Zyloprim

Zyloprim Drug Information

• Zyloprim Overview

  Allopurinol is used to treat gout and certain types of kidney stones. It is also used to prevent increased uric acid levels in patients receiving cancer chemotherapy. These patients can have increased uric acid levels due to release of uric acid from the dying cancer cells. Allopurinol works by reducing the amount of uric acid made by the body. Increased uric acid levels can cause gout and kidney problems.

• How to Use Zyloprim

  Take Zyloprim by mouth, usually once daily or as directed by your doctor. Take Zyloprim after a meal to reduce stomach upset. If your dose is more than 300 milligrams a day, you will need to take several smaller doses during the day to get this amount (ask your doctor for directions). It is best to drink a full glass of water with each dose and at least 8 more glasses (8 ounces each) of fluid a day. If your doctor has directed you to drink less fluid for other medical reasons, consult your doctor for further instructions. Your doctor may also instruct you on how to decrease acid in your urine (e.g., avoiding large amounts of ascorbic acid/vitamin C). Dosage of Zyloprim is based on your medical condition and response to treatment. Use Zyloprim regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day. For the treatment of gout, it may take up to several weeks for this medicine to have an effect. You may have more gout attacks for several months after starting this medicine while the body removes extra uric acid. Allopurinol is not a pain reliever. To relieve pain from gout, continue to take your prescribed medicines for gout attacks (e.g., colchicine, ibuprofen, indomethacin) as directed by your doctor. Tell your doctor if your condition persists or worsens.

• Zyloprim Precautions

  Before taking allopurinol, tell your doctor or pharmacist if you are allergic to it; or if you have had a severe reaction to it; or if you have any other allergies. Zyloprim may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using Zyloprim, tell your doctor or pharmacist your medical history,liver disease, kidney disease, diabetes, high blood pressure (hypertension), unusual diets (e.g., fasting). Zyloprim may make you drowsy. Alcohol or marijuana (cannabis) can make you more drowsy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Alcohol may also decrease the effectiveness of Zyloprim. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis). Kidney function declines as you grow older. Zyloprim is removed by the kidneys. Therefore, older adults may be at greater risk for side effects while using Zyloprim. During pregnancy, Zyloprim should be used only when clearly needed. Discuss the risks and benefits with your doctor. Allopurinol passes into breast milk. Consult your doctor before breast-feeding.

• Zyloprim Misdose

  If you miss a dose of Zyloprim, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

• Zyloprim Interactions

  Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (such as prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval."blood thinners" (e.g., warfarin), capecitabine, didanosine.

• Zyloprim Side Effects

  What are Zyloprim side effects?

  Side effects are physical, mental or emotional symptoms which occur in addition to or outside of the desired effect of a therapeutic treatment such as an over-the-counter or prescribed drug or medication. Side effects from Zyloprim may occur at the beginning or at the end of treatment and may also depend on the length of time an individual remains on the treatment. Side effects, also known as adverse effects, are generally more likely to occur when starting treatment. Individuals may also experience side effects from Zyloprim as a result of an interaction with other medications.

  Side Effects of Zyloprim

  The side effects of Zyloprim may vary in number and intensity for many different reasons. Factors such as age, weight, gender and ethnicity may influence the side effects of Zyloprim. Also, an individual’s state of general physical health and seriousness of the disease or illness as well as an increase or decrease in dosage may lead to side effects. Further, side effects from Zyloprim may also occur as a result of an interaction with certain herbal supplements, foods or drinks.

  Prescription drug side effects can be serious and may cause patients to stop the treatment. However, when side effects from the use of a prescription drug, such as Zyloprim, do occur a patient should consult their physician. A physician may prescribe an additional treatment in order to control the symptoms or an adjustment in the dosage may be made. In addition, changes to diet, exercise or other lifestyle activities may help to lessen the side effects of Zyloprim.

  By understanding side effects and the factors which may influence the occurrence of side effects patients are empowered to take an active role in their care. Patients who have specific questions about the side effects of Zyloprim, or any other medication, should contact their physician. General information about Zyloprim and the side effects associated with Zyloprim are described in the following:

  Common Zyloprim Side Effects

  Severe

  • allergic dermatitis
  • pruritus of skin
  • urticaria
  • skin rash

  Less Severe

  Less Frequent Zyloprim Side Effects

  Severe

  • abnormal hepatic function tests

  Less Severe

  Rare or Very Rare Zyloprim Side Effects

  Severe

  • bone marrow depression
  • aplastic anemia
  • anemia
  • thrombocytopenic disorder
  • agranulocytosis
  • peripheral neuropathy
  • vasculitis
  • hepatic necrosis
  • drug-induced hepatitis
  • obstructive hyperbilirubinemia
  • renal failure
  • kidney stone
  • erythema multiforme
  • toxic epidermal necrolysis
  • Stevens-Johnson syndrome
  • exfoliative dermatitis
  • onycholysis
  • jaundice
  • epistaxis
  • hypersensitivity drug reaction
  • purpura
  • DRESS syndrome
  • nephritis
  • cataracts
  • bronchospastic pulmonary disease
  • optic neuritis
  • lymphadenopathy
  • pancytopenia
  • hemolytic anemia
  • lymphocytosis
  • acute pancreatitis
  • gastrointestinal hemorrhage
  • hypercalcemia
  • pericarditis
  • bradycardia

  Less Severe

  • alopecia
  • drowsy
  • headache disorder
  • nausea
  • vomiting
  • diarrhea
  • abdominal pain with cramps
  • dysgeusia
  • ecchymosis
  • fever
  • gastritis
  • dyspepsia
  • eosinophilia
  • leukocytosis
  • leukopenia
  • myopathy
  • arthralgias
  • paresthesia
  • lichen planus
  • erectile dysfunction
  • hematuria
  • proteinuria
  • iritis
  • conjunctivitis
  • amblyopia
  • furunculosis
  • facial edema
  • edema
  • hyperhidrosis
  • asthma
  • pharyngitis
  • rhinitis
  • insomnia
  • acute confusion
  • dizziness
  • vertigo
  • libido changes
  • depression
  • memory impairment
  • tinnitus
  • general weakness
  • myalgias
  • anorexia
  • stomatitis
  • sialoadenitis
  • male infertility
  • gynecomastia
  • thrombophlebitis
  • vasodilation of blood vessels

• Zyloprim Storage

  Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard Zyloprim when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.