What is a generic medication?
Generic medications are significantly discounted copies of brand name medication that have the same active ingredients, intended use, dosage, side effects, effects, and route of administration as the original brand name medication. In other words, generic medications have the same pharmacological effects as their brand-name counterparts. Over half of all prescribed medications are for generic medications.
Prandimet Drug Information
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This diabetes medication is a combination of 2 drugs (repaglinide and metformin). Prandimet is used along with a diet and exercise program to control high blood sugar in patients with type 2 diabetes. Repaglinide works by stimulating the release of your body's natural insulin. Metformin is a biguanide and works by decreasing the amount of sugar that your liver makes and that your stomach/intestines absorb. Both of these medications work by helping to restore your body's proper response to the insulin you naturally produce. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke.
Rarely, too much metformin can build up in the body and cause a serious (sometimes fatal) condition called lactic acidosis. Lactic acidosis is more likely if you are an older adult, if you have kidney or liver disease, dehydration, heart failure, heavy alcohol use, if you have surgery, if you have X-ray or scanning procedures that use iodinated contrast, or if you are using certain drugs. For some conditions, your doctor may tell you to stop taking Prandimet for a short time. Ask your doctor or pharmacist for more details. Stop taking Prandimet and get medical help right away if you have any symptoms of lactic acidosis, such as unusual tiredness, dizziness, severe drowsiness, chills, blue/cold skin, muscle pain, fast/difficult breathing, slow/irregular heartbeat, or stomach pain with nausea/vomiting/diarrhea.
How to Use Prandimet
Take Prandimet by mouth within 30 minutes before a meal as directed by your doctor, usually 2-3 times a day. Do not take a dose of medication if you are skipping a meal. Drink plenty of fluids while taking Prandimet unless otherwise directed by your doctor. The Dosage of Prandimet is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). To reduce your risk of side effects (such as upset stomach), your doctor may direct you to start Prandimet at a low dose and gradually increase your dose. Follow your doctor's instructions carefully. If you are changing from a different diabetes drug (such as chlorpropamide), follow your doctor's directions carefully for stopping the old drug and starting this combination medication. Use Prandimet regularly in order to get the most benefit from it. Carefully follow the medication treatment plan, meal plan, and exercise program your doctor has recommended. Check your blood sugar regularly as directed by your doctor. Keep track of the results and share them with your doctor. Tell your doctor if your blood sugar measurements are too high or too low. Your treatment plan may need to be changed.
Before taking Prandimet, tell your doctor or pharmacist if you are allergic to repaglinide or metformin; or if you have any other allergies. Prandimet may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using Prandimet, tell your doctor or pharmacist your medical history,kidney disease, breathing problems (such as obstructive lung disease, severe asthma), blood problems (such as anemia, vitamin B12 deficiency), heart problems (such as heart failure, recent heart attack), liver disease, recent stroke. Before having surgery or any X-ray/scanning procedure using iodinated contrast, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). You may need to stop Prandimet for a short time for the surgery/procedure. Ask your doctor or dentist for instructions before your surgery/procedure. You may experience blurred vision, dizziness, or drowsiness due to extremely low or high blood sugar. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Limit alcohol while taking Prandimet because it can increase the risk of developing hypoglycemia and lactic acidosis. Consult your doctor or pharmacist about using alcohol safely. It may be harder to control your blood sugar when your body is stressed (such as fever, infection, injury, or surgery). Tell your doctor if you get a serious infection or injury. Your doctor may need to adjust your diabetes medication, exercise program, or diet. Older adults may be at greater risk for side effects such as low blood sugar or lactic acidosis. Prandimet can cause changes in the menstrual cycle and make it easier to become pregnant. If you do not want to become pregnant, consult your doctor or pharmacist about using reliable birth control. During pregnancy, Prandimet should be used only when clearly needed. Insulin treatment may be preferred during pregnancy. Discuss the risks and benefits with your doctor. Follow your doctor's instructions carefully. Prandimet passes into breast milk and may have undesirable effects on a nursing infant. Breast-feeding while using Prandimet is not recommended. Consult your doctor before breast-feeding.
If you miss a dose of Prandimet, skip that dose. Take your next dose with your next meal. Do not double the dose to catch up.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.NPH insulin. Other medications can affect the removal of repaglinide from your body, which may affect how repaglinide works. Examples include clopidogrel, gemfibrozil, trimethoprim, azole antifungals (such as itraconazole, ketoconazole), macrolide antibiotics (such as erythromycin), rifamycins (such as rifabutin), St. John's wort, among others. Other drugs can affect the kidneys. This effect may slow down the removal of metformin from the body. Metformin may also slow down the removal of other drugs. Examples of affected drugs include some antibiotics (such as cephalexin, penicillin) and probenecid. Many drugs can affect your blood sugar, making it harder to control. Before you start, stop, or change any medication, talk with your doctor or pharmacist about how the medication may affect your blood sugar. Check your blood sugar regularly as directed and share the results with your doctor. Tell your doctor right away if you have symptoms of high or low blood sugar. (See also Side Effects section.) Your doctor may need to adjust your diabetes medication, exercise program, or diet. Beta-blocker medications (such as metoprolol, propranolol, glaucoma eye drops such as timolol) may prevent the fast/pounding heartbeat you would usually feel when your blood sugar falls too low (hypoglycemia). Other symptoms of low blood sugar such as dizziness, hunger, or sweating are unaffected by these drugs. Check the labels on all your medicines (such as cough-and-cold products) carefully. Some products may contain sugar or alcohol and may affect your blood sugar. Ask your doctor or pharmacist about using these products safely. Other medications can affect the results of urine tests for sugar or ketones. Consult your doctor or pharmacist for more information.
Prandimet Side Effects
Nausea, diarrhea, and upset stomach may occur as your body adjusts to the metformin. Weight gain and joint pain may also occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. If stomach symptoms return later (after you are on the same dose for several days or weeks), tell your doctor right away. Stomach symptoms that occur after the first days of your treatment may be a sign of lactic acidosis. Remember that Prandimet has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using Prandimet do not have serious side effects. Prandimet may cause low blood sugar (hypoglycemia), especially if you drink large amounts of alcohol, do unusually heavy exercise, or do not consume enough calories from food. Symptoms include cold sweat, blurred vision, dizziness, drowsiness, shaking, fast heartbeat, headache, fainting, tingling of the hands/feet, and hunger. It is a good habit to carry glucose tablets or gel to treat low blood sugar. If you don't have these reliable forms of glucose, rapidly raise your blood sugar by eating a quick source of sugar such as table sugar, honey, or candy, or drink fruit juice or non-diet soda. Tell your doctor about the reaction right away. To help prevent low blood sugar, eat meals on a regular schedule, and do not skip meals. Check with your doctor or pharmacist to find out what you should do if you miss a meal. Symptoms of high blood sugar (hyperglycemia) include thirst, increased urination, confusion, drowsiness, flushing, rapid breathing, and fruity breath odor. If these symptoms occur, tell your doctor right away. Your dosage may need to be increased. A very serious allergic reaction to Prandimet is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction,rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard Prandimet when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
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