Elavil

The active ingredient in Elavil is amitriptyline hydrochloride. Elavil operates on the central nervous system (CNS) to increase levels of natural chemical messengers in the brain, namely norepinephrine and serotonin. These neurotransmitters communicate between brain cells and aid in regulating mood.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Elavil. However, the following is a synopsis of the general guidelines for the use of Elavil:

• Take Elavil by mouth as directed by your doctor.
• You can take Elavil with or without food.
• If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and only take the next dose. Do not take double or extra doses.

The most common side effects of Elavil include:

• Constipation.
• Trouble urinating.
• Weight gain.
• Dry mouth.
• Drowsiness.
• Blurred vision.
• Nausea and vomiting.
• Dizziness.

Some individuals may experience serious side effects while using Elavil. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

• Severe allergic reactions - skin rash, itching, hives, and swelling.
• Heart rhythm changes - fast or irregular heartbeat, feeling lightheaded, chest pain, trouble breathing.
• Serotonin syndrome - irritability, confusion, twitching muscles, sweating, high fever, seizure, diarrhea.
• Sudden eye pain or vision loss.
• Worsening mood or suicidal thoughts.

These are not all of the possible side effects of Elavil. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Elavil, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including if you have:

• Glaucoma.
• History of heart disease or heart attack.
• Diabetes or high blood sugar levels.
• High blood pressure (hypertension).
• Overactive thyroid.
• Bipolar disorder, mania, or schizophrenia.
• Liver problems.
• Urinary retention (problems with urination).
• History of stroke or seizure.

Boxed Warning

• In some studies, antidepressants increased the risk of suicidal thinking and behavior in children, adolescents, and young adults (<24 years) taking antidepressants. Elavil is not approved for use in pediatric patients <12 years of age.

• Currently taking or have taken an MAOI within the last 14 days
• Had a recent heart attack

Individuals can start to feel better after 1 to 2 weeks, but it can take 4 to 6 weeks for you to see the full effects of Elavil.

When Elavil is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

• St. John's Wort.
• Monoamine oxidase inhibitor (MAOI) within the past 2 weeks (phenelzine, tranylcypromine).
• Selective serotonin reuptake inhibitor (SSRI) or a serotonin-norepinephrine reuptake inhibitor (SNRI).
• Antipsychotic medicines for mental health conditions.
• Thyroid medicines (levothyroxine).
• Medicines that cause dizziness.
• Anticholinergic medicines, including antihistamines.
• Medicines commonly used for overactive bladder, Parkinson’s disease, or stomach problems (cimetidine, cisapride).

Elavil comes in multiple strengths in oral tablets including:

• 10 mg, 25 mg, 50 mg, 75 mg, 100 mg, and 150 mg.

Store this medication at room temperature away from moisture and heat. Keep out of reach of children.

AA Pharma is the pharmaceutical company that manufactures the brand name Elavil.

There are lower-cost generics of Elavil available.

Serious withdrawal symptoms can occur if Elavil use is stopped suddenly. Consult your doctor on how to safely stop using Elavil.

It is not known if or how Elavil could affect pregnancy or harm an unborn baby. Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.

Elavil can pass into breast milk. Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.