Buscopan Plus

(Hyoscine Butylbromide/Acetaminophen)

The active ingredients in Buscopan Plus are hyoscine-n-butylbromide and paracetamol. Hyoscine-n-butylbromide belongs to the drug class known as antispasmodics. It works by relaxing the smooth muscles found in the gastrointestinal tract. Paracetamol works as an analgesic. Together, this helps relax cramped muscles while also relieving pain.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Buscopan Plus. However, the following is a synopsis of the general guidelines for the use of Buscopan Plus:

• The recommended dose is to take one tablet three times daily.
• Ensure that the total daily dose of 6 tablets is not exceeded.
• If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and only take the next dose.

The most common side effects of Buscopan Plus include:

• Constipation
• Dry mouth
• Urinary retention
• Blurred vision
• Fast heart rate
• Dizziness
• Diarrhea

Some individuals may experience serious side effects while using Buscopan Plus. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

• Severe allergic reaction: difficulty breathing, anaphylactic shock, skin reactions, including rashes or hives
• Life-threatening skin conditions, including Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN)
• Severe, unexplained abdominal pain that does not go away or worsens; may occur with fever, nausea, or vomiting
• Liver damage with high doses of paracetamol
• Vision changes and worsening glaucoma

These are not all of the possible side effects of Buscopan Plus. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Buscopan Plus, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including:

• Myasthenia gravis
• Known allergy to Buscopan
• Bowel obstruction (ileus)
• Prostate problems, including prostatic hypertrophy
• Megacolon
• Glaucoma

• Hypersensitivity to this medication or any of its inactive ingredients, including carnauba wax, povidone, calcium hydrogen phosphate, stearic acid, tartaric acid, titanium dioxide, acacia
• Myasthenia gravis
• Megacolon
• Glaucoma
• Intestinal blockage
• Serious liver or kidney problems

This medication will typically begin working within 15 minutes.

When Buscopan Plus is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

• Tricyclic antidepressants
• Other painkillers
• Antipsychotics
• Metoclopramide
• Antihistamines
• Amantadine
• Atropine
• Medications that control heart rate, including quinidine

The dosage forms available include the oral Buscopan tablet, which contains 10 mg of hyoscine butylbromide and 500 mg of paracetamol.

This medication should be stored at room temperature and away from the reach of children.

The pharmaceutical company that manufactures Buscopan is Sanofi.

There are lower-cost alternatives to the brand-name Buscopan Plus.

Before stopping this medication, consult your healthcare provider.

This medication is generally not recommended to be taken during pregnancy. Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.

It is not known if Buscopan is found in breast milk and is generally not recommended for use during lactation. Notify your doctor if you are already breastfeeding or if you have any plans to breastfeed.