Drixoral

The active ingredient in Drixoral is oxymetazoline hydrochloride. Oxymetazoline is a nasal decongestant that works by narrowing the blood vessels in the nasal passages, reducing swelling and sinus congestion. This helps ease breathing by opening up the nasal passages and relieving your stuffy nose.

The active ingredient is also used in combination products to treat other allergy or cold symptoms like a runny nose, watery eyes, sneezing, and fever.

Follow all directions given to you by your healthcare provider and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Drixoral. However, the following is a general guideline:

• The usual dose of Drixoral nasal spray is 2 to 3 sprays in each nostril every 12 hours as needed, but this may vary based on your healthcare provider's recommendations.
• To use Drixoral for the first time, prime the pump by spraying it 4 times. Then, clear your nose and hold the spray bottle with your thumb under the base and nozzle between two fingers. Insert the nozzle into the nostril and spray and breathe in gently at the same time. Repeat with the other nostril. Afterward, clean the nozzle and put the cap back on.
• Do not use Drixoral for more than 3 consecutive days. Frequent or prolonged use may cause rebound nasal congestion.
• Drixoral may interact with certain medications. Please see the section about drug interactions.

Some mild or common side effects of Drixoral seen in clinical trials as compared to a placebo include:

• Runny nose.
• Sneezing.
• Trouble sleeping.
• Dizziness.
• Nausea.
• Headache.

In some cases, individuals may experience more serious side effects. These could require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

• Fast or irregular heartbeat.
• Allergic reaction. Symptoms include swelling of the face, lips, or throat, and shortness of breath.
• Severe dizziness or confusion.

These are not all of the possible side effects of Drixoral. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Drixoral, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including if you have:

• High blood pressure.
• Glaucoma.
• Difficulty urinating due to an enlarged prostate.
• Thyroid disorders, such as hyperthyroidism.
• Tendency to have nosebleeds.
• Phaeochromocytoma.

• Do not use in children under 12 years old.
• Allergic to any ingredient in Drixoral.
• If you have had your trans-nasal surgery.
• Are currently taking monoamine oxidase (MAO) inhibitors (e.g., phenelzine, tranylcypromine).
• If you have narrow-angle glaucoma.
• If you have chronic nasal inflammation with dry nasal passages.

Drixoral generally begins to relieve nasal congestion within 15 minutes of using it.

When Drixoral is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure to inform your healthcare provider about anything you are currently taking, including:

• Other decongestants or nasal sprays.
• Antidepressants (particularly MAO inhibitors like selegiline and tranylcypromine).
• High blood pressure medications or medications that affect the heart.
• Thyroid medications.
• Antihistamines that cause drowsiness.
• Certain cold or allergy medications.

Drixoral is available in a 0.05% solution of oxymetazoline hydrochloride. For more product information, please see the manufacturer’s website.

Store Drixoral at room temperature, away from moisture and heat. Keep it in its original packaging, and ensure it is out of the reach of children. Do not use the medication after the expiration date on the label.

Drixoral is manufactured by Bayer Inc.

Yes, generic versions of Drixoral are available. The generic name is oxymetazoline nasal spray.

If you no longer need Drixoral or if your symptoms improve, you can stop using it. However, do not suddenly stop using Drixoral if you have been using it regularly for a long period. If you have concerns about discontinuing the medication, consult with your healthcare provider for guidance.

Based on limited human data, it is not known if oxymetazoline crosses the human placenta. Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.

Drixoral (oxymetazoline) is likely compatible in breastfeeding. Oxymetazoline may be excreted in the breast milk, but there is limited absorption into the body from the nasal spray. Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.