Boniva

Boniva Drug Information

• Boniva Overview

  Ibandronate is used to prevent and treat certain types of bone loss (osteoporosis). Osteoporosis causes bones to become thinner and break more easily. Your chance of developing osteoporosis increases after menopause, as you age, or if you take corticosteroid medications (such as prednisone) for long periods. Boniva works by slowing bone loss to help maintain strong bones and reduce the risk of broken bones (fractures). Ibandronate belongs to a class of medications called bisphosphonates.

• How to Use Boniva

  Read the Medication Guide and, if available, the Patient Information Leaflet before starting Boniva and each time you get a refill because new information may be available. Follow the instructions very closely to make sure you absorb as much of the drug as possible and reduce the risk of injury to your esophagus. If you have any questions, ask your doctor or pharmacist. Take Boniva by mouth as directed by your doctor, usually once a month on the same date each month. Choose the day of the month that best fits your schedule. Take Boniva after getting up for the day, and at least 60 minutes before taking your first food, beverage or other medication. Do not take it at bedtime or while you are still in bed. Take Boniva with a full glass (6 to 8 ounces/180 to 240 milliliters) of plain water. Do not take it with any other beverages. Do not chew or suck the tablet or keep it in your mouth to melt. Swallow the tablet whole. Then stay fully upright (sitting, standing, or walking) for at least 60 minutes and do not lie down until after your first food of the day. Wait at least 60 minutes after taking ibandronate before you eat or drink anything other than plain water and before taking any other medication by mouth. Medications such as quinapril, certain forms of didanosine (chewable/dispersible buffered tablets or pediatric oral solution), sucralfate, and bismuth subsalicylate may interfere with the absorption of ibandronate. Calcium or iron supplements, vitamins with minerals, and antacids containing calcium, magnesium or aluminum, as well as foods such as dairy products (such as milk, yogurt), mineral water, and calcium-enriched juice, may also interfere with absorption. Do not take these products for at least 60 minutes after taking ibandronate. Take Boniva regularly to get the most benefit from it. Remember to take it on the same day each month. It may help to mark your calendar with a reminder. Talk to your doctor about the risks and benefits of long-term use of Boniva. Continue to take other medications for your condition as directed by your doctor.

• Boniva Precautions

  Before taking ibandronate, tell your doctor or pharmacist if you are allergic to it; or to other bisphosphonates (such as alendronate, etidronate, pamidronate, risedronate); or if you have any other allergies. Boniva may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using Boniva, tell your doctor or pharmacist your medical history,esophagus problems (such as heartburn, narrowing of the esophagus, achalasia), low blood calcium levels (hypocalcemia), inability to sit upright or stand for 60 minutes, difficult or painful swallowing, stomach/intestinal disorders (such as ulcers), severe kidney disease. Some people taking ibandronate may have serious jawbone problems. Your doctor should check your mouth before you start Boniva. Tell your dentist that you are taking Boniva before you have any dental work done. To help prevent jawbone problems, have regular dental exams and learn how to keep your teeth and gums healthy. If you have jaw pain, tell your doctor and dentist right away. Before having surgery (especially dental procedures), tell your doctor and dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Your doctor or dentist may tell you to stop taking ibandronate before your surgery. Ask for specific instructions about stopping or starting Boniva. Caution is advised if you are pregnant or planning to become pregnant in the future. Boniva may stay in your body for many years. Its effects on an unborn baby are not known. Discuss the risks and benefits with your doctor before starting treatment with ibandronate. It is unknown if Boniva passes into breast milk. Consult your doctor before breast-feeding.

• Boniva Misdose

  If you miss a dose of Boniva and your next scheduled dose is more than 7 days away, do not take the medication later in the day. Take it the next morning after you remember. Then continue taking your monthly dose in the morning on your originally chosen day of the month. If your next scheduled dose is only 1 to 7 days away, wait until your selected day to take the medication. Do not take two tablets within the same week to catch up. Consult your doctor or pharmacist if you have any questions.

• Boniva Interactions

  See also the How to Use section. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Boniva may interfere with certain laboratory tests (bone-imaging agents), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use Boniva.

• Boniva Side Effects

  What are Boniva side effects?

  Side effects are physical, mental or emotional symptoms which occur in addition to or outside of the desired effect of a therapeutic treatment such as an over-the-counter or prescribed drug or medication. Side effects from Boniva may occur at the beginning or at the end of treatment and may also depend on the length of time an individual remains on the treatment. Side effects, also known as adverse effects, are generally more likely to occur when starting treatment. Individuals may also experience side effects from Boniva as a result of an interaction with other medications.

  Side Effects of Boniva

  The side effects of Boniva may vary in number and intensity for many different reasons. Factors such as age, weight, gender and ethnicity may influence the side effects of Boniva. Also, an individual’s state of general physical health and seriousness of the disease or illness as well as an increase or decrease in dosage may lead to side effects. Further, side effects from Boniva may also occur as a result of an interaction with certain herbal supplements, foods or drinks.

  Prescription drug side effects can be serious and may cause patients to stop the treatment. However, when side effects from the use of a prescription drug, such as Boniva, do occur a patient should consult their physician. A physician may prescribe an additional treatment in order to control the symptoms or an adjustment in the dosage may be made. In addition, changes to diet, exercise or other lifestyle activities may help to lessen the side effects of Boniva.

  By understanding side effects and the factors which may influence the occurrence of side effects patients are empowered to take an active role in their care. Patients who have specific questions about the side effects of Boniva, or any other medication, should contact their physician. General information about Boniva and the side effects associated with Boniva are described in the following:

  Common Boniva Side Effects

  Severe

  Less Severe

  • upper respiratory infection
  • dyspepsia
  • back pain
  • myalgias
  • limb pain
  • flu-like symptoms
  • headache disorder
  • diarrhea
  • abdominal pain with cramps

  Less Frequent Boniva Side Effects

  Severe

  • pneumonia
  • urinary tract infection

  Less Severe

  • infection
  • hypertension
  • pharyngitis
  • bronchitis
  • tooth disorder
  • gastritis
  • constipation
  • arthritis
  • arthralgias
  • vertigo
  • dizziness
  • general weakness
  • skin rash
  • nausea
  • vomiting

  Rare or Very Rare Boniva Side Effects

  Severe

  • esophageal perforation
  • uveitis
  • ocular inflammation
  • bone pain
  • asthma exacerbation
  • anaphylaxis
  • angioedema
  • stricture of esophagus
  • esophagitis
  • atypical femoral fracture
  • hypocalcemia
  • aseptic necrosis of jaw bone
  • esophageal ulcer
  • Stevens-Johnson syndrome
  • erythema multiforme
  • bullous dermatitis
  • aseptic necrosis of bone in orofacial region

  Less Severe

  • cramps
  • insomnia

• Boniva Storage

  Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard Boniva when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.