Zyvox

The active ingredient in Zyvox is linezolid, which is an oxazolidinone antibiotic. The mechanism of action involves inhibiting bacteria's ability to produce specific proteins. This inhibits bacterial growth and survival.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide, before using Zyvox. However, the following is a synopsis of the general guidelines for the use of Zyvox:

• Zyvox tablets or oral suspension may be taken with or without food.
• Zyvox is administered as an infusion into a vein by a healthcare professional.
• Do not use Zyvox unless you fully understand the directions for proper use. If you have any questions, ask your doctor or pharmacist.
• Turn the bottle upside down three or five times to gently mix the oral suspension. Don't shake. Use the included dosing syringe or a pharmaceutical dose-measuring instrument (not a kitchen spoon).
• Avoid large quantities of foods or beverages high in tyramine, like aged cheeses, red wine, and soy sauce.

The most common side effects of linezolid seen in clinical trials include:

• Nausea and diarrhea.
• Headaches.
• Tongue discoloration.
• Anemia (low red blood cell count).
• Low platelets.
• Stomach pain.
• Dizziness.
• Rash or itching.

Some individuals may experience serious side effects while using Zyvox. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

• Fever, pale skin, high heart rate, lightheadedness, and a general feeling of being poorly are symptoms of low blood cell counts.
• Symptoms of serotonin syndrome, including rapid heart rate, dizziness, perspiration, flushing, tremor (shakiness), muscle stiffness, muscle twitching or spasms, uncoordinated movement, and hallucinations. Your risk is increased when taking concomitant serotonergic medications, including antidepressants such as selective serotonin reuptake inhibitors (SSRIs) and opioids.
• C. difficile-related infectious diarrhea, characterised by a fast heart rate, fever, nausea, foul-smelling diarrhea, and frequent bowel movements.
• Lactic acidosis symptoms include fast breathing and frequent nausea and vomiting.
• Low sodium levels cause weakness, forgetfulness, memory issues, and difficulties concentrating.
• Severe allergic reactions include hives, rash, blisters, fever, swelling of the lips or tongue, and difficulty breathing.
• Peripheral neuropathy and optic neuropathy, sometimes leading to loss of vision.

These are not all of the possible adverse reactions of Zyvox. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Zyvox, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including whether you have:

• High blood pressure (hypertension).
• Myelosuppression (including anemia, leukopenia, pancytopenia, and thrombocytopenia), more so in people with renal impairments.
• Thyroid disorder.
• Bone marrow suppression or a weak immune system.
• Kidney disease or liver disease.
• Pheochromocytoma (adrenal gland tumor).
• Seizures.
• Diabetes.

• Currently taking or have taken a monoamine oxidase inhibitor (MAOI) in the past 14 days.
• Allergic reaction to the medication.

Linezolid takes about 2-3 hours to work. For adults, the medication is administered every 12 hours for 10 to 14 days.

When Zyvox is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

• Pseudoephedrine.
• Buspirone.
• Dextromethorphan.
• Dobutamine.
• Dopamine.
• Opioids.
• Phenylalanine.
• Phenylketonuria.
• Phenelzine.

Typical Zyvox dose for patients aged 12 and up ranges from 400 mg to 600 mg taken orally every 12 hours, depending on the type of infection and severity.

For children under 12 years of age, the average dose is 10 mg/kg of body weight every 8 or 12 hours. The prescribed dose will be determined by your child's age, weight, the type of infection, and the severity of the condition.

Most treatments last 10 to 14 days. Treatment for more serious infections can take up to four weeks.

Zyvox can also be administered intravenously (IV) by a healthcare professional to treat more serious infections.

Store at room temperature and keep out of reach of children.

Pfizer is the pharmaceutical company that manufactures Zyvox.

There are lower-cost generic versions available.

It is important to finish your course of therapy. Speak to your healthcare provider before suddenly stopping Zyrox.

It is not clear whether Zyvox is safe to take while pregnant. Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.

Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you. Lactating women should keep an eye out for diarrhea and vomiting in their breastfed infants if taking Zyvox.