Janumet

(Sitagliptin Phosphate/Metformin Hydrochloride)
  • All Strengths

  • 50/500mg

  • 50/850mg

  • 50/1000mg

Brand Choices
Janumet 50/500mg
Prescription required. Manufactured by Merck Sharp and Dohme SpA Italy. Product of India. Shipped from India.
Janumet 50/850mg
Prescription required. Manufactured by Merck Sharpe & Dohme Australia. Product of Australia. Shipped from Australia.
Janumet 50/1000mg
Prescription required. Manufactured by Merck Sharp and Dohme SpA Italy. Product of India. Shipped from India.

Janumet Helps Treat the Following Conditions:

Type 2 Diabetes

Diabetes is a serious condition related to the metabolization of sugar. Type 2 diabetes usually begins in adulthood and manifests as a resistance to – or inability to produce – insulin, which regulates blood glucose levels.

Diabetes symptoms can be managed with a combination of medication, diet, and exercise. Patients should follow a strict treatment regime to prevent long-term complications like heart and blood vessel disease, nerve damage, skin conditions, and Alzheimer’s disease.

Janumet Active Ingredient

Janumet is a combination medication with two active ingredients, sitagliptin and metformin. Sitagliptin increases levels of incretins, which increase the release of insulin after a meal and decrease the amount of sugar produced by the liver.

Metformin decreases the amount of sugar produced by the liver, which is subsequently absorbed by the digestive tract. The two active ingredients have different mechanisms of action.

Generic Janumet Alternative

Generic alternatives to Janumet are not yet available on this website.

General Drug Information

What is Janumet and What Is It Used For?

Janumet is prescribed to patients with Type 2 diabetes. Along with proper diet and exercise, Janumet helps to control high blood sugar.

Controlling high blood sugar helps to prevent a number of complications associated with diabetes: kidney damage, blindness, nerve problems, loss of limbs, sexual function problems, heart attack, and stroke.

Usage and Application

Patients who plan on sourcing Janumet online should read the medication guide prescribed by their doctor or pharmacist. Before starting treatment with Janumet, discuss the full list of prescription medications and supplements you are taking with your doctor.

Janumet should be taken exactly as prescribed by a patient’s doctor. Most patients are directed to take the medication twice a day, with meals. Dosage depends on the patient’s medical condition, response to treatment, and other medications they may be taking.

While the manufacturer cautions not to split, break, or cut the tablets before taking them, it is possible to do so with many similar drugs. Patients should ask their doctor for more information.

While taking Janumet, patients should drink plenty of water, unless directed otherwise by their doctor. To reduce the risk of side effects like upset stomach, some patients may be directed to start Janumet at a low dose, increasing it gradually.

Patients should take Janumet regularly in order to get the most benefit from the treatment. To prevent forgetting, take Janumet at the same time each day.

Those who you are already taking another diabetes drug should follow their doctor's directions precisely. Patients should follow their medication treatment plan, meal plan, and exercise program as they transition to Janumet.

Patients should check their blood sugar regularly, track results, and share them with their doctor. Tell your doctor if your blood sugar measurements are too high or too low, your dosage may need to be adjusted.

Considerations Before Taking Janumet

Before starting treatment, discuss the possibility of allergic reactions to Janumet or its ingredients.

It is vital to discuss your medical history, especially relating to kidney disease, liver disease, gallstones, and pancreatitis. Your treating physician should be informed about any severe breathing problems (e.g. obstructive lung disease, asthma) and blood problems (e.g. anemia, vitamin B12 deficiency).

Before surgery or scanning procedures that use iodinated contrast, patients should inform their doctor or dentist about all prescriptions, non-prescription drugs, and herbal products that they take. Patients may need to stop taking Janumet shortly before certain medical procedures.

Some patients may experience extremely low or high blood sugar levels, causing symptoms like blurred vision, dizziness, or drowsiness. Do not drive, use machinery, or perform activities which require alertness until you are in condition to perform them safely. Limit alcohol consumption, as it increases the risk of lactic acidosis.

Severe dehydration is another risk factor associated with lactic acidosis. High fever, excessive sweating, diarrhea, and vomiting all contribute to dehydration, as can diuretic use.

Patients who have prolonged diarrhea or vomiting should stop taking Janumet and immediately inform their doctor. Patients should drink large amounts of fluids to prevent dehydration unless told otherwise by their doctor.

When experiencing physical stress (e.g. fever, infection, injury, or surgery), you may find it harder to control blood sugar levels. Your doctor may recommend a change in your treatment plan, medication, or blood sugar testing methods.

Older adults may be at greater risk for negative side effects of Janumet, especially lactic acidosis.

During pregnancy, Janumet must only be used when clearly needed. Women should discuss the risks and benefits with their doctor. Some women may be directed to use insulin instead of Janumet during pregnancy.

Metformin can cause changes in the menstrual cycle, promoting ovulation and increasing the risk of pregnancy. Women should discuss the use of reliable forms of birth control with their doctor or pharmacist.

Small amounts of metformin – one of the two active ingredients in Janumet – are known to pass into breast milk. It is unknown if the other active ingredient – sitagliptin – passes into breast milk. Consult your doctor before breastfeeding

Delayed and Omitted Doses

Patients who miss a dose of Janumet should take it as soon as they remember. If this happens near the time for the next dose, patients should skip the missed dose and proceed as usual. Patients should not double their dose to catch up.

Other Medications and Janumet

Drug interactions may change the way Janumet works, increasing the risk of side effects. Before starting treatment, patients need to discuss the full list of medications and supplements they are taking with their doctor. Patients should not change their dose or stop taking Janumet unless their physician directs them to do so.

Some beta blocker medications may prevent patients from experiencing telltale symptoms of low blood sugar like fast or pounding heartbeat. Symptoms like dizziness, hunger, and sweating are unaffected by these medications. Examples of beta blocker medications include the blood pressure drugs metoprolol and propranolol, as well as glaucoma eye drops like timolol.

Many drugs have the potential to affect blood sugar levels. Before starting any new treatment or changing your existing medication, discuss possible side effects with your doctor or pharmacist. It is important to check blood sugar levels regularly and share results with your treating physician.

This document does not contain a full list of all possible interactions. Please consult your physician before buying Janumet online.

Adverse Reactions

Most patients are able to take Janumet safely without serious side effects.

Some patients may experience nausea, vomiting, stomach upset, diarrhea, and a metallic taste in the mouth. A headache and weakness are also possible. Patients should alert their doctor if these symptoms persist.

Stomach symptoms that return after taking Janumet for several days or weeks may be a sign of lactic acidosis. Report such symptoms to your doctor immediately.

Janumet does not normally cause low blood sugar (hypoglycemia). Hypoglycemia, however, may occur if Janumet is prescribed and taken with other diabetes medications.

Hypoglycemic side effects can include: sudden sweating, shaking, fast heartbeat, hunger, blurred vision, dizziness, and tingling hands and/or feet. Patients should carry glucose tablets or gel in the event of hypoglycemic symptoms, though consuming table sugar, honey, candy, non-diet soda, or fruit juice can rapidly raise blood sugar. Inform your doctor of the incident immediately.

Low blood sugar is more likely to occur if patients drink large amounts of alcohol, do unusually heavy exercise, or fail to consume enough calories from food. Eating meals on a regular schedule helps to keep blood sugar levels steady. Avoid skipping meals.

High blood sugar (hyperglycemia) can manifest in symptoms like thirst, increased urination, confusion, drowsiness, flushing, rapid breathing, and fruity breath odor. If these symptoms occur, tell your doctor right away. You may need to have your diabetes medication adjusted.

Serious side effects can include joint pain, unusual skin blisters, and signs of kidney problems (e.g. changes in urine production). Patients should also monitor for symptoms of heart failure: shortness of breath, unusual tiredness, unusual or sudden weight gain, and swelling of the ankles and/or feet.

Patients should seek immediate medical help in the event of pancreatitis symptoms like persistent nausea, vomiting, loss of appetite, severe stomach pain, and severe back pain. Seek urgent help in the event of lactic acidosis. Symptoms of lactic acidosis are already described in the Warning section.

Serious allergic reactions to Janumet are rare, yet patients should be aware of allergy symptoms such as rash, itching and swelling (tongue/throat), severe dizziness, and trouble breathing.

This is not a complete list of possible side effects. For a full list, consult your physician or pharmacist.

How to Store Janumet

Janumet should be stored at room temperature, away from light and moisture. Do not store in the bathroom. Keep away from children and pets.

Unwanted medication should be disposed of properly and should not be poured down drains or flushed down the toilet. Patients should consult a pharmacist or their local waste disposal company to find out more about safe disposal methods.

Janumet Coupon

Although Janumet coupons are available with other online pharmacies, customers will find that UDS prices are often much lower.

IMPORTANT DISCLAIMER: All medical content is supplied by a third-party company who is independent from this web site. As such, this web site cannot guarantee the reliability, accuracy, and /or medical efficacy of the information provided. In all circumstances, you should seek the advice of a health professional pertaining to drug, treatment and/or medical condition advice. Note that not all products are shipped by our contracted Canadian pharmacy. This website contracts with dispensaries around the world that ship products directly to our customers. Some of the jurisdiction include but are not limited to United Kingdom, Europe, Turkey, India, Canada, Vanuatu, Mauritius, and USA. The items within your order may be shipped from any one of these jurisdictions depending on the availability and cost of the products at the time you place your order. The products are sourced from these countries as well as others. Please note that the product appearance may vary from actual product received depending on availability.