Advicor 500/20mgand/or alternativesChemical Ingredient: Niacin/Lovastatin
What is a generic medication?
Generic medications are significantly discounted copies of brand name medication that have the same active ingredients, intended use, dosage, side effects, effects, and route of administration as the original brand name medication. In other words, generic medications have the same pharmacological effects as their brand-name counterparts. Over half of all prescribed medications are for generic medications.
No generic is available for Advicor 500/20mg.
- Manufactured by Abbott Laboratories
- Product of United States • Shipped from United States
- Prescription Required
No generic is available for Advicor 500/20mg.
This product is currently unavailable
Advicor Drug Information
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Advicor Drug Information
This combination medication is used along with a proper diet to help lower "bad" cholesterol and fats (such as LDL, triglycerides) and raise "good" cholesterol (HDL) in the blood. Niacin is also known as vitamin B3 (nicotinic acid), one of the B vitamins. It works by reducing the amount of cholesterol made by the liver and by helping the body remove fats from the blood. Lovastatin belongs to a group of drugs known as "statins." It works by reducing the amount of cholesterol made by the liver. Advicor 500/20mg is prescribed after the use of one drug (niacin or lovastatin) has not been fully successful at lowering cholesterol. In addition to eating a proper diet (such as a low-cholesterol/low-fat diet), other lifestyle changes that may help Advicor 500/20mg work better include exercising, drinking less alcohol, losing weight if overweight, and stopping smoking. Consult your doctor for more details. Lowering "bad" cholesterol and triglycerides and raising good cholesterol decreases the risk of heart disease and helps prevent strokes and heart attacks. Lowering triglycerides in people with very high triglyceride blood levels may also decrease the risk of pancreas disease (pancreatitis).
How to Use Advicor
Take Advicor 500/20mg by mouth with a low-fat snack as directed by your doctor, usually once daily at bedtime. Taking Advicor 500/20mg with food will increase its absorption and help reduce side effects (such as flushing, stomach upset). Do not crush or chew extended-release tablets. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split the tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing. To lessen the chance of flushing, avoid alcohol, hot beverages, and spicy foods near the time you take Advicor 500/20mg. Taking a plain aspirin (non-enteric coated, 325 milligrams) or a nonsteroidal anti-inflammatory drug (such as ibuprofen, 200 milligrams) 30 minutes before taking Advicor 500/20mg may help prevent flushing. Ask your doctor if this treatment is right for you (especially if you are also taking a blood thinner such as warfarin). The niacin in Advicor 500/20mg is an extended-release form. Your doctor may instruct you to take the individual extended-release niacin first until you reach the right dose and then switch you over to this combination product. Niacin is also available in other formulations (such as immediate- and sustained-release). Do not switch other strengths, brands, or forms of niacin with Advicor 500/20mg because doing so may cause severe liver problems. The Dosage of Advicor 500/20mg is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Avoid eating grapefruit or drinking grapefruit juice while using Advicor 500/20mg unless your doctor instructs you otherwise. Grapefruit can increase the amount of Advicor 500/20mg in your bloodstream. Consult your doctor or pharmacist for more details. If you also take certain other drugs to lower your cholesterol (bile acid-binding resins such as cholestyramine or colestipol), take Advicor 500/20mg at least 1 hour before or at least 4 hours after taking these medications. These products can react with Advicor 500/20mg, preventing its full absorption. Take Advicor 500/20mg regularly in order to get the most benefit from it. Remember to take it at the same time each day. If you have not taken Advicor 500/20mg for an extended period (more than 7 days), consult your doctor or pharmacist for instructions on restarting it. You may need to restart your medication at a lower dose and slowly increase the dose over several weeks. It is important to continue taking Advicor 500/20mg even if you feel well. Most people with high cholesterol or triglycerides do not feel sick. It may take up to 4 weeks before you get the full benefit of Advicor 500/20mg.
Before taking Advicor 500/20mg, tell your doctor or pharmacist if you are allergic to niacin or lovastatin; or if you have any other allergies. Advicor 500/20mg may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using Advicor 500/20mg, tell your doctor or pharmacist your medical history,liver disease, kidney disease, alcohol use, stomach/intestinal ulcer, bleeding problems (such as low platelets), low levels of phosphate in the blood, gout. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Advicor 500/20mg may make you dizzy. Alcohol or marijuana (cannabis) can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Talk to your doctor if you are using marijuana (cannabis). Limit alcoholic beverages. Daily use of alcohol may increase your risk for liver problems, especially when combined with Advicor 500/20mg. Ask your doctor or pharmacist for more information. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. This is especially important if you are also taking medication to lower your blood pressure. If you have diabetes, Advicor 500/20mg may increase your blood sugar. Check your blood sugar regularly as directed and share the results with your doctor. Tell your doctor right away if you have symptoms of high blood sugar such as increased thirst/urination. Your doctor may need to adjust your diabetes medication, exercise program, or diet. Older adults may be more sensitive to the side effects of Advicor 500/20mg, especially muscle problems. Advicor 500/20mg must not be used during pregnancy. Lovastatin may harm an unborn baby. Therefore, it is important to prevent pregnancy while taking Advicor 500/20mg. Consult your doctor for more details and to discuss the use of reliable forms of birth control (such as condoms, birth control pills) while taking Advicor 500/20mg. If you become pregnant or think you may be pregnant, tell your doctor right away. Advicor 500/20mg passes into breast milk and may have undesirable effects on a nursing infant. Breast-feeding while using Advicor 500/20mg is not recommended. Consult your doctor before breast-feeding.
If you miss a dose of Advicor 500/20mg, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.
See also How to Use section. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval."blood thinners" (such as warfarin), gemfibrozil, vitamin or dietary products that contain niacin or nicotinamide. Other medications can affect the removal of lovastatin from your body, which may affect how lovastatin works. Examples include certain azole antifungals (such as itraconazole, ketoconazole, posaconazole, voriconazole), cobicistat, colchicine, cyclosporine, delavirdine, macrolide antibiotics (such as clarithromycin, erythromycin), nefazodone, HIV protease inhibitors (such as lopinavir, ritonavir), hepatitis C virus protease inhibitors (such as boceprevir, telaprevir), telithromycin, among others. Do not take any red yeast rice products while you are taking niacin/lovastatin since those products may also contain lovastatin. Taking niacin/lovastatin and red yeast rice products together can increase your risk of serious muscle and liver problems. Advicor 500/20mg may interfere with certain laboratory tests (such as urine or blood catecholamines, copper-based urine glucose tests). Make sure laboratory personnel and all your doctors know you use Advicor 500/20mg.
Advicor Side Effects
Flushing (warmth/redness/itching/tingling of the skin, especially of the face/neck), sweating, headache, dizziness, or chills may occur within 2 to 4 hours after taking Advicor 500/20mg. Flushing may persist for a few hours. These effects should improve or go away after several weeks as your body adjusts to the medication. Stomach upset, nausea, vomiting, or diarrhea may also occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed Advicor 500/20mg because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using Advicor 500/20mg do not have serious side effects. A very small number of people taking lovastatin may have mild memory problems or confusion. If these rare effects occur, talk to your doctor. Rarely, statins may cause or worsen diabetes. Talk to your doctor about the benefits and risks.toe/joint pain, fainting, swelling ankles/feet/hands, shortness of breath, fast heartbeat, easy bruising/bleeding, black/tarry stools, vomit that looks like coffee grounds. Advicor 500/20mg may rarely cause muscle problems (which can rarely lead to very serious conditions called rhabdomyolysis and autoimmune myopathy).muscle pain/tenderness/weakness (especially with fever or unusual tiredness), signs of kidney problems (such as change in the amount of urine). Advicor 500/20mg may rarely cause liver problems. If you notice any of the following rare but serious side effects,yellowing eyes/skin, dark urine, persistent nausea/vomiting, severe stomach/abdominal pain. A very serious allergic reaction to Advicor 500/20mg is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction,rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.List of Advicor side effects
Store at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard Advicor 500/20mg when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.
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