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Zortress Drug Information
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How Long Does It Take to Receive My Zortress Order?
You can easily place an order on our website in under 5 minutes. First you need to set up an account with us, create a payment method, and send us your prescriptions. Alternatively, you can order by downloading our order form or by placing an order over the phone. Delivery can take approximately 2 weeks to North America, and 4 weeks to other countries.
Everolimus is used with other medications (such as cyclosporine) to prevent rejection of a kidney transplant. Everolimus is also used with other medications (such as tacrolimus) to prevent rejection of a liver transplant. Zortress belongs to a class of drugs known as immunosuppressants. It works by weakening your body's defense system (immune system) to help your body accept the new organ as if it were your own.
Everolimus can increase your risk for developing certain types of cancers (including skin cancer, lymphoma). Tell your doctor right away if you notice unusual skin changes, change in the appearance/size of moles, unusual growths/lumps, swollen glands, night sweats, or loss of appetite/weight loss. Zortress lowers your ability to fight infections. This may make you more likely to get a serious (rarely fatal) infection or make any infection you have worse. Tell your doctor right away if you have any signs of infection (such as fever, chills, persistent sore throat, cough). Using Zortress may increase your risk for developing a blood clot in your kidney transplant, usually within the first 30 days after surgery. Tell your doctor right away if you have nausea/vomiting, pain in your groin/lower back/abdomen, blood in your urine, or unusual decrease in the amount of urine. Zortress may increase the risk of death from infection in people who have had a heart transplant. Before using Zortress, tell your doctor if you have had a heart transplant.
How to Use Zortress
Read the Medication Guide provided by your pharmacist before you start taking everolimus and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take Zortress by mouth as directed by your doctor, usually every 12 hours with your cyclosporine dose, beginning immediately after a kidney transplant. Everolimus is usually started 30 days after a liver transplant and is usually taken every 12 hours with your tacrolimus dose. You may take Zortress with or without food, but it is important to choose one way and take Zortress the same way with every dose. Swallow Zortress whole with a glass of water. Do not crush, chew, or break the tablets. The Dosage of Zortress is based on your medical condition, response to treatment, laboratory tests, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Use Zortress regularly to get the most benefit from it. To help you remember, take it at the same times each day. Do not increase your dose or use Zortress more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase. Avoid eating grapefruit or drinking grapefruit juice while using Zortress unless your doctor or pharmacist says you may do so safely. Grapefruit can increase the chance of side effects with this medicine. Ask your doctor or pharmacist for more details. Since Zortress can be absorbed through the skin and lungs and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle Zortress or breathe the dust from the tablets.
Before taking everolimus, tell your doctor or pharmacist if you are allergic to it; or to sirolimus or temsirolimus; or if you have any other allergies. Zortress may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using Zortress, tell your doctor or pharmacist your medical history,high cholesterol/triglyceride levels, any recent/current infections, diabetes, liver disease, certain hereditary enzyme problems (galactose intolerance, Lapp lactase deficiency, glucose-galactose malabsorption). Everolimus can make you more likely to get infections or may worsen any current infections. Therefore, wash your hands well to prevent the spread of infection. Avoid contact with people who have infections that may spread to others (such as chickenpox, measles, flu). Consult your doctor if you have been exposed to an infection or for more details. Do not have immunizations/vaccinations without the consent of your doctor. Avoid contact with people who have recently received live vaccines (such as flu vaccine inhaled through the nose). To lower the chance of getting cut, bruised, or injured, use caution with sharp objects like razors and nail cutters, and avoid activities such as contact sports. Since Zortress may increase your risk of developing skin cancer, limit your time in the sun. Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Tell your doctor if you are pregnant or plan to become pregnant. You should not become pregnant while using everolimus. Everolimus may harm an unborn baby. Female patients should ask about reliable forms of birth control while using Zortress and for 8 weeks after stopping treatment. Male patients with female partners should ask about reliable forms of birth control while using Zortress and for 4 weeks after stopping treatment. If you or your partner become pregnant, talk to your doctor right away about the risks and benefits of Zortress. Since Zortress can be absorbed through the skin and lungs and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle Zortress or breathe the dust from the tablets. It is unknown if Zortress passes into breast milk. Because of the possible risk to the infant, breast-feeding while using Zortress and for 2 weeks after stopping treatment is not recommended. Consult your doctor before breast-feeding.
If you miss a dose of Zortress, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.
See also How to Use section. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.other drugs that weaken the immune system/increase the risk of infection (such as natalizumab, rituximab), ACE inhibitors (such as captopril, lisinopril). Other medications can affect the removal of everolimus from your body, which may affect how everolimus works. Examples include azole antifungals (such as itraconazole, ketoconazole), cobicistat, macrolide antibiotics (such as clarithromycin, erythromycin), HIV and HCV protease inhibitors (such as atazanavir, boceprevir, ritonavir, telaprevir), rifamycins (such as rifabutin, rifampin), St. John's wort, telithromycin, among others.
Zortress Side Effects
What are Zortress side effects?
Side effects are physical, mental or emotional symptoms which occur in addition to or outside of the desired effect of a therapeutic treatment such as an over-the-counter or prescribed drug or medication. Side effects from Zortress may occur at the beginning or at the end of treatment and may also depend on the length of time an individual remains on the treatment. Side effects, also known as adverse effects, are generally more likely to occur when starting treatment. Individuals may also experience side effects from Zortress as a result of an interaction with other medications.
Side Effects of Zortress
The side effects of Zortress may vary in number and intensity for many different reasons. Factors such as age, weight, gender and ethnicity may influence the side effects of Zortress. Also, an individual’s state of general physical health and seriousness of the disease or illness as well as an increase or decrease in dosage may lead to side effects. Further, side effects from Zortress may also occur as a result of an interaction with certain herbal supplements, foods or drinks.
Prescription drug side effects can be serious and may cause patients to stop the treatment. However, when side effects from the use of a prescription drug, such as Zortress, do occur a patient should consult their physician. A physician may prescribe an additional treatment in order to control the symptoms or an adjustment in the dosage may be made. In addition, changes to diet, exercise or other lifestyle activities may help to lessen the side effects of Zortress.
By understanding side effects and the factors which may influence the occurrence of side effects patients are empowered to take an active role in their care. Patients who have specific questions about the side effects of Zortress, or any other medication, should contact their physician. General information about Zortress and the side effects associated with Zortress are described in the following:
Common Zortress Side Effects
- thrombocytopenic disorder
- headache disorder
- dry skin
- sore throat
- pruritus of skin
- general weakness
- skin rash
- peripheral edema
- acute bacterial otitis media
- upper respiratory infection
- acne vulgaris
- aphthous stomatitis
- symptoms of anxiety
- urinary tract infection
Less Frequent Zortress Side Effects
- neutropenic disorder
- pleural effusions
- palmar-plantar erythrodysesthesia
- chronic heart failure
- deep venous thrombosis
- kidney disease with reduction in GFR
- viral infection
- pericardial effusion
- eyelid edema
- chest pain
- follicle-stimulating hormone hypersecretion
- weight loss
- nail disorders
- aggressive behavior
- ovarian cyst
- acute abdominal pain
- jaw pain
- back pain
- blurred vision
- abdominal distension
- herpes simplex infection
- oral candidiasis
- tinea pedis
- body fluid retention
- vitamin B12 deficiency
- night sweats
- erectile dysfunction
- spasm of bladder
Rare or Very Rare Zortress Side Effects
- interstitial lung disease
- progressive multifocal leukoencephalopathy
- bacterial sepsis
- diabetes mellitus
- acute renal failure
- fungal sepsis
- post kidney transplant renal thrombosis
- malignant lymphoma
- malignant neoplasm of skin
- protozoal infection
- impaired wound healing
- pulmonary thromboembolism
- BK polyomavirus reactivation nephropathy
- hepatic artery thrombosis in liver transplant
- exfoliative dermatitis
- biliary calculus
- acute arterial thromboembolism
- Pneumocystis jirovecii pneumonia
- interstitial pneumonitis
- atrial fibrillation
- hypertensive crisis
- bloody vomit
- abnormal hepatic function tests
- male infertility
- hypersensitivity angiitis
- thrombotic thrombocytopenic purpura
- hemolytic uremic syndrome
- gastroesophageal reflux disease
- gingival hyperplasia
Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard Zortress when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
IMPORTANT DISCLAIMER: All medical content is supplied by a third party company who is independent from this web site. As such, this web site can not guarantee the reliability, accuracy, and /or medical efficacy of the information provided. In all circumstances, you should seek the advice of a health professional pertaining to drug, treatment and/or medical condition advice. Note that not all products are shipped by our contracted Canadian pharmacy. This website contracts with dispensaries around the world that ship products directly to our customers. Some of the jurisdiction include but are not limited to United Kingdom, Europe, Turkey, India, Canada, Vanuatu, Mauritius, and USA. The items within your order may be shipped from any one of these jurisdiction depending on the availability and cost of the products at the time you place your order. The products are sourced from these countries as well as others. Please note that the product appearance may vary from actual product received depending on availability.