Edronax

The active ingredient in Edronax is reboxetine. It is a noradrenaline reuptake inhibitor or norepinephrine reuptake inhibitor (SNRI). It only has a weak effect on serotonin receptors and reuptake and will not affect the uptake of dopamine. This action allows for the noradrenaline molecules to stay in the synapse for longer, which aids in the treatment of major depression.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-approved product Labeling, Instructions for Use, and Medication Guide, before using Edronax. However, the following is a synopsis of the general guidelines for the use of Edronax:

• The oral tablet can be taken with or without food. It is typically twice daily.
• If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and only take the next dose. Do not take double or extra doses.

The most common side effects of Edronax seen in clinical trials as compared to placebo include:

• Dry mouth
• Constipation
• Stimulation of the central nervous system (CNS)
• Dizziness
• Nausea and vomiting
• Stomach pain
• Erectile dysfunction
• Increased heart rate (tachycardia) and palpitations
• Loss of appetite

Some individuals may experience serious adverse reactions while using Edronax. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

• Skin is more easily bruised
• An allergic reaction
• Increased incidence of seizures
• Mixed/manic episode in patients at risk of bipolar disorder
• Worsening depression and suicidal ideation
• Serotonin syndrome, which can be life-threatening
• Involuntary muscle movements

These are not all of the possible side effects of Edronax. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Edronax, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including whether you have:

• Narrow-angle glaucoma
• Liver disease
• Kidney disease
• Heart problems, including high blood pressure (hypertension)
• Seizure disorder
• Bipolar disorder
• Prostate problems or trouble urinating
• A condition being treated with other medications that increase serotonin levels

Known allergy to Edronax or any of the inactive ingredients in the product, such as crospovidone, cellulose, calcium hydrogen phosphate, and magnesium stearate

Reboxetine, the active ingredient in Edronax, has a half-life of about 13 hours. While the full effects of reboxetine will take around 4-6 weeks, some symptom improvement may be seen after 2 weeks of treatment.

When Edronax is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

• Lithium
• St. John’s wort
• Monoamine oxidase inhibitors (MAOIs)
• Carbamazepine
• CYP3A4 inhibitors, including fluvoxamine
• Selective serotonin reuptake inhibitors (SSRIs) like fluoxetine
• Tricyclic antidepressants

Edronax is available in 2 mg and 4 mg tablets. The recommended maintenance dose is 4 mg by mouth twice daily (8 mg/day). After 3 weeks, the dose may be increased up to a maximum of 10 mg/day.

This medication should be stored at room temperature and away from the reach of children and adolescents.

The pharmaceutical company that manufactures Edronax is Pfizer Australia Pty Ltd.

There are lower-cost alternatives for the brand-name Edronax.

Edronax is a medication that requires a gradual taper-off with the guidance of your physician.

There is no information from clinical studies about the safety of taking Edronax during pregnancy. Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.

Edronax may pass into breast milk and affect your nursing baby. Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.