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What Is Dexilant Used For?

Key Takeaways

  • Dexilant is a prescription medication used to treat conditions caused by excess stomach acid, including gastroesophageal reflux disease (GERD) and erosive esophagitis.
  • The generic name of Dexilant is dexlansoprazole, and it belongs to a class of drugs called proton pump inhibitors (PPIs).
  • Dexilant works by reducing the amount of gastric acid produced in the stomach.
  • It may help relieve symptoms such as heartburn, trouble swallowing, and irritation of the esophagus.
  • Like other prescription drugs, Dexilant can cause side effects and may interact with certain medications or supplements.

Understanding Dexilant and How It Works

Dexilant is the brand name for dexlansoprazole, a medication that reduces the amount of acid produced in the stomach. It belongs to a group of medications called proton pump inhibitors (PPIs).

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Proton pump inhibitors work by blocking the enzyme responsible for producing gastric acid in the stomach lining. By lowering stomach acid levels, these medications help prevent irritation and damage to the esophagus and surrounding tissues.

Dexilant is available as delayed-release capsules that contain granules designed to release the medication at different times in the digestive tract. This dual-release formulation allows the medication to control stomach acid over a longer period of time.

Dexilant was originally marketed under the brand name Kapidex before being renamed.

Conditions Dexilant Treats

Dexilant is most commonly prescribed for conditions related to excessive stomach acid. It can be used by adults and children 12 years of age and older.

Gastroesophageal Reflux Disease (GERD)

GERD is a condition where stomach acid frequently flows back into the esophagus. This acid reflux can cause symptoms such as heartburn, chest discomfort, and difficulty swallowing.

By reducing gastric acid production, Dexilant helps relieve GERD symptoms and protects the esophagus from irritation.

Erosive Esophagitis

Dexilant is also approved to treat erosive esophagitis, which occurs when stomach acid damages the lining of the esophagus.

This condition can cause pain, inflammation, and difficulty swallowing. Dexilant helps promote healing of the esophagus and may also be prescribed to maintain healing after the initial treatment period.

How Dexilant Is Taken

Dexilant is typically taken once daily, though the exact dose depends on the medical condition being treated.

The medication comes in delayed-release capsules that should be swallowed whole. For people who have difficulty swallowing capsules, the capsule can be opened and the granules sprinkled onto applesauce.

Some patients may receive the medication through other administration methods if necessary, such as mixing granules with water and using a syringe.

If a dose is missed, it should be taken as soon as possible unless it is close to the next dose. In that case, the missed dose should be skipped rather than doubling the next dose.

Dexilant should be stored at room temperature and kept out of the reach of children.

Common Side Effects of Dexilant

Most people tolerate Dexilant well, but some side effects may occur during treatment.

Common side effects include:

  • Stomach pain
  • Diarrhea
  • Nausea
  • Gas or bloating
  • Upper respiratory infections

These symptoms are typically mild and often improve as the body adjusts to the medication.

Serious Side Effects to Be Aware Of

Although uncommon, Dexilant can cause serious side effects that require medical attention.

Possible serious side effects include:

  • Low magnesium levels (hypomagnesemia)
  • Vitamin B12 deficiency with long-term use
  • Kidney problems such as nephritis
  • Bone fractures or osteoporosis with prolonged use
  • New or worsening lupus erythematosus
  • Serious allergic reactions or skin rash

People who experience symptoms such as severe stomach pain, joint pain, or unusual fatigue should seek medical advice from a healthcare provider.

Drug Interactions With Dexilant

Dexilant may interact with several medications, supplements, and herbal products.

Examples of possible drug interactions include:

  • Methotrexate
  • Warfarin
  • Digoxin
  • Tacrolimus
  • Atazanavir
  • Rilpivirine
  • Nelfinavir
  • Saquinavir
  • Ketoconazole
  • Erlotinib
  • St. John’s wort

These interactions may change how the medications work or increase the risk of side effects.

A healthcare professional should review all prescription drugs, over-the-counter medications, supplements, and herbal products before starting Dexilant.

Safety Considerations and Risk Factors

Long-term use or taking high doses of proton pump inhibitors may increase the risk of certain complications.

Possible risks associated with long-term use include:

  • Bone fractures related to reduced calcium absorption
  • Low magnesium levels
  • Increased risk of stomach polyps
  • Vitamin deficiencies

People with liver disease or certain medical conditions may require dose adjustments or monitoring during treatment.

Pregnant or breastfeeding individuals should consult a healthcare provider before using Dexilant to discuss potential risks and benefits.

When to Contact a Healthcare Provider

Medical advice should be sought if symptoms worsen or new concerns develop while taking Dexilant.

A healthcare provider should be contacted if someone experiences:

  • Severe stomach pain
  • Trouble swallowing
  • Persistent heartburn despite treatment
  • Signs of kidney problems
  • Allergic reaction
  • Symptoms that suggest low magnesium levels

Healthcare professionals can determine whether symptoms are related to GERD, medication side effects, or another medical condition.

The Bottom Line

Dexilant is a proton pump inhibitor used to treat acid-related conditions such as GERD and erosive esophagitis. By reducing the amount of stomach acid produced, the medication helps relieve heartburn and promote healing of the esophagus.

While Dexilant can be effective for managing acid reflux, it may cause side effects and drug interactions in some individuals. Anyone taking this medication should follow dosing instructions carefully and seek medical advice if unusual symptoms occur.

Frequently Asked Questions

What is Dexilant prescribed for?
Dexilant is prescribed to treat acid-related conditions such as gastroesophageal reflux disease (GERD) and erosive esophagitis. The medication helps reduce stomach acid, which can relieve heartburn and allow the esophagus to heal.

Is Dexilant the same as lansoprazole?
Dexilant contains dexlansoprazole, which is closely related to lansoprazole but formulated differently. Dexlansoprazole uses a dual delayed-release mechanism designed to control stomach acid for a longer period.

How long can you take Dexilant?
The length of treatment depends on the condition being treated. Some people use Dexilant for several weeks to heal erosive esophagitis, while others may use it longer for GERD management under medical supervision.

Can Dexilant be taken with food?
Yes, Dexilant can be taken with or without food. The delayed-release capsules are designed to work regardless of meals.

What should you do if you miss a dose of Dexilant?
If a dose is missed, it should be taken as soon as possible unless it is close to the next scheduled dose. In that case, the missed dose should be skipped rather than taking two doses at the same time.

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