Evoxac

The active ingredient in Evoxac is cevimeline hydrochloride, which is a cholinergic agonist. It works by binding to and activating acetylcholine receptors in your salivary glands. This helps your glands produce more saliva, making your mouth feel less dry.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Evoxac. However, the following is a synopsis of the general guidelines for the use of Evoxac:

• Drink plenty of fluids while on Evoxac. This will help your kidneys function normally and prevent dehydration.
• Evoxac is typically taken three times each day. Follow your doctor's dosage directions.

Some mild or common side effects of Evoxac include:

• Increased or excessive sweating.
• Drooling.
• Blurred vision or other vision changes.
• Upper respiratory tract infection.
• Sinus inflammation.
• Runny or stuffy nose.
• Frequent urination.
• Headache.
• Diarrhea.
• Stomach pain.

Some individuals may experience serious side effects while using Evoxac. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

• Heart rate or rhythm changes: fast or irregular heartbeat, dizziness, feeling faint or lightheaded, chest pain, and trouble breathing.
• Allergic reaction: skin rash, hives, trouble breathing, or swelling in the face, arms, and legs.
• New or worsening shortness of breath.

These are not all of the possible side effects of cevimeline. You should always consult your healthcare provider for medical advice about your health condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Evoxac, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including:

• Narrow-angle glaucoma.
• An eye condition known as iritis or uveitis.
• Asthma, chronic bronchitis, or chronic obstructive pulmonary disease (COPD).
• Heart disease, angina (chest pain), or a previous heart attack.
• A heart rhythm abnormality.
• High blood pressure (hypertension).
• Liver or kidney disease.
• A history of kidney stones or gallstones.

• Uncontrolled asthma.
• Acute iritis, narrow-angle (angle closure) glaucoma, or other conditions where pupil narrowing may cause serious complications.

Evoxac typically begins working within 30 to 90 minutes of taking a dose. Most people notice an increase in saliva or moisture in their mouth after the first few doses, but it may take a few weeks of consistent use to get the full benefit for disorders such as dry mouth caused by Sjögren's syndrome.

When Evoxac is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

• Certain antibiotics or antifungal medications.
• Some antidepressants.
• Antiviral medications that are used to treat hepatitis C and HIV/AIDS.
• Medications for the heart or blood pressure.
• Pilocarpine.

The typical dose is 30 mg by mouth three times a day.

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and only take the next dose. Do not take double or extra doses.

Store at room temperature and keep out of reach of children.

Cosette Pharmaceuticals is the company that manufactures Evoxac.

There are several generic name versions available of Evoxac.

Do not discontinue taking Evoxac (cevimeline) without first visiting your doctor. If you suddenly cease, your dry mouth symptoms may return or worsen. Depending on your condition, your doctor may advise you to reduce your dose or switch to another treatment.

It is not known if Evoxac is safe to take during pregnancy. Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.

It is not known whether this drug is secreted in breast milk. The manufacturer recommends not taking Evoxac if you are breastfeeding. Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.