Stivarga 40mg
(Regorafenib)-
All Strengths
-
40mg
What is a generic medication?
Generic medications are significantly discounted copies of brand name medication that have the same active ingredients, intended use, dosage, side effects, effects, and route of administration as the original brand name medication. In other words, generic medications have the same pharmacological effects as their brand-name counterparts. Over half of all prescribed medications are for generic medications.
Stivarga Drug Information
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How Long Does It Take to Receive My Stivarga Order?
You can easily place an order on our website in under 5 minutes. First you need to set up an account with us, create a payment method, and send us your prescriptions. Alternatively, you can order by downloading our order form or by placing an order over the phone. Delivery can take approximately 2 weeks to North America, and 4 weeks to other countries.
Stivarga Overview
Regorafenib is used to treat cancer of the colon and rectum. It is also used to treat liver cancer and a certain cancer of the digestive system (gastrointestinal stromal tumor). It works by slowing or stopping the growth of cancer cells.
Stivarga Warnings
Regorafenib has rarely caused very serious (possibly fatal) liver disease, especially in the first 2 months of treatment. People of Asian descent are at greater risk. Your doctor will monitor your liver function before and during treatment with Stivarga 40mg. Tell your doctor right away if you develop new or worsening symptoms of liver disease, such as nausea/vomiting that doesn't stop, severe stomach/abdominal pain, dark urine, yellowing eyes/skin.
How to Use Stivarga
Read the Patient Information Leaflet if available from your pharmacist before you start taking regorafenib and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take Stivarga 40mg by mouth with a low-fat meal as directed by your doctor, usually once daily for 21 days, then stopping the medication for 7 days. This is one cycle of treatment. Continue taking the medication this way as directed by your doctor. Swallow the medication whole. Do not crush, chew, or split the tablets. The Dosage of Stivarga 40mg is based on your medical condition and response to treatment. Do not increase your dose or use Stivarga 40mg more often or for longer than prescribed. Your condition will not improve any faster, and your risk of serious side effects will increase. Take Stivarga 40mg regularly to get the most benefit from it. Remember to take it at the same time each day that you are scheduled to take it. Avoid eating grapefruit or drinking grapefruit juice while using Stivarga 40mg unless your doctor or pharmacist says you may do so safely. Grapefruit can increase the chance of side effects with this medicine. Ask your doctor or pharmacist for more details. Since Stivarga 40mg can be absorbed through the skin and lungs and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle Stivarga 40mg or breathe the dust from the tablets.
Stivarga Precautions
Before taking regorafenib, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Stivarga 40mg may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using Stivarga 40mg, tell your doctor or pharmacist your medical history,liver problems, high blood pressure, heart disease (such as heart attack, chest pain), bleeding problems (such as bleeding of the stomach/intestines), blood vessel problems (such as an aneurysm or a tear/break in the aorta or other blood vessels), recent major surgery/injury. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Your doctor or dentist may tell you to stop taking regorafenib at least 2 weeks before surgery. Stivarga 40mg may cause wounds to heal more slowly. Follow all instructions about when to stop or restart Stivarga 40mg. Tell your health care professional that you are using regorafenib before having any immunizations/vaccinations. Avoid contact with people who have recently received live vaccines (such as flu vaccine inhaled through the nose). To lower the chance of getting cut, bruised, or injured, use caution with sharp objects like razors and nail cutters, and avoid activities such as contact sports. Older adults may be at greater risk for high blood pressure while using Stivarga 40mg. Tell your doctor if you are pregnant or plan to become pregnant. You should not become pregnant while using regorafenib. Regorafenib may harm an unborn baby. Both women and men should ask about reliable forms of birth control while using Stivarga 40mg and for 2 months after stopping treatment. If you or your partner becomes pregnant, talk to your doctor right away about the risks and benefits of Stivarga 40mg. Since Stivarga 40mg can be absorbed through the skin and lungs and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle Stivarga 40mg or breathe the dust from the tablets. It is unknown if Stivarga 40mg passes into breast milk. Because of the possible risk to the infant, breast-feeding while using Stivarga 40mg and for 2 weeks after stopping treatment is not recommended. Consult your doctor before breast-feeding.
Stivarga Misdose
If you miss a dose of Stivarga 40mg and remember on the same day, take it as soon as you remember. If you remember on the next day, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.
Stivarga Interactions
See also How to Use section. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.irinotecan, other drugs that can cause bleeding/bruising (including antiplatelet drugs such as clopidogrel, NSAIDs such as ibuprofen, "blood thinners" such as warfarin). Aspirin can increase the risk of bleeding when used with Stivarga 40mg. However, if your doctor has directed you to take low-dose aspirin for heart attack or stroke prevention (usually 81-162 milligrams a day), you should continue taking it unless your doctor instructs you otherwise. Ask your doctor or pharmacist for more details. Other medications can affect the removal of regorafenib from your body, which may affect how regorafenib works. Examples include nefazodone, ritonavir, St. John's wort, telithromycin, azole antifungals (such as ketoconazole, itraconazole), macrolide antibiotics (such as clarithromycin), HIV protease inhibitors (such as nelfinavir), rifamycins (such as rifabutin, rifampin), drugs used to treat seizures (such as phenytoin), among others.
Stivarga Side Effects
What are Stivarga side effects?
Side effects are physical, mental or emotional symptoms which occur in addition to or outside of the desired effect of a therapeutic treatment such as an over-the-counter or prescribed drug or medication. Side effects from Stivarga may occur at the beginning or at the end of treatment and may also depend on the length of time an individual remains on the treatment. Side effects, also known as adverse effects, are generally more likely to occur when starting treatment. Individuals may also experience side effects from Stivarga as a result of an interaction with other medications.
Side Effects of Stivarga
The side effects of Stivarga may vary in number and intensity for many different reasons. Factors such as age, weight, gender and ethnicity may influence the side effects of Stivarga. Also, an individual’s state of general physical health and seriousness of the disease or illness as well as an increase or decrease in dosage may lead to side effects. Further, side effects from Stivarga may also occur as a result of an interaction with certain herbal supplements, foods or drinks.
Prescription drug side effects can be serious and may cause patients to stop the treatment. However, when side effects from the use of a prescription drug, such as Stivarga, do occur a patient should consult their physician. A physician may prescribe an additional treatment in order to control the symptoms or an adjustment in the dosage may be made. In addition, changes to diet, exercise or other lifestyle activities may help to lessen the side effects of Stivarga.
By understanding side effects and the factors which may influence the occurrence of side effects patients are empowered to take an active role in their care. Patients who have specific questions about the side effects of Stivarga, or any other medication, should contact their physician. General information about Stivarga and the side effects associated with Stivarga are described in the following:
Common Stivarga Side Effects
Severe
- impaired wound healing
- hemorrhage
- hypophosphatemia
- anemia
- thrombocytopenic disorder
- hypocalcemia
- hypokalemia
- hyponatremia
- increased alanine transaminase
- increased aspartate transaminase
- elevated serum amylase
- elevated serum lipase
Less Severe
- hypertension
- general weakness
- fatigue
- anorexia
- palmar-plantar erythrodysesthesia
- diarrhea
- stomatitis
- weight loss
- infection
- voice change
- fever
- skin rash
- headache disorder
- pain
- nausea
- acute abdominal pain
- proteinuria
- hyperbilirubinemia
Less Frequent Stivarga Side Effects
Severe
- abnormal hepatic function tests
- myocardial ischemia
- acute myocardial infarction
- hepatic failure
- pancreatitis
Less Severe
- alopecia
- muscle rigidity
- hypothyroidism
- maculopapular rash
- muscle spasm
Rare or Very Rare Stivarga Side Effects
Severe
- posterior reversible encephalopathy syndrome
- gastrointestinal perforation
- gastrointestinal fistula
- toxic epidermal necrolysis
- erythema multiforme
- Stevens-Johnson syndrome
- hepatocellular damage
- hypersensitivity drug reaction
- hypertensive crisis
- nephrotic syndrome
- heart failure
- arterial dissection
- arterial aneurysm
Less Severe
Stivarga Storage
Store at room temperature away from light and moisture. Keep the medication in the original bottle with the desiccant to protect against moisture. Do not store in the bathroom. Discard any remaining tablets 7 weeks after opening the bottle. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard Stivarga 40mg when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
IMPORTANT DISCLAIMER: All medical content is supplied by a third-party company who is independent from this web site. As such, this web site cannot guarantee the reliability, accuracy, and /or medical efficacy of the information provided. In all circumstances, you should seek the advice of a health professional pertaining to drug, treatment and/or medical condition advice. Note that not all products are shipped by our contracted Canadian pharmacy. This website contracts with dispensaries around the world that ship products directly to our customers. Some of the jurisdiction include but are not limited to United Kingdom, Europe, Turkey, India, Canada, Vanuatu, Mauritius, and USA. The items within your order may be shipped from any one of these jurisdictions depending on the availability and cost of the products at the time you place your order. The products are sourced from these countries as well as others. Please note that the product appearance may vary from actual product received depending on availability.