Chronulac is used by mouth or rectally to treat or prevent complications of liver disease (hepatic encephalopathy). It does not cure the problem, but may help to improve mental status. Lactulose is a colonic acidifier that works by decreasing the amount of ammonia in the blood. It is a man-made sugar solution.
How to Use Chronulac
If you are taking Chronulac by mouth for liver disease, take it usually 3-4 times a day or as directed by your doctor. To improve the taste, you may mix it into fruit juice, water, milk, or a soft dessert. The goal is to have 2-3 soft stools each day. Dosage of Chronulac is based on your medical condition and response to therapy (i.e., the number of soft stools each day). If you are taking Chronulac by mouth for constipation, take it usually once daily or as directed by your doctor. Chronulac can also be given rectally as an enema for liver disease. Mix the recommended amount of lactulose with 700 milliliters (24 ounces) of water or normal saline. Give the solution into the rectum and keep the liquid inside for 30-60 minutes as directed by your doctor. If you keep the enema inside for less than 30 minutes, repeat the dose unless directed otherwise. Use Chronulac regularly in order to get the most benefit from it. Remember to use Chronulac at the same time each day. When Chronulac is given rectally for liver disease, an improvement in your mental status may occur in as little as 2 hours, but if you are taking Chronulac by mouth, it may take up to 24 to 48 hours. If you are using Chronulac for constipation, it may take up to 48 hours to have a bowel movement. Tell your doctor if your condition lasts or gets worse.
Before using lactulose, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Chronulac may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using Chronulac, tell your doctor or pharmacist your medical history,a low galactose diet (such as a diet that includes few or no milk products), certain other bowel problem (bowel obstruction), diabetes. Do not take any laxative medications while using Chronulac. Frequent use or overuse of laxatives can cause dehydration. This is especially likely to occur in children or older adults.muscle weakness, muscle cramps, dizziness. Before having surgery or other procedures (such as electrocautery), tell your doctor or surgeon that you are using Chronulac. Chronulac contains different sugars. If you have diabetes, Chronulac may affect your blood sugar. Check your blood sugar regularly as directed and share the results with your doctor. Your doctor may need to adjust your diabetes medication, exercise program, or diet. During pregnancy, Chronulac should be used only when clearly needed. Discuss the risks and benefits with your doctor. It is not known whether Chronulac passes into breast milk. Consult your doctor before breast-feeding.
If you miss a dose of Chronulac, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.antacids containing aluminum and/or magnesium, other laxatives (such as cleansing enemas with soap suds).
Chronulac Side Effects
Gas, bloating, burping, stomach rumbling/pain, nausea, and cramps may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Remember that Chronulac has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using Chronulac do not have serious side effects. Tell your doctor right away if you have any serious side effects,diarrhea, vomiting, muscle cramps/weakness, irregular heartbeat, mental/mood changes, seizures. A very serious allergic reaction to Chronulac is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction,rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Store between 36-86 degrees F (2-30 degrees C) away from light and moisture. Do not freeze because this will make the medication too thick to pour. If it becomes frozen, warm it to room temperature until it is pourable again. A normal darkening of color may occur. If too much darkening occurs and you cannot swallow it, discard the medication and get a refill. Do not store in the bathroom. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard Chronulac when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
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