Zyloprim

The active ingredient in Zyloprim is allopurinol, which is a xanthine oxidase inhibitor. It functions by preventing xanthine oxidase, an enzyme (protein), from producing uric acid. High levels of uric acid may cause gout attacks or kidney stones.

The medication helps reduce the joint pain and damage associated with gout by maintaining low uric acid levels. Lowering uric acid levels also helps avoid kidney stones and the side effects of some chemotherapy treatments that cause tumor lysis syndrome.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Zyloprim. However, the following is a synopsis of the general guidelines for the use of Zyloprim:

• To prevent stomach discomfort, you can take this medication after meals.
• To help prevent kidney stones, take this medication with lots of liquids. Consult your physician about the recommended daily intake of liquids. Additionally, you should consume more fiber.
• If kidney stones occur, you may need to reduce your consumption of animal protein, sodium, refined carbohydrates, or foods high in calcium and oxalate.

The most common side effects of Zyloprim include:

• High liver enzyme levels.
• Nausea.
• Skin rash.
• Headaches.
• Muscle pain or joint pain.
• Nerve pain.
• Changes or loss in taste.
• Drowsiness.
• Tiredness.
• Stomach upset.

Some individuals may experience serious side effects while using Zyloprim. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

• Rashes, hives, painful blisters, skin peeling and reddening, sore throat, fever, and enlarged lymph nodes are all signs of a severe skin reaction.
• Severe allergic reaction: breathing difficulties, facial swelling, and anaphylaxis (such as closure of the throat).
• Liver problems include extreme nausea, vomiting, weight loss, stomach discomfort on the right side, lack of appetite, exhaustion, and yellowing of the skin or eyes (jaundice).
• Fever, chills, weakness, unusual bleeding or bruises, and blood in the urine or stool are all signs of low blood cell counts.

These are not all of the possible side effects of allopurinol. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Zyloprim, it is crucial to discuss any existing health conditions with your healthcare provider. Some warnings associated with Zyloprim include:

• This medication may cause toxic epidermal necrolysis, Stevens-Johnson syndrome, and drug reaction with eosinophilia and systemic symptoms (DRESS), among other serious skin problems.
• Serious kidney problems or kidney disease could result from this medication.
• If you or your kid have any of the following symptoms: yellow eyes or skin, pale feces, black urine, nausea, loss of appetite, or unusual weakness or fatigue, consult your doctor immediately. These can indicate a severe liver problem.
• After taking allopurinol (Zyloprim), some persons may experience extreme vertigo or drowsiness. Your capacity to think, respond, and concentrate might be impacted by fatigue and dizziness.

• If you have a hypersensitivity to the drug or have had a severe skin reaction to the medication, do not use it.

For the medication to take effect, you must take oral allopurinol tablets for two to three days. Usually, your doctor would start you on a low dosage and raise it gradually over time. As a result, allopurinol typically takes one to three weeks to bring your blood uric acid levels down to normal.

When Zyloprim is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

• Thiazide diuretics, including hydrochlorothiazide and chlorthalidone.
• Azathioprine.
• Mercaptopurine.
• Amoxicillin.
• Ampicillin.
• Warfarin.
• Chlorpropamide.
• Colchicine.
• Cyclosporine.
• Theophylline.

Zyloprim can typically be taken once a day. Additionally, it can be divided into smaller doses throughout the day, particularly if the dosage exceeds 300 mg and if your situation explicitly calls for it.

The severity of your condition and your uric acid levels will determine how much you need to take. If you have kidney issues, it may also be different.

Gout: 100 mg taken orally daily is the usual starting dosage. After that, the dosage is usually increased to between 200 and 600 mg daily.

Elevated uric acid due to chemotherapy:

Adults: The usual dosage is 300–800 mg taken orally each day. A day or two before receiving chemotherapy, you will begin taking Zyloprim, and you will continue taking it for two or three days following your treatment.

Children: Take this medication orally every eight to twelve hours. Your child will begin taking Zyloprim a day or two before receiving chemotherapy and continue taking it for two or three days following the chemotherapy session.

The usual oral dosage for recurrent calcium oxalate kidney stones is 200–300 mg daily.

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take double doses.

Store Zyloprim at room temperature and keep it out of reach of children.

Casper Pharma LLC is the pharmaceutical company that manufactures Zyloprim.

Yes, there are several lower-cost versions of Zyloprim available.

You run a significant chance of experiencing severe side effects or gout flares if you abruptly stop taking allopurinol. Allopurinol should only be stopped when directed by a physician. To prevent severe side effects, a doctor will assist you in gradually lowering your dosage.

It is not known if Zyloprim is safe to take while pregnant. Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.

Zyloprim can get into breast milk, but it is not clear how it would affect your baby. Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.