Bumex

The active ingredient in Bumex is bumetanide, which is a loop diuretic. It reduces swelling by helping the kidneys eliminate excess water and electrolytes (such as potassium and sodium) through your urine.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide, before using Bumex. However, the following is a synopsis of the general guidelines for the use of Bumex:

• Bumex will cause you to urinate more often. To avoid having to get up in the middle of the night to urinate, try taking Bumex earlier in the day.
• Dizziness and lightheadedness are possible side effects of bumetanide (Bumex), particularly in the initial days of treatment. Get up slowly from a sitting or lying position to reduce the likelihood of experiencing vertigo. Until you know how this drug affects you, stay away from driving and other activities that require a lot of focus. Inform your healthcare provider immediately if you think you might faint or pass out.
• When using bumetanide (Bumex), your doctor may ask you to weigh yourself. This can help them determine whether you need to change your dosage and how successfully bumetanide (Bumex) is removing fluids from your body.

Some common side effects of Bumex include:

• Changes in electrolyte levels.
• Muscle cramps.
• Dizziness.
• Nausea and vomiting.
• Headaches.
• Low blood pressure (hypotension).
• Hypocalcemia (low calcium in the blood).

Some individuals may experience serious side effects while using Bumex. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

• Severe dehydration manifests as dark urine, dry mouth, lightheadedness, thirst, and decreased urination.
• Low blood potassium levels (hypokalemia) can cause tingling or numbness, fatigue, heart palpitations, constipation, nausea, vomiting, muscle soreness, and disorientation.
• Skin pain, fever, body aches, red rash, peeling skin, blisters, and sores are symptoms of Stevens-Johnson Syndrome or toxic epidermal necrolysis.
• Allergic reaction to the medication, such as hives, skin rash, chest pain, or swelling of the throat or face.
• Hearing loss (ototoxicity).
• Low platelet counts.

These are not all of the possible side effects of Bumex. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Bumex, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including whether you have:

• Severe kidney disease or are unable to urinate.
• Liver disease or cirrhosis.
• Dehydration.
• An electrolyte imbalance, such as low levels of potassium or magnesium in the blood.
• Irregular heartbeat (arrhythmia).
• Congestive heart failure.
• Gout.
• An allergy to sulfonamides.
• A low-salt diet.

• Not urinating.
• Liver (hepatic) coma.
• Very low amounts of electrolytes.

Although bumetanide begins to act within an hour, it can take a few weeks for it to fully take action.

When Bumex is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

• Lithium.
• Digoxin.
• Probenecid.
• Indomethacin.
• Certain blood pressure medications.
• Other diuretics like furosemide.

Bumex is typically given orally once daily at a dose of 0.5–2 mg. To reduce your swelling, your doctor will change your dosage as necessary. Your doctor may prescribe Bumex every other day, depending on your situation. The maximum daily dose is 10 mg per day.

Store your Bumex tablets at room temperature and keep them out of reach of children.

Validus Pharmaceuticals, LLC. is the pharmaceutical company that manufactures Bumex.

There are several lower-cost generic versions available of Bumex.

If you wish to stop taking Bumex, consult your physician. Your body may accumulate fluid if you stop. Your doctor might be able to recommend an alternative medication if side effects are bothering you.

Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.

Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.