Premarin 0.45mg(Estrogens, Conjugated)
Please Note: Patients taking Premarin 0.9mg can save by taking 3 x Premarin 0.3mg tablets instead.
Premarin Drug Information
Are you paying too much for Premarin? Save up to 80% when purchasing your prescription drugs from Universal Drugstore. Our prescription service aspires to conveniently provide you with affordable medications at the lowest prices in Canada and internationally.
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How Long Does It Take to Receive My Premarin Order?
You can easily place an order on our website in under 5 minutes. First you need to set up an account with us, create a payment method, and send us your prescriptions. Alternatively, you can order by downloading our order form or by placing an order over the phone. Delivery can take approximately 2 weeks to North America, and 4 weeks to other countries.
Premarin 0.45mg is a female hormone. Premarin 0.45mg is used by women to help reduce symptoms of menopause (such as hot flashes, vaginal dryness). These symptoms are caused by the body making less estrogen. If you are using Premarin 0.45mg to treat symptoms only in and around the vagina, products applied directly inside the vagina should be considered before medications that are taken by mouth, absorbed through the skin, or injected. Certain estrogen products may also be used by women after menopause to prevent bone loss (osteoporosis). However, there are other medications (such as raloxifene, bisphosphonates including alendronate) that are also effective in preventing bone loss and may be safer. These medications should be considered for use before estrogen treatment. Certain estrogen products may also be used by men and women to treat cancers (certain types of prostate cancer, breast cancer that has spread to other parts of the body) and by women who are not able to produce enough estrogen (for example, due to hypogonadism, primary ovarian failure).
Estrogens, either used alone or with another hormone (progestin), have rarely caused very serious side effects. Discuss the risks and benefits of hormone treatment with your doctor. Estrogens should not be used to prevent heart disease or dementia. Estrogens can increase the risk of cancer of the uterus (endometrial cancer). Taking a progestin as directed by your doctor can help decrease this risk. Tell your doctor right away if you have any unusual vaginal bleeding. In postmenopausal women, estrogens, taken with or without a progestin, increase the risk of cancer of the breast/ovaries, stroke, dementia, and serious blood clots. When used along with a progestin, estrogens also increase the risk of heart disease (such as heart attacks). The risk for serious side effects may depend on the dose of estrogen and the length of time Premarin 0.45mg is used. Premarin 0.45mg should be used at the lowest effective dose and for the shortest amount of time. Discuss the use of Premarin 0.45mg with your doctor and check with him/her regularly (for example, every 3 to 6 months) to see if you still need to take Premarin 0.45mg. If you will be taking Premarin 0.45mg long-term, you should have regular complete physical exams (for example, once a year) as directed by your doctor. See also Notes section.
How to Use Premarin
Read the Patient Information Leaflet if available from your pharmacist before you start using Premarin 0.45mg and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take Premarin 0.45mg by mouth with or without food as directed by your doctor. You may take it with food or right after a meal to prevent stomach upset. If you are taking the extended-release tablets, do not crush, chew, or dissolve them. Doing so can release all of the drug at once, increasing the risk of side effects. Swallow the tablets whole. The Dosage of Premarin 0.45mg is based on your medical condition and response to treatment. Take Premarin 0.45mg regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day as directed. Follow your dosing schedule carefully. Do not increase your dose or take Premarin 0.45mg more often or for a longer time than directed. Tell your doctor if your condition does not improve or if it worsens.
Before taking Premarin 0.45mg, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Premarin 0.45mg may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using Premarin 0.45mg, tell your doctor or pharmacist your medical history,vaginal bleeding of unknown cause, certain cancers (such as breast cancer, cancer of the uterus/ovaries), blood clots, stroke, heart disease (such as heart attack), liver disease, kidney disease, family medical history (especially breast lumps, cancer, blood clots), family or personal history of a certain swelling disorder (angioedema), blood clotting disorders (such as protein C or protein S deficiency), high blood pressure, diabetes, high cholesterol/triglyceride levels, obesity, lupus, underactive thyroid (hypothyroidism), mineral imbalance (low or high level of calcium in the blood), a certain hormone problem (hypoparathyroidism), uterus problems (such as fibroids, endometriosis), gallbladder disease, asthma, seizures, migraine headaches, a certain blood disorder (porphyria), mental/mood disorders (such as dementia, depression). Do not smoke or use tobacco. Estrogens combined with smoking further increases your risk of stroke, blood clots, high blood pressure, and heart attack, especially in women older than 35. Tell your doctor if you just had or will be having surgery, or if you will be confined to a chair or bed for a long time (such as a long plane flight). These conditions increase your risk of getting blood clots, especially if you are taking an estrogen product. You may need to stop Premarin 0.45mg for a time or take special precautions. Premarin 0.45mg may cause blotchy, dark areas on your face and skin (melasma). Sunlight may worsen this effect. Limit your time in the sun. Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors. If you are nearsighted or wear contact lenses, you may develop vision problems or trouble wearing your contact lenses. Contact your eye doctor if these problems occur. Children may be more sensitive to the side effects of Premarin 0.45mg. It may affect their growth/development. Discuss the possible effects of Premarin 0.45mg with the doctor, and monitor your child's growth periodically. Premarin 0.45mg should not be used during pregnancy. If you become pregnant or think you may be pregnant, tell your doctor right away. Premarin 0.45mg passes into breast milk. It may reduce the quality and amount of breast milk produced. Consult your doctor before breast-feeding.
If you miss a dose of Premarin 0.45mg, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.aromatase inhibitors (such as anastrozole, exemestane, letrozole), fulvestrant, ospemifene, raloxifene, tamoxifen, toremifene, tranexamic acid. Premarin 0.45mg may interfere with certain laboratory tests (including metyrapone test), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use Premarin 0.45mg.
Premarin Side Effects
What are Premarin side effects?
Side effects are physical, mental or emotional symptoms which occur in addition to or outside of the desired effect of a therapeutic treatment such as an over-the-counter or prescribed drug or medication. Side effects from Premarin may occur at the beginning or at the end of treatment and may also depend on the length of time an individual remains on the treatment. Side effects, also known as adverse effects, are generally more likely to occur when starting treatment. Individuals may also experience side effects from Premarin as a result of an interaction with other medications.
Side Effects of Premarin
The side effects of Premarin may vary in number and intensity for many different reasons. Factors such as age, weight, gender and ethnicity may influence the side effects of Premarin. Also, an individual’s state of general physical health and seriousness of the disease or illness as well as an increase or decrease in dosage may lead to side effects. Further, side effects from Premarin may also occur as a result of an interaction with certain herbal supplements, foods or drinks.
Prescription drug side effects can be serious and may cause patients to stop the treatment. However, when side effects from the use of a prescription drug, such as Premarin, do occur a patient should consult their physician. A physician may prescribe an additional treatment in order to control the symptoms or an adjustment in the dosage may be made. In addition, changes to diet, exercise or other lifestyle activities may help to lessen the side effects of Premarin.
By understanding side effects and the factors which may influence the occurrence of side effects patients are empowered to take an active role in their care. Patients who have specific questions about the side effects of Premarin, or any other medication, should contact their physician. General information about Premarin and the side effects associated with Premarin are described in the following:
Common Premarin Side Effects
- headache disorder
- abdominal distension
- acute abdominal pain
Less Frequent Premarin Side Effects
- back pain
- weight gain
- vulvovaginal candidiasis
- cramps in legs
- increased appetite
- vaginal discharge
- peripheral edema
- body fluid retention
- general weakness
- symptoms of anxiety
Rare or Very Rare Premarin Side Effects
- uterine leiomyoma
- malignant neoplasm of the ovary
- endometrial carcinoma
- neoplasm of breast
- retinal thrombosis
- acute myocardial infarction
- pulmonary thromboembolism
- cerebrovascular accident
- thromboembolic disorder
- venous thrombosis
- upper respiratory infection
- asthma exacerbation
- ischemic colitis
- gallbladder obstruction
- acute pancreatitis
- unspecified lump in breast
- nipple discharge
- endometrial hyperplasia
- abnormal vaginal bleeding
- erythema multiforme
- erythema nodosum
- involuntary muscle movement
- skin rash
- mood changes
- libido changes
- weight loss
- pruritus of skin
- pelvic pain
Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard Premarin 0.45mg when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
IMPORTANT DISCLAIMER: All medical content is supplied by a third-party company who is independent from this web site. As such, this web site cannot guarantee the reliability, accuracy, and /or medical efficacy of the information provided. In all circumstances, you should seek the advice of a health professional pertaining to drug, treatment and/or medical condition advice. Note that not all products are shipped by our contracted Canadian pharmacy. This website contracts with dispensaries around the world that ship products directly to our customers. Some of the jurisdiction include but are not limited to United Kingdom, Europe, Turkey, India, Canada, Vanuatu, Mauritius, and USA. The items within your order may be shipped from any one of these jurisdictions depending on the availability and cost of the products at the time you place your order. The products are sourced from these countries as well as others. Please note that the product appearance may vary from actual product received depending on availability.