Buy Symmetrel Online (Amantadine Hydrochloride)
What is Symmetrel?
What is Symmetrel?
Symmetrel is a brand-name, medication that contains amantadine hydrochloride. It is used to treat symptoms of Parkinson’s disease and drug-induced movement disorders. It may also be used as an antiviral for the prevention and treatment of influenza A virus infections, although this use is less common today due to resistance.
Symmetrel works on the nervous system to help improve muscle control, reduce stiffness, and decrease tremors associated with Parkinson’s disease. It may also be used alongside other treatments such as levodopa to improve symptom control.
This medication is available in oral forms, including capsules and liquid, and should only be used under the guidance of a healthcare provider.
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Symmetrel brand
Symmetrel 100mg
Prescription RequiredProduct of Australia
Amantadine (generic Symmetrel)
Amantadine Hydrochloride 100mg
Prescription RequiredProduct of India
Marketed as Parkitidin in India.
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Marketed as Amantadine Hydrochloride in United Kingdom
Amantadine Hydrochloride (generic Symmetrel)
Amantadine Hydrochloride 100mg
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Marketed as PDP-Amantadine in Canada.
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Important information about Symmetrel
The active ingredient in Symmetrel is amantadine hydrochloride.
Amantadine works through multiple mechanisms of action in the central nervous system. It helps increase dopamine release and block its reuptake, which improves communication between nerve cells and helps reduce symptoms of Parkinson’s disease such as stiffness and slowed movement. It also has mild anticholinergic effects that support movement control. For antiviral activity, amantadine interferes with the replication of the influenza A virus by blocking viral uncoating inside cells.
Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Symmetrel. However, the following is a synopsis of the general guidelines for the use of Symmetrel:
- Take Symmetrel exactly as prescribed by your healthcare provider.
- It is taken by mouth, with or without food.
- Try to take doses at the same time each day.
- Do not take extra doses or skip doses without medical advice.
- If you miss a dose, take the next dose at your regular time and do not double up.
- Dose adjustments may be needed in elderly patients or those with kidney disease.
- Do not stop the medication suddenly, as this may worsen symptoms or lead to complications such as neuroleptic malignant syndrome (nms).
Some mild or common side effects of Symmetrel seen in clinical trials as compared to placebo include:
- Dry mouth.
- Constipation.
- Lightheadedness or dizziness.
- Blurred vision.
- Nausea.
- Trouble sleeping.
Some individuals may experience serious side effects while using Symmetrel. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:
- Suicidal thoughts or changes in mood or behavior.
- Severe confusion or hallucinations.
- Signs of heart failure such as swelling or shortness of breath.
- Severe low blood pressure or orthostatic hypotension.
- Allergic reaction including hives or skin rash.
- Neuroleptic malignant syndrome symptoms such as fever, muscle stiffness, and altered mental status.
These are not all of the possible side effects of Symmetrel. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.
Before starting Symmetrel, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including if you have:
- Kidney disease or reduced renal function.
- Glaucoma.
- Heart failure or other heart conditions.
- A history of seizures or neurological disorders.
- Mental health conditions such as depression or psychosis.
Additional precautions:
- Use caution in elderly patients, as they may be more sensitive to side effects.
- Avoid drinking alcohol, as it may worsen dizziness or nervous system effects.
- Monitor for unusual behavioral changes or mood swings.
- Adjust dosing in patients with renal impairment to prevent toxicity.
Known hypersensitivity to amantadine or any component of the formulation.
Use caution in patients with severe kidney disease or conditions affecting drug clearance.
Some improvement in symptoms of Parkinson’s disease may be noticed within a few days to a week after starting treatment. However, full effects may take several weeks depending on the condition being treated.
When Symmetrel is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:
- Triamterene and hydrochlorothiazide, which may reduce clearance of amantadine and increase toxicity.
- Quinidine, which may increase amantadine levels in the body.
- Anticholinergic medications, which may increase side effects such as dry mouth and blurred vision.
- Levodopa, which may enhance therapeutic effects but also increase side effects like dyskinesia.
Symmetrel is available in the following dosage forms:
- Oral capsules.
- Oral liquid (amantadine hydrochloride solution).
Typical dosing:
Adults: Usually 100 mg once or twice daily.
For Parkinson’s disease, doses may be increased gradually based on response.
Lower doses are recommended in elderly patients and those with kidney disease.
It should be stored at room temperature, away from the reach of children or pets.
Symmetrel is manufactured by Endo Pharmaceuticals.
Yes, amantadine is available as a generic medication.
Do not stop taking Symmetrel suddenly without speaking to your healthcare provider.
Gradual dose reduction may be needed to avoid withdrawal effects.
Sudden discontinuation may worsen Parkinson’s disease symptoms or cause serious reactions.
Always follow medical advice when stopping treatment.
Amantadine should only be used during pregnancy if clearly needed, as it may pose risks to the unborn baby.
Amantadine passes into breast milk and may affect the infant, so caution is advised.
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Click to joinImportant information about buying Symmetrel from UniversalDrugstore™
We ship to destinations within the United States, including Alaska and Hawaii, as well as internationally. Delivery typically takes about 2 weeks for orders shipped within the U.S. and Canada, and about 4 weeks for international orders, depending on your location and customs processing.
Once you complete your order, we process, verify, and dispatch your medication. You’ll receive email updates at each stage, including tracking details once your order ships. If any additional documentation is needed (such as a valid prescription), we’ll contact you promptly. Once approved, your order is charged and delivered directly to your doorstep.
Orders are typically processed within 1–3 business days once all required documents are received and approved. Standard delivery times range from 10–18 business days, depending on your location.
Yes! Once your medication ships, you will receive an email with tracking information so you can monitor your shipment every step of the way.
Our Customer Care team is available 24/7 to assist with any order-related concerns or questions. If you experience delays, missing items, or need support, contact us using the details provided in your confirmation email.
All orders are shipped in discreet, plain packaging to protect your privacy. Medications are securely packaged to prevent damage and ensure they arrive in top condition.
Yes. We use cold-chain shipping methods to safely transport temperature-sensitive medications, ensuring they maintain proper storage conditions throughout delivery.
Shipping costs vary depending on your location and shipping method. Free shipping promotions may be available—check the checkout page for the latest offers. Orders above $100 going to a US destination will receive free shipping.
Currently, we do not bill Medicare or Medicaid directly. However, we provide detailed receipts and documentation that you can submit to your insurance provider for potential reimbursement.
Universal Drugstore does not bill private health insurance directly, but we provide a detailed invoice that you can submit to your insurer for possible reimbursement. Many insurers will accept Universal Drugstore’s documents, but if you have any questions, check with your insurance company prior to purchasing.
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Universal Drugstore offers many generic alternatives that provide the same active ingredients at a lower cost. Search for your medication and compare pricing for generic vs. brand-name options. Generic availability depends on the medication.
If your medication requires a prescription, you must upload it online, via email, or fax. Over-the-counter (OTC) medications do not require a prescription. All prescription medication purchases require a valid and approved prescription. The Universal Drugstore customer care team can contact your doctor directly to get your prescription, and ensure all information is up to date.
Yes! You can add multiple medications to your cart, including prescription, OTC, and pet medications, and complete your purchase in a single checkout process.
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Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website.

Jamie Winn, PharmD, is a licensed pharmacist and seasoned medical content reviewer with over 20 years of experience in clinical pharmacy, patient care, and healthcare leadership.
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Shirley is a Medical Writer and first-year Doctor of Pharmacy (PharmD) student at the University of Alberta, where she is building on her strong foundation in health sciences and patient care.
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