Folic Acid Deficiency: What are the Symptoms?

Folic acid is crucial for making red blood cells and DNA. Without enough, you might develop a deficiency leading to anemia and other health issues.

Causes of Folic Acid Deficiency

Deficiency can result from poor diet, certain medical conditions, or medication effects. Common causes include:

  • Malabsorption syndromes
  • Pregnancy and breastfeeding
  • Alcohol use
  • Medications like phenytoin and methotrexate
  • Lack of dietary folate
  • Chronic diseases and surgeries
  • Genetics

Symptoms of Folate Deficiency

Symptoms often develop gradually and can include:

  • Fatigue and weakness
  • Mouth ulcers and a swollen tongue
  • Muscle weakness
  • Loss of appetite and weight loss
  • Numbness in hands and feet
  • Pale skin and breathlessness
  • Neurological issues like depression and memory loss
  • Heart palpitations

Diagnosis and Treatment

Diagnosis is based on symptoms and confirmed with blood tests. Treatment involves dietary changes or supplements.

Prevention of Folic Acid Deficiency

Eating a balanced diet rich in folate is crucial. Foods high in folate include:

  • Leafy greens, legumes, citrus fruits
  • Liver and fortified cereals
  • Pork, poultry, and mushrooms
  • Whole grains like wheat bran

Potential Impact of Cancer on Folate Levels

Some cancers may exacerbate folate deficiency, necessitating supplements. Consult healthcare providers for tailored advice.

Sources

  • Centers for Disease Control and Prevention (CDC)
  • National Institutes of Health Office of Dietary Supplements
  • Merck Manual – Consumer Version
  • Blood Journal for research on cancer and folic acid deficiency