« | Home | »

Antihypertensive Drug Might Treat Parkinson Disease

By jeremyc | June 29, 2018

A new treatment for Parkinson’s disease might be on the horizon. In a new study, the researchers tested Isradipine, a high blood pressure drug, for Parkinson’s. This was the first study, involving in vitro tests, to explore whether Isradipine might be effective against Parkinson’s disease. The results of this study are encouraging.

Isradipine is used for lowing blood pressure. It falls in the class of drugs known as calcium-channel inhibitors. Drugs belonging to this class, including Isradipine, work by dilating the arteries. However previous studies had hinted at an additional use of Isradipine—treating Parkinson’s.

Studies done earlier had found lower than normal Parkinson’s rate among those individuals who used Isradipine. As these studies were observational in nature, causation was not proved.

In Parkinson’s, the neurons responsible for producing dopamine are affected. Further tests done on Isradipine showed that it helps protect these very neurons.

In this study involving in vitro tests, the scientists are able to prove that this drug protects neurons that produce dopamine in mice.

The next step is to conduct a large-scale human trial. As a matter of fact, such a trial is currently underway in the U.S. If the results of this trial are encouraging, in near future we might have a new treatment for Parkinson’s.

Topics: | Parkinson's Disease | No Comments »

Comments are closed.