Climara 0.075mg/24Hr(Estradiol Hemihydrate)
Please Note: This patch is normally applied once weekly. Four patches provides a one month supply. Do not cut. Each patch contains a total of 3.8mg of estradiol providing 0.05mg/24 hour period.
Marketed as Progynova TS 50 in United Kingdom
Please Note: This patch is normally applied once weekly. Four patches provides a one month supply. Do not cut. Each patch contains a total of 7.6mg of estradiol providing 0.01mg/24 hour period.
Climara Drug Information
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How Long Does It Take to Receive My Climara Order?
You can easily place an order on our website in under 5 minutes. First you need to set up an account with us, create a payment method, and send us your prescriptions. Alternatively, you can order by downloading our order form or by placing an order over the phone. Delivery can take approximately 2 weeks to North America, and 4 weeks to other countries.
Climara 0.075mg/24Hr is a female hormone (estrogen). Climara 0.075mg/24Hr is used by women to help reduce symptoms of menopause (such as hot flashes, vaginal dryness). These symptoms are caused by the body making less estrogen. If you are using Climara 0.075mg/24Hr to treat symptoms only in and around the vagina, products applied directly inside the vagina should be considered before medications that are taken by mouth, absorbed through the skin, or injected. Climara 0.075mg/24Hr may also be used by women who are not able to produce enough estrogen (for example, due to hypogonadism, primary ovarian failure). Certain estrogen products may also be used by women after menopause to prevent bone loss (osteoporosis). However, there are other medications (such as raloxifene, bisphosphonates including alendronate) that are also effective in preventing bone loss and may be safer. These medications should be considered for use before estrogen treatment.
Estrogens, either used alone or with another hormone (progestin), have rarely caused very serious side effects. Discuss the risks and benefits of hormone treatment with your doctor. Estrogens should not be used to prevent heart disease or dementia. Estrogens can increase the risk of cancer of the uterus (endometrial cancer). Taking a progestin as directed by your doctor can help decrease this risk. Tell your doctor right away if you have any unusual vaginal bleeding. In postmenopausal women, estrogens, taken with or without a progestin, increase the risk of cancer of the breast/ovaries, stroke, dementia, and serious blood clots. When used along with a progestin, estrogens also increase the risk of heart disease (such as heart attacks). The risk for serious side effects may depend on the dose of estrogen and the length of time Climara 0.075mg/24Hr is used. Therefore, Climara 0.075mg/24Hr should be used at the lowest effective dose and for the shortest amount of time. Discuss the use of Climara 0.075mg/24Hr with your doctor and check with him/her regularly (for example, every 3 to 6 months) to see if you still need to use Climara 0.075mg/24Hr. If you will be using Climara 0.075mg/24Hr long-term, you should have regular complete physical exams (for example, once a year) as directed by your doctor. See also Notes section.
How to Use Climara
Read the Patient Information Leaflet if available from your pharmacist before you start using Climara 0.075mg/24Hr and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Peel off the backing from the patch and apply the patch to a clean, dry area of the lower stomach or the top of the buttocks. Press the patch firmly in place for about 10 seconds to make sure it stays on. Do not apply the patch on the breast or on oily, broken, or irritated skin. Avoid applying the patch to areas of the skin where it might be easily rubbed off (such as the waistline). Use Climara 0.075mg/24Hr as directed by your doctor. The patch is usually worn for 1 week and then replaced. Follow the dosing schedule carefully. The Dosage of Climara 0.075mg/24Hr is based on your medical condition and response to treatment. When replacing your patch, make sure to apply the new patch to a different area. Wait at least 1 week before applying a patch to the same area. Fold the old patch in half with the sticky side together and throw away in the trash away from children and pets. Do not flush the patch down the toilet. If a patch falls off, reapply it to a different area. If the patch does not stick completely, then apply a new patch and wear it for the rest of the 7-day period. Do not wear 2 patches at the same time. Use Climara 0.075mg/24Hr regularly to get the most benefit from it. To help you remember, change the patch on the same day each week. It may help to mark your calendar as a reminder. Tell your doctor if your condition does not improve or if it worsens.
Before using estradiol, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Climara 0.075mg/24Hr may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using Climara 0.075mg/24Hr, tell your doctor or pharmacist your medical history,vaginal bleeding of unknown cause, certain cancers (such as breast cancer, cancer of the uterus/ovaries), blood clots, stroke, heart disease (such as heart attack), liver disease, kidney disease, family medical history (especially breast lumps, cancer, blood clots), family or personal history of a certain swelling disorder (angioedema), blood clotting disorders (such as protein C or protein S deficiency), high blood pressure, diabetes, high cholesterol/triglyceride levels, obesity, lupus, underactive thyroid (hypothyroidism), mineral imbalance (low or high level of calcium in the blood), a certain hormone problem (hypoparathyroidism), uterus problems (such as fibroids, endometriosis), gallbladder disease, asthma, seizures, migraine headaches, a certain blood disorder (porphyria), mental/mood disorders (such as dementia, depression). Do not smoke or use tobacco. Estrogens combined with smoking further increases your risk of stroke, blood clots, high blood pressure, and heart attack, especially in women older than 35. Tell your doctor if you just had or will be having surgery, or if you will be confined to a chair or bed for a long time (such as a long plane flight). These conditions increase your risk of getting blood clots, especially if you are taking an estrogen product. You may need to stop Climara 0.075mg/24Hr for a time or take special precautions. Climara 0.075mg/24Hr may cause blotchy, dark areas on your face and skin (melasma). Sunlight may worsen this effect. Limit your time in the sun. Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors. If you are nearsighted or wear contact lenses, you may develop vision problems or trouble wearing your contact lenses. Contact your eye doctor if these problems occur. If you are going to have an MRI test, tell testing personnel that you are using this patch. Some patches may contain metals that can cause serious burns during an MRI. Ask your doctor whether you will need to remove your patch before the test and apply a new patch afterward, and how to do so properly. Children may be more sensitive to the side effects of Climara 0.075mg/24Hr. It may affect their growth/development. Discuss the possible effects of Climara 0.075mg/24Hr with the doctor, and monitor your child's growth periodically. Climara 0.075mg/24Hr must not be used during pregnancy. If you become pregnant or think you may be pregnant, tell your doctor right away. Climara 0.075mg/24Hr passes into breast milk. It may reduce the quality and amount of breast milk produced. Consult your doctor before breast-feeding.
If you forget to replace a patch at the scheduled time, replace it as soon as you remember. Do not use more than one patch at a time.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.aromatase inhibitors (such as anastrozole, exemestane, letrozole), fulvestrant, ospemifene, raloxifene, tamoxifen, toremifene, tranexamic acid. Climara 0.075mg/24Hr may interfere with certain laboratory tests (including metyrapone test), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use Climara 0.075mg/24Hr.
Climara Side Effects
What are Climara side effects?
Side effects are physical, mental or emotional symptoms which occur in addition to or outside of the desired effect of a therapeutic treatment such as an over-the-counter or prescribed drug or medication. Side effects from Climara may occur at the beginning or at the end of treatment and may also depend on the length of time an individual remains on the treatment. Side effects, also known as adverse effects, are generally more likely to occur when starting treatment. Individuals may also experience side effects from Climara as a result of an interaction with other medications.
Side Effects of Climara
The side effects of Climara may vary in number and intensity for many different reasons. Factors such as age, weight, gender and ethnicity may influence the side effects of Climara. Also, an individual’s state of general physical health and seriousness of the disease or illness as well as an increase or decrease in dosage may lead to side effects. Further, side effects from Climara may also occur as a result of an interaction with certain herbal supplements, foods or drinks.
Prescription drug side effects can be serious and may cause patients to stop the treatment. However, when side effects from the use of a prescription drug, such as Climara, do occur a patient should consult their physician. A physician may prescribe an additional treatment in order to control the symptoms or an adjustment in the dosage may be made. In addition, changes to diet, exercise or other lifestyle activities may help to lessen the side effects of Climara.
By understanding side effects and the factors which may influence the occurrence of side effects patients are empowered to take an active role in their care. Patients who have specific questions about the side effects of Climara, or any other medication, should contact their physician. General information about Climara and the side effects associated with Climara are described in the following:
Common Climara Side Effects
- abnormal vaginal bleeding
- peripheral edema
- weight gain
- abnormal vaginal bleeding
- peripheral edema
- weight gain
- abdominal distension
- pruritus of skin
Less Frequent Climara Side Effects
- upper respiratory infection
- libido changes
- neck pain
- back pain
- skin irritation
- headache disorder
- vulvovaginal candidiasis
- cervical discharge
Rare or Very Rare Climara Side Effects
- malignant neoplasm of the ovary
- endometrial carcinoma
- neoplasm of breast
- retinal thrombosis
- pulmonary thromboembolism
- cerebrovascular accident
- thromboembolic disorder
- gallbladder obstruction
- obstructive hyperbilirubinemia
- acute pancreatitis
- malignant epithelial tumor of ovary
- nipple discharge
- ventricular premature beats
- acute myocardial infarction
- endometrial hyperplasia
- fibrocystic breast disease
- erythema multiforme
- erythema nodosum
- deep venous thrombosis
- pharyngeal edema
- general weakness
- skin rash
- vaginal discharge
- fallopian tube disorder
- pelvic pain
- body fluid retention
- galactorrhea not associated with childbirth
- mood changes
- uterine leiomyoma
- cramps in legs
- uterine cramps
- varicose veins
- dry skin
- skin pigmentation enhancement
- flu-like symptoms
- muscle spasm
- oral hypoesthesia
- tongue swelling
- ovarian cyst
Store at room temperature. Do not remove the patch from the pouch until ready for use. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard Climara 0.075mg/24Hr when it is expired or no longer needed (See How to Use section).
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