Podofilox solution is used to treat warts on the outside of the genitals. It stops the growth of the wart and the wart eventually falls off. Podofilox belongs to a group of drugs called antimitotics.
How to Use Podofilox
Read the Patient Information Leaflet if available from your pharmacist before you start using podofilox solution and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Podofilox is for use on the skin only. Only apply Podofilox to the genital warts that your doctor has identified for you. Do not use Podofilox on warts around the anus or on the mucous membranes (such as in the urethra, rectum, and vagina), inside your body, or on any other skin growths. Use Podofilox usually twice daily (once in the morning and once in the evening, every 12 hours), for 3 days in a row, followed by no treatment for the next 4 days. If the warts do not go away, you may repeat this 7-day cycle up to a total of 4 treatment weeks in a row. Follow your doctor's directions exactly. First wash the area to be treated with soap and water, and dry thoroughly. Use an applicator that comes with Podofilox, dip it into the solution just enough to wet it, but not so much that solution is dripping from the tip. Apply Podofilox only to the warts your doctor has directed you to treat. Do not apply it to the area surrounding the warts. It may help to use a hand mirror. For warts within skin folds, pull the skin fold open and apply the medication. Let the medication dry before allowing the skin folds around the warts to return to their normal position. Only use the applicator once. Do not dip it into the solution again. Throw it away in a safe place after use. Wash your hands with soap and water after each application. Do not cover the treated area with bandages or other waterproof dressings. Covering the area with cotton gauze, or cotton underwear for the genital area, is permitted. Use Podofilox regularly to get the most benefit from it. To help you remember, use a calendar to mark the days you will be applying the medication each week. Avoid getting Podofilox in the eyes/nose/mouth, on healthy skin, or on other areas as mentioned above. If the medication gets on healthy skin, wipe it off right away and wash the area thoroughly with soap and water and rinse off. If the medication gets in your eyes, nose, or mouth, flush the area with plenty of water for 15 minutes and contact your doctor. Do not apply a large amount of Podofilox or apply it to a large area. Ask your doctor or pharmacist for details. Do not use it more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase. Tell your doctor if your condition lasts after 4 weeks of treatment, or if it gets worse, or if new growths appear during treatment. Genital warts often return after treatment.
Before using podofilox, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Podofilox may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using Podofilox, tell your doctor or pharmacist your medical history. Podofilox is not a cure for genital warts. These warts are caused by a virus called human papillomavirus (HPV). Podofilox does not destroy the virus. It only helps to remove the warts, but new warts may form or old warts may return, during and after treatment. Do not have sexual intercourse on the days you have applied Podofilox. Genital warts are spread by sexual contact. Condoms (such as latex or polyurethane types) may help prevent the spread of genital warts to your partner. Consult your doctor or pharmacist for more details. Podofilox must not be used during pregnancy. It may harm an unborn baby. Discuss the use of reliable forms of birth control with your doctor. If you become pregnant or think you may be pregnant, tell your doctor right away. It is unknown if Podofilox passes into breast milk. Consult your doctor before breast-feeding.
If you miss a dose of Podofilox, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Use your next dose at the regular time. Do not double the dose to catch up.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
Podofilox Side Effects
Redness, itching, burning, and pain may occur in the treated area. If any of these effects last or get worse, or if you have bleeding, severe swelling, or severe pain, wash the medication off with soap and water. Stop using Podofilox and tell your doctor or pharmacist promptly. Remember that Podofilox has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using Podofilox do not have serious side effects. A very serious allergic reaction to Podofilox is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction,rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Store at room temperature away from high heat and open flame. Do not freeze. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard Podofilox when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
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