Zenpep (Lipase/Protease/Amylase)
Zenpep (lipase/protease/amylase) is a prescription medication used to treat exocrine pancreatic insufficiency, a condition where the lack of pancreatic enzyme production leads to digestive issues. Zenpep is safe and effective to use in both adults and children. It contains a mixture of digestive enzymes that help break down food making it easier to digest.
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Zenpep brand
Zenpep 10,000/32,000/42,000IU
Prescription RequiredLipase/Protease/Amylase (generic Zenpep)
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Important information about Zenpep
How does Zenpep work?
The active ingredients in Zenpep are three pancrelipases or pancreatic enzymes known as lipase, protease, and amylase. These three enzymes play an important role in ensuring our food is digested. However, people with pancreatic issues have a hard time producing these enzymes, thus making it difficult to digest their food, causing symptoms of abdominal pain or tenderness, loss of appetite, weight loss, and much more. These enzymes are derived from pig pancreases and then packaged into capsules that are to be taken daily with meals. Other pancreatic enzyme products on the market include Creon and Viokace, among others. Generally, you should not switch between products without consulting your doctor first.
How do you use Zenpep?
Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Zenpep. However, the following is a synopsis of the general guidelines for the use of Zenpep:
- Zenpep should be used exactly as prescribed. Do not take more Zenpep capsules in a day than what has been prescribed for you.
- The dose of Zenpep will vary from person to person based on your body weight, symptoms, and total fat intake. If you experience symptoms of abdominal pain, bloating, fatty stools, or weight loss, these could be signs that your dose needs to be adjusted as your body is not absorbing nutrients properly.
- Zenpep is typically taken daily with each meal or snack. However, if you have a lot of meals or snacks throughout the day, be careful not to go over your daily recommended dose.
- Take the capsules whole with a full glass of water or juice. Do not crush, chew, or hold the contents in your mouth, as doing so can irritate the tissue and lining of your mouth. For those who have trouble swallowing, capsules may be opened and the contents sprinkled on acidic, soft foods like applesauce, bananas, or pears and taken immediately for easier administration. Do not sprinkle on other foods without consulting your doctor first.
- For infants, Zenpep may be given in 2 ways:
--- Similar to adults, the capsule may be opened and contents sprinkled on a small amount of applesauce, bananas, or pears each time the baby breastfeeds or has formula. Once sprinkled on food, it must be given immediately. To minimize mouth irritation, proceed with breastfeeding or formula right away to help wash the contents of the capsule down. You can check your baby’s mouth to make sure it has all been swallowed. Do not mix Zenpep capsule contents into a bottle of breast milk or formula.
--- Alternatively, you may also open the capsule and sprinkle the contents directly into the baby’s mouth and immediately follow with breastfeeding or formula. Again, check the baby’s mouth to ensure all the medicine has been swallowed.
- If you miss a dose, skip the missed dose and wait until your next meal/snack to take your next dose (or for a baby, wait until the next feeding). If you are unsure how to proceed, call your doctor for further guidance.
What are the side effects of Zenpep?
The most common side effects of Zenpep seen in clinical trials as compared to placebo include:
- Headache
- Bruising
- Cough
- Feeling full after eating very little
Some individuals may experience serious side effects while using Zenpep. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:
- Mouth irritation, especially if the capsules are not swallowed completely.
- Hyperuricemia or high blood uric acid levels. Signs to watch for include pain, stiffness, or redness/swelling of your joints.
- Signs of fibrosing colonopathy such as stomach pain, bloating, constipation, nausea, vomiting, or diarrhea. This is a rare bowel disorder that is more common in children with cystic fibrosis who have been taking Zenep at high doses for a long time.
- Signs of a severe allergic reaction such as hives, rash, difficulty breathing, or swelling of the face, lips, eyes, or tongue.
These are not all of the possible side effects of Zenpep. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.
What are the warnings or precautions for Zenpep?
Before starting Zenpep, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including if you have:
- An allergy to porcine or pork products
- A history of fibrosing colonopathy (blockage of intestines or thickening/scarring of the bowel wall)
- Gout
- Kidney disease
- High levels of uric acid in your blood (hyperuricemia)
- Difficulties swallowing
- Are pregnant or plan to become pregnant
- Are breastfeeding or plan to breastfeed
Are there any contraindications with Zenpep?
There are no contraindications to using Zenpep.
How long does it take Zenpep to work?
Zenpep starts to work right after the first dose to help make it easier to digest your food.
What interacts with Zenpep?
When Zenpep is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions.
What doses of Zenpep are available?
Zenpep is available as delayed-release capsules that come in the following strengths:
- 3,000 USP units of lipase; 10,000 USP units of protease; and 14,000 USP units of amylase
- 5,000 USP units of lipase; 17,000 USP units of protease; and 24,000 USP units of amylase
- 10,000 USP units of lipase; 32,000 USP units of protease; and 42,000 USP units of amylase
- 15,000 USP units of lipase; 47,000 USP units of protease; and 63,000 USP units of amylase
- 20,000 USP units of lipase; 63,000 USP units of protease; and 84,000 USP units of amylase
- 25,000 USP units of lipase; 79,000 USP units of protease; and 105,000 USP units of amylase
- 40,000 USP units of lipase; 126,000 USP units of protease; and 168,000 USP units of amylase
- 60,000 USP units of lipase; 189,600 USP units of protease; and 252,600 USP units of amylase
How do I store Zenpep?
Zenpep should be stored in its original container at room temperature. Protect from heat, light, and moisture. Keep the bottle tightly closed after opening. Keep out of reach of children.
Which pharmaceutical company manufactures Zenpep?
Zenpep is manufactured by the pharmaceutical company Aimmune Therapeutics, Inc.
Is there a generic version of Zenpep?
Currently, there is no generic of the brand name Zenpep.
How do I stop taking Zenpep?
Consult your doctor or pharmacist before starting, stopping, or changing medications while taking Zenpep.
Can Zenpep be used if I am pregnant?
Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.
Can Zenpep be used if I am breast feeding?
It is unknown whether Zenpep passes into the breast milk. Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.
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What happens after I place my order for Zenpep with Universal Drugstore?
Once you complete your order, we process, verify, and dispatch your medication. You’ll receive email updates at each stage, including tracking details once your order ships. If any additional documentation is needed (such as a valid prescription), we’ll contact you promptly. Once approved, your order is charged and delivered directly to your doorstep.
How long does it take to process and deliver my order for Zenpep?
Orders are typically processed within 1–3 business days once all required documents are received and approved. Standard delivery times range from 10–18 business days, depending on your location.
Can I track my order of Zenpep?
Yes! Once your medication ships, you will receive an email with tracking information so you can monitor your shipment every step of the way.
What should I do if there is an issue with my order for Zenpep?
Our Customer Care team is available 24/7 to assist with any order-related concerns or questions. If you experience delays, missing items, or need support, contact us using the details provided in your confirmation email.
How is my medication packaged to ensure privacy and safety?
All orders are shipped in discreet, plain packaging to protect your privacy. Medications are securely packaged to prevent damage and ensure they arrive in top condition.
Does Universal Drugstore ship medications that require refrigeration or special handling?
Yes. We use cold-chain shipping methods to safely transport temperature-sensitive medications, ensuring they maintain proper storage conditions throughout delivery.
What are the shipping costs, and does Universal Drugstore offer free delivery?
Shipping costs vary depending on your location and shipping method. Free shipping promotions may be available—check the checkout page for the latest offers. Orders above $100 going to a US destination will receive free shipping.
Does Universal Drugstore accept Medicare or Medicaid for prescriptions?
Currently, we do not bill Medicare or Medicaid directly. However, we provide detailed receipts and documentation that you can submit to your insurance provider for potential reimbursement.
Can I use private health insurance to cover my prescription from Universal Drugstore?
Universal Drugstore does not bill private health insurance directly, but we provide a detailed invoice that you can submit to your insurer for possible reimbursement. Many insurers will accept Universal Drugstore’s documents, but if you have any questions, check with your insurance company prior to purchasing.
How secure is my payment information when ordering from Universal Drugstore?
We use advanced SSL encryption and secure payment processing to ensure that all transactions are 100% protected against fraud and unauthorized access.
Can I order a generic alternative to Zenpep?
Universal Drugstore offers many generic alternatives that provide the same active ingredients at a lower cost. Search for your medication and compare pricing for generic vs. brand-name options. Generic availability depends on the medication.
Do I need a prescription to order Zenpep?
If your medication requires a prescription, you must upload it online, via email, or fax. Over-the-counter (OTC) medications do not require a prescription. All prescription medication purchases require a valid and approved prescription. The Universal Drugstore customer care team can contact your doctor directly to get your prescription, and ensure all information is up to date.
Can I order multiple medications at once?
Yes! You can add multiple medications to your cart, including prescription, OTC, and pet medications, and complete your purchase in a single checkout process.
Can I refill my prescription through Universal Drugstore?
Yes! If your prescription includes refills, you can reorder quickly by logging into your account and selecting your medication for a hassle-free refill process. Always refill your medication proactively and ontime, to ensure you do not run out of important medication.
Does Universal Drugstore offer discounts or price matching?
Yes! We offer:
- Up to 80% savings on medications
- Price match guarantee – we’ll match competitor pricing on qualifying medications
- 10% off your first order for new customers
How can I contact Universal Drugstore for additional support?
We offer 24/7 customer support via phone, email, and chat. Visit our Contact Us page for assistance with ordering, shipping, or medication questions.
Important
The information, including but not limited to, text, graphics, images and other material contained on this website are for informational purposes to increase health awareness only. No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment.
Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website.