Rythmol

(Propafenone Hydrochloride)

Rythmol SR (propafenone HCl) is a Class IC antiarrhythmic agent used to treat certain abnormal heart rhythm problems such as atrial fibrillation (AFib), atrial flutter, ventricular arrhythmias, and paroxysmal supraventricular tachycardia (PSVT). For those with structural heart disease, such as problems with the heart valves, it can be life-threatening. Either immediate-release (IR) tablets or extended-release (ER) capsules of propafenone are taken orally, usually two to three times a day.

Propafenone doesn't belong to the class of medications called beta blockers but can cause similar side effects as beta-blockers, such as slowing your heart rate.

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Brand Versions

Rythmol Prescription Required

Strength
150mg
Country
United Kingdom
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Marketed as Arythmol in United Kingdom

Rythmol Prescription Required

Strength
300mg
Country
United Kingdom
Select Quantity

Marketed as Arythmol in United Kingdom

Generic Versions
What are generics?

Propafenone Hydrochloride Prescription Required

Strength
150mg
Country
United States
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Propafenone Hydrochloride Prescription Required

Strength
225mg
Country
United States
Select Quantity

Propafenone Hydrochloride Prescription Required

Strength
300mg
Country
United States
Select Quantity
Also available from United Kingdom
Strength
300mg
Country
United Kingdom
Select Quantity

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Important information about Rythmol

How does Rythmol work?

The active ingredient in Rythmol SR is propafenone hydrochloride, which is an antiarrhythmic. The mechanism of action involves obstructing sodium channels, which are crucial for the electrical activity of your heart. To treat irregular beats, it reduces the heart's abnormal electrical activity.

How do you use Rythmol?

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Rythmol SR. However, the following is a synopsis of the general guidelines for the use of Rythmol SR:

  • Rythmol SR can be taken with or without food.
  • When using this drug, your blood pressure may drop extremely low. If you have diarrhea or vomiting, excessive thirst, appetite loss, or excessive perspiration, call your doctor.
  • You could require blood tests regularly.
  • An electrocardiogram, or ECG, may also be required to assess your heart function both before and after Rythmol SR treatment in individuals with hepatic (liver) dysfunction, asthma, congestive heart failure, or bradycardia.

What are the side effects of Rythmol?

The most common side effects of Rythmol SR seen in clinical trials as compared to placebo include:

  • Dizziness.
  • Palpitations (fast or irregular heartbeats).
  • Shortness of breath.
  • Constipation.
  • Blurred vision.
  • Low white blood cell levels (agranulocytosis).
  • Low blood pressure (hypotension).

Some individuals may experience serious side effects while using Rythmol SR. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

  • Chest pain (angina) or discomfort, weakness, lightheadedness, or fainting are signs of an irregular heartbeat.
  • Unexpected weight gain, fluid accumulation in the legs or feet, or increased shortness of breath, particularly when lying down, and sudden weight gain are signs of new or worsening heart failure.
  • Fever, chills, and sore throat are signs of infection.
  • Allergic reactions to the medication such as hives, swelling of the face, tongue, or throat, and trouble breathing.

These are not all of the possible adverse reactions of Rythmol SR. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

What are the warnings or precautions for Rythmol?

Before starting Rythmol SR, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including if you have:

  • Cardiac failure, or if a heart attack has recently occurred.
  • Brugada syndrome, an inherited cardiac disease.
  • A severe cardiac ailment like "AV block" or "sick sinus syndrome" (unless you have a pacemaker).
  • Very low blood pressure or a history of fainting due to sluggish heartbeats.
  • An electrolyte imbalance that is severe or out of control.
  • Shortness of breath or wheezing.
  • Kidney or liver disease.
  • Lupus.
  • Myasthenia gravis.
  • A defibrillator or pacemaker.

Are there any contraindications with Rythmol?

  • Heart failure.
  • Cardiogenic shock.
  • Issues with the heart's electrical activity when a pacemaker is not present.
  • Brugada syndrome.
  • Slow heart rate.
  • Severely low blood pressure.
  • Diseases of the lungs that impair breathing, such as COPD, or chronic Obstructive pulmonary disease.
  • Levels of electrolytes that are not balanced.

How long does it take Rythmol to work?

Rythmol SR typically takes 10 to 50 hours to leave your system, according to its half-life. However, some people's genetic makeup causes them to break down the medicine more slowly. It may take up to a week for your body to process the drug if you fall into this category.

What interacts with Rythmol?

When Rythmol SR is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the incidence or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

  • Digoxin.
  • Warfarin.
  • Amiodarone.
  • Ketoconazole.
  • Flecainide.
  • Cimetidine.
  • Erythromycin.
  • Fluoxetine.
  • Quinidine.
  • Rifampin.
  • Ritonavir.
  • Orlistat.
  • Grapefruit juice.

What doses of Rythmol are available?

Propafenone is available in immediate- and extended-release dosage forms.

For immediate-release tablets, 150 mg taken orally every eight hours is the usual starting dose. If necessary, your doctor will gradually change your dosage. 300 mg per eight hours is the maximum dosage.

The usual starting dosage for extended-release capsules (Rythmol SR) is 225 mg taken orally every 12 hours. If necessary, your doctor will gradually change your dosage. 425 mg per 12 hours is the maximum dosage.

How do I store Rythmol?

Store your medication Rythmol SR at room temperature and out of reach of children.

Which pharmaceutical company manufactures Rythmol?

GlaxoSmithKline is the pharmaceutical company that manufactures Rythmol SR.

Is there a generic version of Rythmol?

There are several lower-cost generic versions of Rythmol SR.

How do I stop taking Rythmol?

Consult your doctor before ceasing to use this medication. If you abruptly stop using propafenone, your condition may worsen.

Can Rythmol be used if I am pregnant?

Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.

Can Rythmol be used if I am breast feeding?

Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.

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Important information about buying Rythmol from UniversalDrugstore™

What happens after I place my order for Rythmol with Universal Drugstore?

Once you complete your order, we process, verify, and dispatch your medication. You’ll receive email updates at each stage, including tracking details once your order ships. If any additional documentation is needed (such as a valid prescription), we’ll contact you promptly. Once approved, your order is charged and delivered directly to your doorstep.

How long does it take to process and deliver my order for Rythmol?

Orders are typically processed within 1–3 business days once all required documents are received and approved. Standard delivery times range from 10–18 business days, depending on your location.

Can I track my order of Rythmol?

Yes! Once your medication ships, you will receive an email with tracking information so you can monitor your shipment every step of the way.

What should I do if there is an issue with my order for Rythmol?

Our Customer Care team is available 24/7 to assist with any order-related concerns or questions. If you experience delays, missing items, or need support, contact us using the details provided in your confirmation email.

How is my medication packaged to ensure privacy and safety?

All orders are shipped in discreet, plain packaging to protect your privacy. Medications are securely packaged to prevent damage and ensure they arrive in top condition.

Does Universal Drugstore ship medications that require refrigeration or special handling?

Yes. We use cold-chain shipping methods to safely transport temperature-sensitive medications, ensuring they maintain proper storage conditions throughout delivery.

What are the shipping costs, and does Universal Drugstore offer free delivery?

Shipping costs vary depending on your location and shipping method. Free shipping promotions may be available—check the checkout page for the latest offers. Orders above $100 going to a US destination will receive free shipping.

Does Universal Drugstore accept Medicare or Medicaid for prescriptions?

Currently, we do not bill Medicare or Medicaid directly. However, we provide detailed receipts and documentation that you can submit to your insurance provider for potential reimbursement.

Can I use private health insurance to cover my prescription from Universal Drugstore?

Universal Drugstore does not bill private health insurance directly, but we provide a detailed invoice that you can submit to your insurer for possible reimbursement. Many insurers will accept Unievrsal Drugstore’s documents, but if you have any questions, check with your insurance company prior to purchasing.

How secure is my payment information when ordering from Universal Drugstore?

We use advanced SSL encryption and secure payment processing to ensure that all transactions are 100% protected against fraud and unauthorized access.

Can I order a generic alternative to Rythmol?

Universal Drugstore offers many generic alternatives that provide the same active ingredients at a lower cost. Search for your medication and compare pricing for generic vs. brand-name options. Generic availability depends on the medication.

Do I need a prescription to order Rythmol?

If your medication requires a prescription, you must upload it online, via email, or fax. Over-the-counter (OTC) medications do not require a prescription. All prescription medication purchases require a valid and approved prescription.

Can I order multiple medications at once?

Yes! You can add multiple medications to your cart, including prescription, OTC, and pet medications, and complete your purchase in a single checkout process.

Can I refill my prescription through Universal Drugstore?

Yes! If your prescription includes refills, you can reorder quickly by logging into your account and selecting your medication for a hassle-free refill process. Always refill your medication proactively and ontime, to ensure you do not run out of important medication.

Does Universal Drugstore offer discounts or price matching?

Yes! We offer:

  • Up to 80% savings on medications
  • Price match guarantee – we’ll match competitor pricing on qualifying medications
  • 10% off your first order for new customers

How can I contact Universal Drugstore for additional support?

We offer 24/7 customer support via phone, email, and chat. Visit our Contact Us page for assistance with ordering, shipping, or medication questions.

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Important

The information, including but not limited to, text, graphics, images and other material contained on this website are for informational purposes to increase health awareness only. No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. 



Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website.