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(Lactulose)

What is Lactulose?

What is Lactulose?

Enulose is a brand-name laxative used to treat chronic constipation and hepatic encephalopathy, a condition linked to liver disease. It contains lactulose, a synthetic sugar that helps soften stools and improve bowel movements. It is also used to lower ammonia levels in the blood in patients with liver problems.

Enulose is available as an oral solution and is commonly prescribed when other treatments for constipation are not effective. It may also be used as part of a broader treatment plan for portal-systemic encephalopathy or an enema. This medication should be used under the guidance of a healthcare provider.

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Purchase Lactulose from Universal Drugstore today and save!

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  • All Strength's
  • 10g/15mL

brand Versions

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Please see generic options below.

Lactulose (generic Lactulose)

What are generics?

Lactulose 
10g/15mL

Prescription Required
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Please note: 667mg/mL is equivalent to 10gm/15mL. Also please note that due to shipping restrictions we can only ship a maximum of 1 bottle of Lactulose at at time.
Prescription Required
Product of Canada

Product of Canada

Marketed as Jamp-Lactulose 667mg/mL in Canada.

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Important information about Lactulose

The active ingredient in Enulose is lactulose.

Lactulose is a disaccharide that is not absorbed into the bloodstream. Instead, it is broken down by bacteria in the colon into acids that draw water into the bowel. This softens the stool and increases the number of bowel movements. In patients with liver disease, lactulose helps reduce ammonia levels by changing the environment in the colon, which helps remove toxins from the body. This mechanism of action supports both relief of constipation and management of hepatic encephalopathy.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Enulose. However, the following is a synopsis of the general guidelines for the use of Enulose:

  • Take Enulose exactly as prescribed by your healthcare provider.
  • It is usually taken as an oral solution.
  • Measure each dose carefully using a proper measuring device.
  • It may be taken with water, milk, or fruit juice to improve taste.
  • The dose may be adjusted based on the number of bowel movements per day.
  • For hepatic encephalopathy, the goal is to have two to three soft bowel movements daily.
  • Do not take more than prescribed.
  • If you miss a dose, take it as soon as you remember unless it is close to your next dose. Do not take two doses at once to make up for a missed dose.

Some mild or common side effects of Enulose seen in clinical trials as compared to placebo include:

  • Bloating.
  • Flatulence.
  • Abdominal cramps.
  • Stomach cramps.

Some individuals may experience serious side effects while using Enulose. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

  • Severe diarrhea.
  • Signs of dehydration, such as dizziness or weakness.
  • Electrolyte imbalance, which may cause confusion or irregular heartbeat.
  • Severe abdominal pain.
  • Signs of an allergic reaction, such as hives, swelling, or trouble breathing.

These are not all of the possible side effects of Enulose. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Enulose, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including if you have:

  • Diabetes or concerns about blood sugar levels.
  • A history of electrolyte imbalance.
  • Gastrointestinal conditions or bowel obstruction.
  • Liver disease or hepatic encephalopathy.

Additional precautions:

  • Prolonged use may lead to electrolyte imbalances.
  • Monitor bowel movements and adjust dose as directed.
  • Use caution in pediatric patients and elderly individuals.
  • Inform your healthcare provider before undergoing procedures such as a colonoscopy or proctoscopy.
  • Avoid excessive use to prevent diarrhea and dehydration.

Enulose should not be used in the following situations:

  • Known hypersensitivity to lactulose or any component of the formulation.
  • Conditions requiring a low-galactose diet, due to the presence of galactose and lactose.

Enulose may take 24 to 48 hours to relieve constipation. For hepatic encephalopathy, it may begin to lower ammonia levels within a few days, but ongoing treatment is usually needed for full benefit.

When Enulose is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

  • Antacids, which may reduce the effectiveness of lactulose by altering intestinal acidity.
  • Antibiotics, which may reduce the breakdown of lactulose in the colon and decrease its effectiveness.

Enulose is available as an oral solution.

  • The dose for constipation is adjusted based on response and may vary by patient.
  • For hepatic encephalopathy, dosing is adjusted to achieve two to three soft bowel movements per day.
  • Your healthcare provider will determine the correct dosage based on your condition.

It should be stored at room temperature, away from the reach of children or pets.

Enulose is manufactured by several pharmaceutical companies, including generic manufacturers such as Teva Pharmaceuticals.

Yes, Enulose is available as a generic medication. The generic name is lactulose oral solution.

Enulose should not be stopped without consulting your healthcare provider, especially if used for hepatic encephalopathy.

  • Your healthcare provider may adjust your dose gradually.
  • Stopping suddenly may lead to worsening symptoms.
  • Always follow medical advice when discontinuing treatment.

Enulose (lactulose) can generally be used during pregnancy, as it is not absorbed into the body and is not expected to harm the baby. It is commonly recommended by healthcare professionals as a safe osmotic laxative for treating constipation when lifestyle changes (such as increased fiber and fluids) have not worked.

Enulose (lactulose) is generally considered safe to use while breastfeeding. It is often deemed a laxative of choice during lactation because it is poorly absorbed by the body, making it highly unlikely to pass into breast milk in significant amounts.

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Important information about buying Lactulose from UniversalDrugstore™

Once you complete your order, we process, verify, and dispatch your medication. You’ll receive email updates at each stage, including tracking details once your order ships. If any additional documentation is needed (such as a valid prescription), we’ll contact you promptly. Once approved, your order is charged and delivered directly to your doorstep.

Orders are typically processed within 1–3 business days once all required documents are received and approved. Standard delivery times range from 10–18 business days, depending on your location.

Yes! Once your medication ships, you will receive an email with tracking information so you can monitor your shipment every step of the way.

Our Customer Care team is available 24/7 to assist with any order-related concerns or questions. If you experience delays, missing items, or need support, contact us using the details provided in your confirmation email.

All orders are shipped in discreet, plain packaging to protect your privacy. Medications are securely packaged to prevent damage and ensure they arrive in top condition.

Yes. We use cold-chain shipping methods to safely transport temperature-sensitive medications, ensuring they maintain proper storage conditions throughout delivery.

Shipping costs vary depending on your location and shipping method. Free shipping promotions may be available—check the checkout page for the latest offers. Orders above $100 going to a US destination will receive free shipping.

Currently, we do not bill Medicare or Medicaid directly. However, we provide detailed receipts and documentation that you can submit to your insurance provider for potential reimbursement.

Universal Drugstore does not bill private health insurance directly, but we provide a detailed invoice that you can submit to your insurer for possible reimbursement. Many insurers will accept Universal Drugstore’s documents, but if you have any questions, check with your insurance company prior to purchasing.

We use advanced SSL encryption and secure payment processing to ensure that all transactions are 100% protected against fraud and unauthorized access.

Universal Drugstore offers many generic alternatives that provide the same active ingredients at a lower cost. Search for your medication and compare pricing for generic vs. brand-name options. Generic availability depends on the medication.

If your medication requires a prescription, you must upload it online, via email, or fax. Over-the-counter (OTC) medications do not require a prescription. All prescription medication purchases require a valid and approved prescription. The Universal Drugstore customer care team can contact your doctor directly to get your prescription, and ensure all information is up to date.

Yes! You can add multiple medications to your cart, including prescription, OTC, and pet medications, and complete your purchase in a single checkout process.

Yes! If your prescription includes refills, you can reorder quickly by logging into your account and selecting your medication for a hassle-free refill process. Always refill your medication proactively and ontime, to ensure you do not run out of important medication.

Yes! We offer:

  • Up to 80% savings on medications
  • Price match guarantee – we’ll match competitor pricing on qualifying medications
  • 10% off your first order for new customers

We offer 24/7 customer support via phone, email, and chat. Visit our Contact Us page for assistance with ordering, shipping, or medication questions.

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The information, including but not limited to, text, graphics, images and other material contained on this website are for informational purposes to increase health awareness only. No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. 



Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website.