularly true in case of breast cancer. Why this is so is something that’s still shrouded in mystery. However, there’s some encouraging news. In a new study, the researchers noticed that common NSAIDs (non-steroidal anti-inflammatory drugs) might reduce the risk of early recurrence of tumor post surgery.

In a number of cancer types, this includes breast cancer, doctors prefer to go for surgery to remove primary tumors.  With that said, it is common for cancer to recur following surgery.

Some patients who have undergone surgery for removal of primary tumors have an increased risk of early recurrence of tumor after surgery.

Although the reasons behind this are largely unknown, latest research has come up with encouraging findings. In this study, the researchers noted that when mice that had undergone surgery for removal of tumors were given NSAID to reduce pain and inflammation, they had lower risk of early relapse post-operation.

Medical professionals have long been grappling with the question that does surgery for removal of primary tumors trigger metastases. As of now a clear casual link between the two has not been established. However, studies done on this subject show that the risk of early relapses is highest between 12-18 months following surgery.

What’s more, an analysis done in 2010, involving more than 300 women, all of whom had undergone mastectomy, revealed that the incidences of early relapse were fewer among women who were given NSAIDs for managing post-surgical pain, compared to those where weren’t given NSAIDs.

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