Synvisc-One 8mg/mL(Hylan G-F 20)
Synvisc One 8mg/mLInjection
Marketed as Synvisc ONE 48mg/6mL in United Kingdom
Synvisc-One Drug Information
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How Long Does It Take to Receive My Synvisc-One Order?
You can easily place an order on our website in under 5 minutes. First you need to set up an account with us, create a payment method, and send us your prescriptions. Alternatively, you can order by downloading our order form or by placing an order over the phone. Delivery can take approximately 2 weeks to North America, and 4 weeks to other countries.
Synvisc-One 8mg/mL is used to treat knee pain in patients with joint inflammation (osteoarthritis). It is usually used in patients who have not responded to other treatments such as acetaminophen, exercise, or physical therapy. Hyaluronate (also known as hyaluronan) is similar to a substance that occurs naturally in the joints. It may work by acting as a lubricant and shock absorber in the joint, helping the knee to move smoothly, thereby lessening pain.
How to Use Synvisc-One
Read the Patient Information Leaflet provided by your health care professional before you start using hyaluronate and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Your doctor will give Synvisc-One 8mg/mL by injection into the affected joint, usually once a week. Skin disinfectants that contain ammonium salts (such as benzalkonium chloride) should not be used to prepare the injection site. Your doctor may need to remove extra fluid from the joint before injecting the medicine. Dosage of Synvisc-One 8mg/mL is based on your medical condition and response to treatment. Hyaluronate should not be injected into a vein or artery because increased side effects may occur. After receiving an injection of hyaluronate, you should avoid any activities that put stress on your knee (such as jogging, tennis, heavy lifting, standing on your feet for more than an hour) for 48 hours. Also, after the injection, you may experience increased pain and swelling in the knee at first. If the pain or swelling continues or worsens, talk to your doctor promptly. It is important to have Synvisc-One 8mg/mL injected on schedule. It may take up to 3 injections before the full benefits of Synvisc-One 8mg/mL occur. Tell your doctor if your condition lasts or gets worse.
Before using hyaluronate, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. For some brands, also tell your doctor or pharmacist if you are allergic to bird proteins, feathers, or egg products. Synvisc-One 8mg/mL may contain inactive ingredients (such as latex found in the rubber syringe cap of some brands), which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using Synvisc-One 8mg/mL, tell your doctor or pharmacist your medical history,knee joint infections, skin infections/problems in the area around the injection site, circulation problems in the legs. During pregnancy, Synvisc-One 8mg/mL should be used only when clearly needed. Discuss the risks and benefits with your doctor. It is unknown whether Synvisc-One 8mg/mL passes into breast milk. Consult your doctor before breast-feeding.
It is important to get each dose of Synvisc-One 8mg/mL as scheduled. If you miss a dose of Synvisc-One 8mg/mL, ask your doctor or pharmacist right away for a new dosing schedule.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
Synvisc-One Side Effects
What are Synvisc-One side effects?
Side effects are physical, mental or emotional symptoms which occur in addition to or outside of the desired effect of a therapeutic treatment such as an over-the-counter or prescribed drug or medication. Side effects from Synvisc-One may occur at the beginning or at the end of treatment and may also depend on the length of time an individual remains on the treatment. Side effects, also known as adverse effects, are generally more likely to occur when starting treatment. Individuals may also experience side effects from Synvisc-One as a result of an interaction with other medications.
Side Effects of Synvisc-One
The side effects of Synvisc-One may vary in number and intensity for many different reasons. Factors such as age, weight, gender and ethnicity may influence the side effects of Synvisc-One. Also, an individual’s state of general physical health and seriousness of the disease or illness as well as an increase or decrease in dosage may lead to side effects. Further, side effects from Synvisc-One may also occur as a result of an interaction with certain herbal supplements, foods or drinks.
Prescription drug side effects can be serious and may cause patients to stop the treatment. However, when side effects from the use of a prescription drug, such as Synvisc-One, do occur a patient should consult their physician. A physician may prescribe an additional treatment in order to control the symptoms or an adjustment in the dosage may be made. In addition, changes to diet, exercise or other lifestyle activities may help to lessen the side effects of Synvisc-One.
By understanding side effects and the factors which may influence the occurrence of side effects patients are empowered to take an active role in their care. Patients who have specific questions about the side effects of Synvisc-One, or any other medication, should contact their physician. General information about Synvisc-One and the side effects associated with Synvisc-One are described in the following:
Common Synvisc-One Side Effects
- knee inflammation
- injection site sequelae
Less Frequent Synvisc-One Side Effects
Rare or Very Rare Synvisc-One Side Effects
- infectious disorder of joint
- thrombocytopenic disorder
- lip hypertrophy
- pruritus of skin
- cramps in legs
- skin rash
- headache disorder
- peripheral edema
Not applicable. Synvisc-One 8mg/mL is given in a clinic and will not be stored at home.
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